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Clinical Management, Diagnosis and Treatment of Thoracic Diseases: 2nd Edition
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Clinical Management, Diagnosis and Treatment of Thoracic Diseases: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Respiratory Medicine".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 294

Special Issue Editors

Dr. Damiano D’Ardes

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Guest Editor
"Clinica Medica" Institute, Department of Medicine and Aging Sciences, "G. D'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy
Interests: cardiovascular risk; lipid metabolism; metabolic diseases; ultrasound
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea Boccatonda

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Guest Editor
Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Via Massarenti n. 9, 40138 Bologna, Italy
Interests: ultrasound; lung disease; hemostasis and thrombosis; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Thoracic diseases continue to be a significant healthcare burden in both medical and surgical disciplines. In recent years, the epidemiology of pulmonary pathologies has continued to evolve, particularly in the realm of infectious and neoplastic diseases. Advances in imaging, molecular diagnostics, and point-of-care technologies have enabled earlier and more precise diagnoses, while novel medical and surgical treatments are reshaping the therapeutic landscape and improving patient outcomes. This second edition of the Special Issue “Clinical Management, Diagnosis and Treatment of Thoracic Diseases” builds upon the success of the first, offering an updated platform on which to explore emerging diagnostic strategies, minimally invasive interventions, and integrated care pathways in pulmonary medicine. It is intended for a broad range of specialists engaged in the management of chest diseases and aims to highlight the latest innovations and evidence-based approaches in this dynamic and rapidly progressing field.

Dr. Damiano D’Ardes
Dr. Andrea Boccatonda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lung
  • thorax
  • pneumonia
  • chest
  • imaging
  • ultrasound

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Published Papers (1 paper)

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Review

25 pages, 1166 KiB  
Review
Beyond Smoking: Emerging Drivers of COPD and Their Clinical Implications in Low- and Middle-Income Countries: A Narrative Review
by Ramona Cioboata, Mara Amalia Balteanu, Denisa Maria Mitroi, Sidonia Catalina Vrabie, Silviu Gabriel Vlasceanu, Gabriela Marina Andrei, Anca Lelia Riza, Ioana Streata, Ovidiu Mircea Zlatian and Mihai Olteanu
J. Clin. Med. 2025, 14(13), 4633; https://doi.org/10.3390/jcm14134633 - 30 Jun 2025
Viewed by 215
Abstract
Chronic obstructive pulmonary disease (COPD) is an escalating global health burden, with a disproportionate impact on low- and middle-income countries (LMICs). Although tobacco smoking is a well-established risk factor, emerging evidence highlights the significant role of non-smoking exposure in driving the prevalence of [...] Read more.
Chronic obstructive pulmonary disease (COPD) is an escalating global health burden, with a disproportionate impact on low- and middle-income countries (LMICs). Although tobacco smoking is a well-established risk factor, emerging evidence highlights the significant role of non-smoking exposure in driving the prevalence of COPD in these regions. This narrative review synthesizes current data on key non-smoking contributors, including household air pollution, ambient urban pollution, occupational exposure, early-life respiratory insults, chronic infections, and socioeconomic adversity. These risk factors are associated with distinct COPD phenotypes, often marked by increased airway inflammation, reduced emphysema, and variable airflow limitation. Such presentations are particularly common among women and younger populations in LMICs. However, diagnostic and therapeutic challenges persist, owing to limited disease awareness, under-resourced health systems, restricted access to essential medications, and financial constraints impacting adherence. Despite the proven effectiveness of non-pharmacological measures and public health interventions, their implementation remains inadequate because of infrastructural and funding limitations. Bridging these gaps requires region-specific clinical guidelines, improved diagnostic infrastructure, expanded access to affordable treatment, and culturally sensitive interventions. Future priorities include identifying robust biomarkers, refining disease definitions to accommodate non-smoking phenotypes, and advancing implementation science to improve interventions. A coordinated, context-aware global response is essential to reduce the growing burden of COPD in LMICs and to ensure equitable respiratory health outcomes. Full article
(This article belongs to the Special Issue Clinical Management, Diagnosis and Treatment of Thoracic Diseases: 2nd Edition)
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