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Management of Ligaments and Tendons Injuries

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 903

Special Issue Editor


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Guest Editor
Hallym University Dongtan Sacred Heart Hospital, Hwaseong-si 18450, Republic of Korea
Interests: tendinopathy; ligaments; tendons

Special Issue Information

Dear Colleagues,

Ligaments and tendons are crucial connective tissues that ensure joint stability and coordinated movement. Injuries to these structures—such as anterior cruciate ligament (ACL) tears or rotator cuff tendinopathy—are increasingly prevalent among athletes, physically active individuals, and even the general population due to trauma or repetitive stress.

Managing ligament and tendon injuries remains a clinical challenge, necessitating precise diagnosis, individualized treatment planning, and optimized rehabilitation strategies. This Special Issue aims to present recent advancements and evidence-based approaches across the continuum of care—from innovative diagnostic modalities to novel surgical techniques, biologic therapies, and post-operative rehabilitation.

By uniting perspectives from orthopedic surgeons, sports medicine experts, rehabilitation specialists, and translational researchers, this Special Issue aspires to foster interdisciplinary dialogue and improve the clinical outcomes of patients suffering from these complex musculoskeletal injuries.

Dr. Vivek Kumar Morya
Guest Editor

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Keywords

  • tendinopathy
  • ligaments
  • tendons
  • anterior cruciate ligament (ACL)
  • rotator cuff

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Published Papers (1 paper)

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Research

15 pages, 1093 KB  
Article
Effectiveness of Ultrasound-Guided Peritendinous Injection Treatment with Low Molecular Weight Hyaluronic Acid in Patients with Supraspinatus Tendinopathy
by Francesco Agostini, Alessandro de Sire, Alessio Savina, Giovanni Iudicelli, Andrea Fisicaro, Giacomo Camponogara, Marco Narciso, Alessio Fricano, Marco Conti, Umile Giuseppe Longo, Valter Santilli, Antonio Ammendolia, Massimiliano Mangone and Marco Paoloni
J. Clin. Med. 2025, 14(17), 6291; https://doi.org/10.3390/jcm14176291 - 5 Sep 2025
Viewed by 737
Abstract
Background/Objectives: Tendinopathies represent a prevalent musculoskeletal condition characterized by load-dependent pain, stiffness, weakness, and impaired functionality. Current treatment includes therapeutic exercise, physical modalities and injective therapy. Hyaluronic acid (HA) is a fundamental component of the extracellular matrix and plays a crucial role [...] Read more.
Background/Objectives: Tendinopathies represent a prevalent musculoskeletal condition characterized by load-dependent pain, stiffness, weakness, and impaired functionality. Current treatment includes therapeutic exercise, physical modalities and injective therapy. Hyaluronic acid (HA) is a fundamental component of the extracellular matrix and plays a crucial role in tissue hydration, elasticity, and lubrication. This study aims to evaluate the effectiveness of ultrasound-guided injections of HA in improving pain symptoms and functionality in patients with supraspinatus tendinopathy. Methods: Patients with a confirmed diagnosis of supraspinatus tendinopathy, verified through ultrasound imaging, were included in the study. Patients underwent 3 ultrasound guidance injections (1/week) of Sodium Hyaluronate (Hyalotend, 20 mg/2 mL). Patients were evaluated at the baseline, 1 month (T1), 3 months (T2), 6 months (T3), and 1 year (T4) after the first injection through the VAS, the QuickDASH and the SF-12. Results: Twenty-four patients were enrolled. As regards the VAS there was a statistically significant reduction (p < 0.01) of averages of values over time. The scores collected through the QuickDASH questionnaire have a statistically significant variation over time (p < 0.001). The values collected through the SF-12 Mental Component Summary (MCS) questionnaire show a highly statistically significant variation over time (p < 0.005). The values collected through the SF-12 Physical Component Summary (PCS) questionnaire show a statistically highly significant change over time (p < 0.001). Conclusions: Our results suggest that HA (Hyalotend) injections could represent a viable therapeutic option for patients with supraspinatus tendinopathy in the short, medium, and long term. Further studies with larger patient samples and a control group are needed to better investigate the effects and the modalities of administration of HA in tendinopathies. Full article
(This article belongs to the Special Issue Management of Ligaments and Tendons Injuries)
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