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Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Respiratory Medicine".

Deadline for manuscript submissions: 25 July 2026

Special Issue Editor


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Guest Editor
1. Division of Respiratory, Allergy and Sleep Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
2. Department of Respiratory Diseases, Pontificia Universidad Católica de Chile, Santiago, Chile
Interests: obstructive sleep apnea; sleep disorder breathing; central apnea; precision medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Obstructive sleep apnea (OSA) is a heterogeneous condition with multiple clinical presentations. Current diagnostic metrics for OSA rely predominantly on frequency-based indices, particularly the apnea–hypopnea index (AHI). In recent years, various endotypes (underlying pathophysiological mechanisms) and phenotypes (observable clinical presentations) have been described, revealing different patterns of disease severity that extend beyond the AHI alone.

Recent advances in signal processing of data from sleep studies, combined with a better understanding of the clinical presentation of OSA across the lifespan, provide valuable information for determining which patients are most likely to benefit from continuous positive airway pressure (CPAP) therapy, mandibular advancement devices, pharmacological treatments, surgery, or combination therapies beyond CPAP alone.

This topic/collection aims to review recent updates in the clinical diagnosis and management of OSA, with special interest in novel approaches to identifying and characterizing OSA patients beyond the AHI. We welcome submissions of original research articles and reviews on this topic.

Dr. Gonzalo Labarca
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obstructive sleep apnea
  • sleep disorder breathing
  • central apnea
  • apnea–hypopnea index
  • precision medicine

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Published Papers

This special issue is now open for submission.
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