jcm-logo

Journal Browser

Journal Browser

The Current Status and Future Directions of Pancreatoduodenectomy and Pancreatectomy

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 30 January 2026 | Viewed by 96

Special Issue Editors


E-Mail
Guest Editor
North Bristol NHS Trust & University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK
Interests: pancreatic surgery; hepatobiliary surgery; pancreatic cancer; periampullary cancers; cholangiocarcinoma; biomarkers; surgical oncology

E-Mail Website
Co-Guest Editor
The Pancreato-Biliary Unit, St James’s University Teaching Hospital, Leeds LS9 7TF, UK
Interests: pancreatic cancer; pancreatic surgery; quality assurance; randomised controlled trials

E-Mail Website
Co-Guest Editor
Department of HPB Surgery, University Hospitals Plymouth NHS Trust, Plymouth PL6 8DH, UK
Interests: Image-guided liver and pancreatic surgery; improving safety of pancreatic and liver surgery; identification of early markers of pancreatic cancer

Special Issue Information

Dear Colleagues,

Since the first pancreatic resections were performed towards the end of the 19th century, pancreatic surgery has continued to evolve. Pancreatoduodenectomy and other forms of pancreatectomy remain extremely central to the work of pancreatic surgeons worldwide. Not surprisingly, over the years, the advancement of surgical techniques has produced several variations and modifications of the common and less common pancreatic resections, which have become part of the armamentarium of pancreatic surgeons. In parallel, as pancreatic surgery advances and evidence accumulates, the role and extent of lymphadenectomy in the context of pancreatic resection may be variable according to the underlying indication, while oncological aspects remain crucial to achieve optimal clearance in the case of malignancy as an indication. Furthermore, more recently, minimally invasive techniques and their rapid uptake raise great promise for the future of pancreatic surgery.

In this Special Issue we are seeking valuable contributions in the form of original research, systematic reviews, meta-analyses and comprehensive review articles to enlighten technical and non-technical aspects of pancreatoduodenectomy and other forms of pancreatectomy in the current era, but also to explore the future directions of resectional pancreatic surgery.

Dr. Vasileios K. Mavroeidis
Dr. Samir Pathak
Prof. Dr. Somaiah Aroori
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pancreatic resection types
  • techniques and modifications
  • anastomotic techniques
  • open resection
  • minimally invasive surgery
  • laparoscopic resection
  • robotic resection
  • hybrid resection techniques
  • pancreatic resection post neoadjuvant treatment
  • lymphadenectomy
  • vascular resections
  • organ-sparing procedures
  • radicality
  • indications
  • complications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 633 KiB  
Article
Robotic Versus Hand-Assisted Distal Pancreatectomy: A Comparative Single Center Retrospective Study
by Nabih Essami, Esther Kazlow, Eitan Dines, Aasem Abu Shtaya, Wisam Assaf, Riad Haddad and Ahmad Mahamid
J. Clin. Med. 2025, 14(14), 4919; https://doi.org/10.3390/jcm14144919 - 11 Jul 2025
Abstract
Background: While there is an abundance of comparative studies on open, laparoscopic, and robotic-assisted distal pancreatectomies (RDPs) available in the literature, direct comparisons between RDP and hand-assisted laparoscopic distal pancreatectomy (HALDP) are limited. This study aimed to assess the safety and efficacy [...] Read more.
Background: While there is an abundance of comparative studies on open, laparoscopic, and robotic-assisted distal pancreatectomies (RDPs) available in the literature, direct comparisons between RDP and hand-assisted laparoscopic distal pancreatectomy (HALDP) are limited. This study aimed to assess the safety and efficacy of RDPs in comparison to HALDPs in the treatment of pancreatic lesions. Methods: This study reviewed 97 patients who underwent distal pancreatectomy at Carmel Medical Center between 2008 and 2024. After excluding 40 patients (24 open and 16 pure laparoscopic resections), the final cohort comprised 57 patients: 20 RDPs and 37 HALDPs. The primary outcomes included peri-operative parameters, while secondary outcomes encompassed 90-day morbidity and mortality. Results: RDPs led to significantly longer operative times (3.9 vs. 2.5 h, p < 0.001) but resulted in shorter hospital stays (4.7 vs. 5.8 days, p = 0.02) and a higher number of harvested lymph nodes (11 vs. 5.4, p = 0.01). While clinically significant pancreatic fistula rates were numerically higher in the RDP group (35% vs. 16.2%, p = 0.18), this difference was not statistically significant. Overall, complication rates were comparable (55% vs. 43.2%, p = 0.39). Severe morbidity (Clavien–Dindo ≥ IIIa) was absent in the RDP group compared to 8% in the HALDP group (p = 0.04). No 90-day mortality was observed in either group. Conclusions: This study indicates that although RDP involves longer operative times, it may provide certain advantages for patients, such as shorter hospital stays, better lymph node retrieval, and a notable decrease in postoperative morbidity when compared to HALDP. Larger prospective studies are needed to validate these results and to determine the most effective surgical approach for distal pancreatectomy. Full article
Show Figures

Figure 1

Back to TopTop