Autism Spectrum Disorder: Diagnosis, Treatment, and Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 315

Special Issue Editor


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Guest Editor
School of Human and Health Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK
Interests: ADHD; neurodevelopmental disorders; autism; AI in mental health; service development
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Special Issue Information

Dear Colleagues,

We are organizing a Special Issue on adult Autism, specifically focusing on the clinical pathway from pre-diagnosis, and referral to diagnostic and support approaches.

Adult Autism, although long recognised, has gained increasing attention in recent years due to advancements in understanding and awareness. Areas of focus have included neuropsychology, biological markers, genetic markers, neuroanatomy, and neuroimaging, contributing to a deeper understanding of Autism across the lifespan.

Globally, there seems to be increased demand for assessments and support services for Autism, accompanied by developments in diagnostic and intervention methods. In addition to refining the conceptualisation of Autism as it applies to different populations, there is growing interest in how Autism manifests in specific medical groups, such as adults with co-occurring mental health conditions or physical health issues. The overlap between Autism and other neurodevelopmental and psychiatric disorders remains an area of ongoing research.

In this context, technology has emerged as a significant tool in Autism diagnostics, with innovations such as AI-driven assessments and wearable devices showing promise. The pace of technological advancement in this field is notable, offering potential improvements in the accuracy and accessibility of Autism diagnostics.

Regarding support approaches, various therapeutic models have been studied, ranging from pharmacological interventions to psychological and other supportive methods aimed at achieving a more comprehensive approach to care beyond traditional medication.

This Special Issue is designed to collect articles focusing on new populations where Autism may be under-recognised, new diagnostic approaches, and innovative support and intervention strategies. It welcomes contributions from diverse disciplines that can add to this important discussion.

Prof. Dr. Marios Adamou
Guest Editor

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Keywords

  • adult autism (including autism spectrum disorders)
  • neurodevelopmental disorders
  • clinical diagnostics
  • digital diagnostics
  • artificial intelligence
  • multimodal treatments

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Published Papers (1 paper)

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Research

9 pages, 703 KiB  
Article
Enhancing Adult Autism Diagnostic Pathways: The Role of Clinical Triage in Efficient Service Provision
by Marios Adamou, Sarah L. Jones, Tim Fullen, Bronwen Alty, Jennifer Ward and Joanne Nixon Mills
J. Clin. Med. 2025, 14(9), 2933; https://doi.org/10.3390/jcm14092933 - 24 Apr 2025
Viewed by 132
Abstract
Background: Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition affecting 1.1% of adults. The increasing incidence of ASD has led to pressurised diagnostic services. Objective: We aimed to determine the number needed to harm (NNH) of criteria-informed triage assessment in [...] Read more.
Background: Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition affecting 1.1% of adults. The increasing incidence of ASD has led to pressurised diagnostic services. Objective: We aimed to determine the number needed to harm (NNH) of criteria-informed triage assessment in an adult autism diagnostic service in the UK. Methods: The study was conducted at a specialist adult Autism Service in West Yorkshire, UK, from November 2021 to August 2022. All eligible referrals were accepted, with criteria requiring service users to be over 18 years old and without an intellectual disability. The evaluation consisted of 60 cases. Results: None of the evaluation cases resulted in a clinical diagnosis of ASD, yielding an infinite number needed to harm (NNH), demonstrating that every case benefited from the triage process without significant risk of harm. Conclusions: Triage enables services to gather comprehensive information about individual presentations and clinical needs, facilitating informed decision-making and better service utilisation. The evaluation demonstrates the safety and effectiveness of the triage process, with directions for further research discussed. Full article
(This article belongs to the Special Issue Autism Spectrum Disorder: Diagnosis, Treatment, and Management)
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