Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 1
Special Issue Editor
2. Gastroenterology Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy
Interests: gastroparesis; upper gastrointestinal symptoms; gastric pathophysiology; endoscopic therapy; pyloromiotomy
Special Issue Information
Dear Colleagues,
Gastroparesis (GP) is a chronic motility disorder with delayed gastric emptying in the absence of mechanical gastrointestinal (GI) obstruction, leading to recurrent or persistent upper GI symptoms that could affect the patients’ quality of life, resulting in a burden on healthcare costs. Despite renewed research efforts, many open issues still exist. Its pathogenesis is not yet completely clear, being a multifactorial disease with different physiopathological mechanisms contributing to symptoms. Further open issues concern the diagnostic tests that could adequately frame the complex GP pathophysiology and the lack of functional and pathological markers for selecting patients for tailored therapy and predicting therapeutic response. Findings from currently available diagnostic tools could not correlate with the severity of GI symptoms. The spectrum of GP symptoms is still unclear due to its overlap with other GI motility disorders. This uncertain picture reflects the challenging therapeutic management of GP. Recently, new diagnostic tools and the profiling of the GP molecular basis boosted our knowledge of the GP underlying mechanisms. The advancement of interventional upper GI endoscopy has led to treatments addressing presumed underlying pathophysiological mechanisms of GP.
In this Special Issue, we invite authors to submit papers on the emerging insights on GP and advances in endoscopic therapy of GP.
Dr. Sabrina Gloria Giulia Testoni
Guest Editor
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Keywords
- gastroparesis
- gastric dismotility
- gastric emptying
- gastric per-oral miotomy
- pyloromyotomy
- gastric electric stim-ulation
- botulinum toxin
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