Current Challenges in Inflammatory Bowel Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 966
Special Issue Editor
Special Issue Information
Dear Colleagues,
The multifactorial etiologies of inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), contribute to the difficulties in developing effective treatments. IBD is caused by immunological dysregulation, environmental triggers, and a genetic predisposition, and is also characterized by persistent, recurrent gastrointestinal tract inflammation.
Even with the development novel medications, including immunomodulators, managing and treating IBD still presents many difficulties, particularly due to immunogenicity and variable responsiveness in patients. The variability in disease presentation and development is a significant challenge that makes early diagnosis and individualized treatment more difficult. The intrusive nature of current diagnostic methods, such as endoscopy and imaging, may make it difficult to forecast the severity of the disease or its complications, such as strictures, fistulas, or colorectal cancer. Disparities in care are made worse by the cost of these treatments.
IBD can also lead to increased risk of anxiety, depression, and a lower quality of life. Furthermore, progress toward preventative measures is hampered by a lack of clarity regarding the precise impact of environmental variables and gut bacteria. In this Special Issue, we invite authors to contribute studies around the mechanism of IBD, novel treatments, improving quality of life, and related topics.
Dr. Wesley M. Raup-Konsavage
Guest Editor
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Keywords
- ulcerative colitis
- Chron’s disease
- inflammatory bowel disease
- colitis-associated cancer
- novel pharmaceutics
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