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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Pain: Non-Pharmacological Treatments and Rehabilitation Strategies

edited by Matteo Ponzano

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2625 | Submission Open

Keywords: pain; neuropathies; musculoskeletal health; biopsychosocial management; physical therapy; cognitive behavioral therapies

(This special issue belongs to the Section Clinical Rehabilitation)

Diagnosis and Treatment of Rheumatic Diseases

edited by Răzvan Gabriel Drăgoi and

Codrina Ancuta

submission deadline 30 Jun 2025 | 3 articles | Viewed by 2619 | Submission Open

Keywords: rheumatic diseases; patient-reported outcomes; assessment; arthritis; impairment; connective tissue diseases; biological and targeted synthetic therapies; impairment

(This special issue belongs to the Section Immunology)

Clinical Advances in Urinary Surgery

edited by Nir Kleinmann and

Asaf Shvero

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2545 | Submission Open

Keywords: endourology; laparoscopic urology; urologic oncology; urolithiasis; robot-assisted surgery; endoscopic surgery

(This special issue belongs to the Section Nephrology & Urology)

Cerebral Palsy: Clinical Rehabilitation and Treatment

edited by Joav Merrick and

Dilipkumar R. Patel

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2490 | Submission Open

Keywords: cerebral palsy; physiotherapy; occupational therapy; orthopedic management; medical management; rehabilitation approaches

(This special issue belongs to the Section Clinical Neurology)

Perspectives on Congenital Heart Disease from Children to Adults

edited by

Raffaele Giordano

submission deadline 30 Jun 2025 | 4 articles | Viewed by 2266 | Submission Open

Keywords: congenital heart disease; pediatric cardiac surgery; pediatric cardiology; children; adult congenital heart disease

(This special issue belongs to the Section Cardiology)

Current Challenges in the Management of Vitreoretinal Conditions: 2nd Edition

edited by

Georgios Panos

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2252 | Submission Open

Keywords: retina; anti-VEGF; implants; macular degeneration; diabetic retinopathy; vein occlusions; retinal detachments; vit-reoretinal surgery; COVID-19 impact

(This special issue belongs to the Section Ophthalmology)

Pelvic Organ Prolapse: Current Challenges and Future Perspectives

edited by Marco Soligo

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2090 | Submission Open

Keywords: pelvic organ prolapse; urinary incontinence; lower urinary disorders; quality of life; patient-reported outcomes

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Practice and Future Perspectives of Neurological Conditions Caused by Neurodegeneration, 2nd Edition

edited by

Lilla Bonanno

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1927 | Submission Open

Keywords: neurodegenerative diseases; amyotrophic lateral sclerosis; multiple sclerosis; Parkinson's disease; Alzheimer's disease; Huntington's disease; multiple-system atrophy; prion diseases; stroke

(This special issue belongs to the Section Clinical Neurology)

New Insights into Orthopedic Trauma Surgery—Pelvic and Acetabular Fracture Management

edited by Vera Jaecker and

Sven Märdian

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1919 | Submission Open

Keywords: acetabular fractures; pelvic fractures; trauma surgery; intrapelvic approaches; fragility fractures of the pelvis; minimally invasive approaches; new implants; innovations

(This special issue belongs to the Section Orthopedics)

Advances in Echocardiography and Its Clinical Applications

edited by

Simona Sperlongano

submission deadline 30 Jun 2025 | 3 articles | Viewed by 1845 | Submission Open

Keywords: Doppler imaging; speckle tracking echocardiography; myocardial work; intracardiac flow dynamics; three-dimensional echocardiography; stress echocardiography; transoesophageal echocardiography; contrast echocardiography; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Emerging Therapies for Multiple Myeloma

edited by Brea C. Lipe

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1764 | Submission Open

Keywords: multiple myeloma; immunotherapy; targeted therapy; CAR-T cell therapy; new drugs; transplant

(This special issue belongs to the Section Hematology)

Gastroesophageal Cancer: Outcomes and Therapeutic Management

edited by Michael K. Gibson

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1740 | Submission Open

Keywords: gastroesophageal cancer; targeted therapy; circulating tumor DNA; precision medicine; immune checkpoint inhibitors; esophageal cancer; gastric cancer; biomarkers; molecular characterization

(This special issue belongs to the Section Oncology)

Targeted Diagnosis and Advances in the Clinical Application of Infectious Diseases

edited by

José Antonio Mirón-Canelo

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1728 | Submission Open

Keywords: care-associated infections; emerging infections; prevention and control measures and guidelines; prevention and control training

(This special issue belongs to the Section Infectious Diseases)

Recent Advances in Glaucoma Management

edited by Bogomil Voykov

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1637 | Submission Open

Keywords: glaucoma; MIGS; microinvasive glaucoma surgery; quality of life; sustained-release drugs; wound healing modula-tion; intraocular pressure; intraocular pressure-lowering medication; microstent-supported bleb surgery; MIBS; neuroprotection

(This special issue belongs to the Section Ophthalmology)

Advances in Rehabilitation Care for Geriatric Diseases

edited by

Justyna Mazurek

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1623 | Submission Open

Keywords: geriatric rehabilitation; holistic physiotherapy; physical activity; health outcomes; elderly people; geriatric care; chronic disease; health promotion

(This special issue belongs to the Section Clinical Rehabilitation)

Current Clinical Treatments and Challenges for Cardiovascular Diseases

edited by Georgios Bouras and

Christos Kourek

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1560 | Submission Open

Keywords: heart failure; coronary artery disease; atrial fibrillation; cardiomyopathies; hypertension

(This special issue belongs to the Section Cardiovascular Medicine)

Traumatic Brain Injury: Current Treatment and Future Options

edited by

Ismail Zaed

submission deadline 30 Jun 2025 | 3 articles | Viewed by 1551 | Submission Open

Keywords: traumatic brain injury; trauma; biomarkers; post-traumatic outcome; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Current Trends and Future Directions in Plastic and Reconstructive Surgery

edited by Emilio Trignano

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1402 | Submission Open

Keywords: plastic and reconstructive surgery; breast reconstruction; liposuction; tarsal tunnel syndrome; vasoconstriction; pneumomediastinum; abdominal wall surgery; vulvectomy

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Acute Kidney Injury: Latest Advances and Prospects

edited by

Emanuele de Simone

and Kianoush Kashani

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1191 | Submission Open

Keywords: acute kidney injury (AKI); sepsis; septic shock; renal replacement therapy; intensive care; specialized interventions; biomarkers; risk factors; “ Green Practice” ; nephrology; epidemiology; multidisciplinary approach

(This special issue belongs to the Section Nephrology & Urology)

Advancements in Spinal Oncology: The Current Landscape

edited by Aladine Elsamadicy and

Daniel M. Sciubba

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1081 | Submission Open

Keywords: spinal oncology; patient outcomes; primary bone tumor; spine metastases; intradural tumors

(This special issue belongs to the Section Clinical Neurology)

New Insights into Diabetic Foot

edited by Prashanth Vas and

Marco Meloni

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1043 | Submission Open

Keywords: diabetic foot syndrome; diabetic foot infection; diabetic foot osteomyelitis; peripheral arterial disease; ischaemic ulcer; diabetic neuropathy

(This special issue belongs to the Section Endocrinology & Metabolism)

Targeted Treatment of Oral Cancer

edited by

Yasmine Ghantous

and Claudia Malheiros Coutinho-Camillo

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1029 | Submission Open

Keywords: precision medicine; immunotherapy; targeted drugs; combination therapy; tumor immune evasion; clinical trials

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Challenges in Inflammatory Bowel Diseases

edited by Wesley M. Raup-Konsavage

submission deadline 30 Jun 2025 | 1 articles | Viewed by 871 | Submission Open

Keywords: ulcerative colitis; Chron’ s disease; inflammatory bowel disease; colitis-associated cancer; novel pharmaceutics

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Aortic Surgery

edited by

Antonio Fiore

and Joseph Touma

submission deadline 30 Jun 2025 | 2 articles | Viewed by 840 | Submission Open

Keywords: aortic surgery; aortic disease; aortic valve surgery; endovascular treatment; aortic imaging techniques; aortic aneurysm; acute aortic syndrome

(This special issue belongs to the Section Vascular Medicine)

Clinical Advances in Trauma and Orthopaedic Surgery

edited by Valerio Pace and Pierluigi Antinolfi

submission deadline 30 Jun 2025 | 1 articles | Viewed by 780 | Submission Open

Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury

(This special issue belongs to the Section Orthopedics)

Differential Effects of Bariatric Surgery (BS) and Endoscopic Bariatric Therapy (EBT) on Long and Short-Term Metabolic Outcomes

edited by Mohamad Mokadem

submission deadline 30 Jun 2025 | 1 articles | Viewed by 748 | Submission Open

Keywords: obesity; bariatric surgery; endoscopic bariatric therapy; metabolic surgery; weight loss; metabolism; weight management

(This special issue belongs to the Section Endocrinology & Metabolism)

Personalized Diagnosis and Treatment for Intracranial Aneurysm

edited by Nina Zobenica Moore and Mark D. Bain

submission deadline 30 Jun 2025 | 1 articles | Viewed by 688 | Submission Open

Keywords: cerebral aneurysms; personalized medicine; predictive modeling; simulation imaging; subarachnoid hemorrhage; Intracranial Aneurysm

(This special issue belongs to the Section Clinical Neurology)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 30 Jun 2025 | 1 articles | Viewed by 621 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 30 Jun 2025 | 1 articles | Viewed by 565 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Current Concept and Emerging Treatments of Coronary Artery Disease (CAD)

edited by Simone Fezzi and Roberto Scarsini

submission deadline 30 Jun 2025 | 1 articles | Viewed by 412 | Submission Open

Keywords: coronary physiology; intracoronary imaging; imaging-derived computational physiology; drug-coated balloon and bioresorbable scaffolds; virtual PCI; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 30 Jun 2025 | 1 articles | Viewed by 362 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

Neurosurgery: Current Challenges and New Perspectives

edited by Adip G. Bhargav, Paul J. Camarata and Jean-Luc K. Kabangu

submission deadline 30 Jun 2025 | Viewed by 343 | Submission Open

Keywords: neurosurgery; brain tumor; neuromodulation; epilepsy; cerebrovascular; DEI; spine surgery

(This special issue belongs to the Section Clinical Neurology)

Augmented and Artificial Intelligence in Ophthalmology

edited by Tina Felfeli, Edsel B. Ing, David Jose Mathew and Michael Balas

submission deadline 30 Jun 2025 | Viewed by 320 | Submission Open

Keywords: artificial intelligence; ophthalmology; eye health; vision; teleophthalmology

(This special issue belongs to the Section Ophthalmology)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 30 Jun 2025 | Viewed by 307 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Inflammatory Bowel Disease: From Diagnosis to Treatment—2nd Edition

edited by Laura Maria Minordi and Daniela Pugliese

submission deadline 30 Jun 2025 | 1 articles | Viewed by 284 | Submission Open

Keywords: Crohn’ s disease; ulcerative colitis; imaging; endoscopy; complications; advanced therapies; surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis, Treatment and Comorbidities in Chronic Obstructive Pulmonary Disease (COPD): 2nd Edition

edited by Juan Luis Rodriguez Hermosa, José Luis Álvarez-Sala Walther and Myriam Calle Rubio

submission deadline 30 Jun 2025 | Viewed by 266 | Submission Open

Keywords: COPD; diagnosis; comorbidities; respiratory rehabilitation; inhaled therapy; biological therapies

(This special issue belongs to the Section Respiratory Medicine)

The State of Breast Reconstruction: From Surgical Methods to Patient-Reported Outcomes

edited by Geoffroy C. Sisk

submission deadline 30 Jun 2025 | Viewed by 245 | Submission Open

Keywords: breast reconstruction; implant based; autologous tissue; oncoplastic; breast cancer reconstruction; patient-reported outcomes; acellular dermal matrix; prepectoral; lymphedema; microsurgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Novel Diagnostic and Therapeutic Strategies in Vitreoretinal Disease

edited by Jerzy Mackiewicz and

Mateusz Winiarczyk

submission deadline 30 Jun 2025 | Viewed by 239 | Submission Open

Keywords: retinal detachment; vitreoretinal diseases; PPV; vitrectomy; macular edema; uveitis; AMD; retinal imaging; retinal pathology; diabetic retinopathy; optical coherent tomography; OCT

(This special issue belongs to the Section Ophthalmology)

Innovations and Challenges in Cardiovascular Surgery

edited by Marc Leon

submission deadline 30 Jun 2025 | Viewed by 211 | Submission Open

Keywords: cardiovascular surgery; minimally invasive surgery; robotic surgery; hybrid; 3D printing; artificial intelligence; mechanical circulatory support; heart transplantation; valve disease; aortic dissection; ischemic heart disease; heart failure

(This special issue belongs to the Section Cardiovascular Medicine)

New Perspectives in Lumbar Spine Surgery: Treatment and Management

edited by

Giuseppe La Rocca

submission deadline 30 Jun 2025 | Viewed by 209 | Submission Open

Keywords: lumbar surgery; spine surgery; minimally invasive techniques; advanced imaging; surgical innovations; patient outcomes; evidence-based practices; postoperative care; rehabilitation strategies; surgical management

(This special issue belongs to the Section Orthopedics)

New Trends and Challenges in Critical Care Management

edited by

Anna Wrzosek

submission deadline 30 Jun 2025 | Viewed by 201 | Submission Open

Keywords: critical care; intensive care; extracorporeal organ support; mechanical ventilation; personalized medicine; artificial intelligence; infections; antimicrobial resistance; COVID-19

(This special issue belongs to the Section Intensive Care)

Pelvic Organ Prolapse: Clinical Updates and Perspectives

edited by José Antonio García-Mejido

submission deadline 30 Jun 2025 | Viewed by 193 | Submission Open

Keywords: pelvic floor; ultrasound; pelvic organ prolapse; urogynecology; uterine prolapse; cystocele; rectocele; pelvic organ prolapse quantification system

(This special issue belongs to the Section Obstetrics & Gynecology)

Recent Advances in the Pathogenesis and Management of Metabolic Syndrome

edited by

Ishwarlal Jialal

and Sridevi Devaraj

submission deadline 30 Jun 2025 | Viewed by 193 | Submission Open

Keywords: metabolic syndrome; inflammation; oxidative stress; microbiome dysbiosis; metabolomics; epigenetics/genetics

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 30 Jun 2025 | Viewed by 183 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Clinical Advances and Challenges for Endourology

edited by

Carlo Giulioni

and

Daniele Castellani

submission deadline 30 Jun 2025 | Viewed by 182 | Submission Open

Keywords: urolithiasis; upper tract urothelial carcinoma; benign prostatic hyperplasia; minimally invasive surgical therapies

(This special issue belongs to the Section Nephrology & Urology)

Rehabilitation and Conservative Approaches of Orthopaedic and Sports Medicine Injuries

edited by

Cristiano Sconza

and Berardo di Matteo

submission deadline 30 Jun 2025 | Viewed by 180 | Submission Open

Keywords: rehabilitation; sport medicine; conservative treatment; interventional physiatry; sport injuries

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Diagnosis and Treatment of Urological Cancers

edited by Davide Campobasso,

Stefano Puliatti

and

Daniele Amparore

submission deadline 30 Jun 2025 | Viewed by 180 | Submission Open

Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics

(This special issue belongs to the Section Nephrology & Urology)

Colorectal Surgery: Current Practice and Future Perspectives

edited by

Karel Kostev

submission deadline 30 Jun 2025 | Viewed by 178 | Submission Open

Keywords: colorectal surgery; minimal invasive surgery; open surgery; robot assisted surgery; colorectal cancer; stomach cancer; pancreatic cancer; diverticular disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Epidemiology of Skin Diseases: 3rd Edition

edited by Simone Garcovich and

Luca Fania

submission deadline 30 Jun 2025 | Viewed by 168 | Submission Open

Keywords: dermatology and trends; skin diseases and diagnosis; skin diseases and epidemiology; skin neoplasms and diagnosis; skin neoplasms and epidemiology; prevalence; mortality trends; prevention and control; noncommunicable diseases and therapy

(This special issue belongs to the Section Dermatology)

Clinical Updates on Acute Kidney Disease

edited by

Marco Simonini

submission deadline 30 Jun 2025 | Viewed by 166 | Submission Open

Keywords: acute kidney injury; septic shock and acute kidney injury; surgical acute kidney injury; biomarkers; acute kidney injury-to-chronic kidney disease transition; continuous renal replacement therapy; blood purification; kidney damage

(This special issue belongs to the Section Nephrology & Urology)

Displaying special issue 301-350 on page 7 of 27.

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