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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Technologies to Assist Emergency Medical Care

edited by

Sangsoo Han

and Young Soon Cho

submission deadline 31 Oct 2025 | 1 articles | Viewed by 576 | Submission Open

Keywords: emergency medical services; artificial intelligence in emergency medicine; telemedicine and remote patient monitoring; wearable health technologies; point-of-care diagnostics; automated decision support systems; robotics in emergency medicine; pre-hospital care innovations

(This special issue belongs to the Section Emergency Medicine)

Emerging Diagnostic and Treatment Approaches for Gynecological Cancers

edited by Marco D'Indinosante

submission deadline 31 Oct 2025 | 1 articles | Viewed by 552 | Submission Open

Keywords: gynecologic oncology; surgical gynecology; biomarkers; endometrial carcinoma; ovarian carcinoma; cervical carcinoma

(This special issue belongs to the Section Obstetrics & Gynecology)

Diabetic Retinopathy Screening: Current Advances and Future Options

edited by

Alauddin Bhuiyan

and

Roland Theodore Smith

submission deadline 31 Oct 2025 | 1 articles | Viewed by 520 | Submission Open

Keywords: diabetic retinopathy; diabetic retinopathy screening; retinal imaging; age-related macular degeneration; artificial intelli-gence; image analysis; color fundus photography; optical coherence tomography imaging; telemedicine

(This special issue belongs to the Section Ophthalmology)

Rehabilitation Strategies for Neurological Disorders: Advances and Insights

edited by Delia Cinteză and Mihai Berteanu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 517 | Submission Open

Keywords: neurorehabilitation; physical medicine; virtual reality; AI in rehabilitation medicine; robotic rehabilitation; telerehabilitation; advanced technologies; upper neuromotor lesions; peripheral neuropathies; wearable sensor devices; assessment; goal-setting; individual rehabilitation plan

(This special issue belongs to the Section Clinical Rehabilitation)

Advances and Future Directions in Percutaneous Coronary Intervention (PCI)

edited by Daniele Giacoppo and Antonio Greco

submission deadline 31 Oct 2025 | 1 articles | Viewed by 513 | Submission Open

Keywords: drug-eluting stents; drug-coated balloons; bioresorbable vascular scaffolds; antiplatelet therapy; intravascular ultrasound; optical coherence tomography; quantitative flow ratio; complete revascularization

(This special issue belongs to the Section Cardiology)

Advanced Hepato-Pancreato-Biliary Surgery: Clinical Innovations and Improved Outcomes

edited by Ahmad Mahamid and Riad Haddad

submission deadline 31 Oct 2025 | 1 articles | Viewed by 453 | Submission Open

Keywords: liver surgery; pancreas surgery; biliary surgery; robotic HPB surgery; single incision surgery; prognostic biomarkers; perioperative clinical care; postoperative complications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Trends and Future Prospects in Autoantibodies in Liver Diseases

edited by Takashi Himoto

submission deadline 31 Oct 2025 | 1 articles | Viewed by 359 | Submission Open

Keywords: liver-specific autoantibodies; non-organ-specific autoantibodies; autoimmune liver disease; diagnosis; disease activity; treatment outcome; prognosis; virus-induced autoimmunity; drug-induced autoimmunity

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Complex Spine Surgery: The Road from Childhood to Adults and Future Directions

edited by Jacob M. Buchowski,

Pawel Grabala

and Michael A. Galgano

submission deadline 31 Oct 2025 | Viewed by 318 | Submission Open

Keywords: complex spine; scoliosis; kyphosis; spinal deformities; spinal tumor; spinal reconstruction; sagittal balance; coronal imbalance

(This special issue belongs to the Section Clinical Neurology)

Interstitial Lung Diseases: New Treatments and Future Directions

edited by Justyna Fijołek

submission deadline 31 Oct 2025 | 1 articles | Viewed by 311 | Submission Open

Keywords: Interstitial Lung Disease (ILD); pulmonary fibrosis; orphan lung disease; AAV-ILD; occupational ILD; rheumatic lung disease; treatment strategies; emerging therapies; precision medicine; future directions

(This special issue belongs to the Section Respiratory Medicine)

Current Trends in Hand Surgery

edited by

Alexandre Kaempfen

and Florian Frueh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 253 | Submission Open

Keywords: microsurgery; minimally invasive; arthroscopy; sonography; nerve surgery; joint replacement

(This special issue belongs to the Section Orthopedics)

Current Updates and Advances in Hemodialysis

edited by Edita Žiginskienė

submission deadline 31 Oct 2025 | Viewed by 197 | Submission Open

Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Diagnosis and Treatment of Skin Cancer

edited by

Konstantinos Lallas

and

Aimilios Lallas

submission deadline 31 Oct 2025 | Viewed by 184 | Submission Open

Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis

(This special issue belongs to the Section Oncology)

Clinical Updates in Pediatric Radiology

edited by

Meriam Koob

and

Farnaz Delavari

submission deadline 31 Oct 2025 | Viewed by 169 | Submission Open

Keywords: pediatric radiology; advances in pediatric imaging; pediatric neuroimaging; artificial in-telligence in pediatric imaging; radiomics and machine learning; low-field MRI techniques; magnetic resonance imaging in pediatrics; computed tomography in pediatrics; radiation dose optimization; patient-centred imaging protocols

(This special issue belongs to the Section Clinical Pediatrics)

Preoperative Optimization in Cardiac Surgery

edited by

Jason M. Ali

submission deadline 31 Oct 2025 | Viewed by 156 | Submission Open

Keywords: preoperative optimization; cardiac surgery; risk assessment; comorbid conditions; multidisciplinary collaboration; perioperative risks; cardiovascular evaluation

(This special issue belongs to the Section Cardiology)

Obstructive Sleep Apnea: Latest Advances and Prospects

edited by

Carlos O’Connor Reina

submission deadline 31 Oct 2025 | Viewed by 150 | Submission Open

Keywords: obstructive sleep apnea; sleep medicine; myofunctional therapy; sleep surgery; neurostimulation; personalized treatment; biomarkers; adherence; home sleep testing

(This special issue belongs to the Section Otolaryngology)

Recent Advances in the Epidemiology of Infectious Diseases: A Clinical Perspective

edited by

Yazan A. Al-Ajlouni

submission deadline 31 Oct 2025 | Viewed by 147 | Submission Open

Keywords: epidemiology of infectious diseases; global health and infectious diseases; hospital-acquired infections (HAIs); infection control; novel treatments; vaccine effectiveness

(This special issue belongs to the Section Epidemiology & Public Health)

Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis

edited by Dong-Ho Kang

submission deadline 31 Oct 2025 | Viewed by 145 | Submission Open

Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning

(This special issue belongs to the Section Orthopedics)

Immunotherapy of Hematological Malignancies: The State of the Art

edited by

Anca Colita

and

Romeo Gabriel Mihaila

submission deadline 31 Oct 2025 | Viewed by 141 | Submission Open

Keywords: antibody-drug conjugates; bispecific antibodies; chimeric antigen receptor-engineered natural killer cell; chimeric antigen receptor T-cells; cytokine release syndrome; immune checkpoint in-hibitors; immunosuppression; immunotherapy; monoclonal antibodies; neurotoxicities

(This special issue belongs to the Section Hematology)

Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management

edited by

Andreas Mitsis

and

Nikolaos Kadoglou

submission deadline 31 Oct 2025 | Viewed by 132 | Submission Open

Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management

(This special issue belongs to the Section Cardiology)

Intramedullary Nail of Long Bone Fractures: Treatments, Outcomes, and Staying out of Trouble

edited by Robert D. Zura and Jessica C. Rivera

submission deadline 31 Oct 2025 | Viewed by 131 | Submission Open

Keywords: intramedullary nail; intramedullary fixation; fracture fixation; femur fracture; tibia fracture; orthopedic implant; fracture healing

(This special issue belongs to the Section Orthopedics)

Updates in Diabetes and Obesity in Reproductive Health

edited by

Amihai Rottenstreich

and Giulia Barda

submission deadline 31 Oct 2025 | Viewed by 129 | Submission Open

Keywords: obesity; diabetes; reproductive health; childbearing age; pregnancy

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Recent Developments in Reproductive Endocrinology

edited by Birute Žilaitiené and Jonas Čeponis

submission deadline 31 Oct 2025 | Viewed by 128 | Submission Open

Keywords: hypogonadism; infertility; sex hormone deficiency; reproductive endocrinology; sexual health; assisted reproduction

(This special issue belongs to the Section Endocrinology & Metabolism)

New Developments in Coronary Interventional Therapy

edited by

Chadi Alraies

submission deadline 31 Oct 2025 | Viewed by 120 | Submission Open

Keywords: high risk PCI; optical coherence tomography; chronic total occlusions; bifurcation lesions; left main stem disease; multivessel coronary artery disease

(This special issue belongs to the Section Cardiology)

Skin Cancers: Update on Clinical Treatment and Management

edited by Nazzaro Gianluca

submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open

Keywords: basal cell carcinoma; squamous cell carcinoma; melanoma; skin cancers; dermoscopy; ultrasonography; immunotherapy; biomarker; prevention; diagnosis; treatment; innovative treatments; prognosis

(This special issue belongs to the Section Dermatology)

Neuropathic Pain: From Prevention to Diagnosis and Management

edited by Enrico Martin

submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open

Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms

(This special issue belongs to the Section Clinical Neurology)

Endometriosis and Endometrial Cancer: Challenge and Clinical Management

edited by

Bogdan Obrzut

, Tomasz Kluz and Bernhard Krämer

submission deadline 31 Oct 2025 | Viewed by 112 | Submission Open

Keywords: endometriosis; endometrial cancer; non-invasive diagnosis; molecular profiling; surgical techniques; medical treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Urologic Neoplasms: Recent Advances and Future Perspectives

edited by

Dorit E. Zilberman

submission deadline 31 Oct 2025 | Viewed by 108 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; immunotherapy; chemotherapy; radiotherapy; prostate cancer; renal cancer; bladder cancer; upper urinary tract neoplasm; testicular cancer; penile cancer

(This special issue belongs to the Section Oncology)

Challenges and Opportunities in Bariatric Surgery

edited by

Francisco Guzman Pruneda

and Umashankkar Kannan

submission deadline 31 Oct 2025 | Viewed by 98 | Submission Open

Keywords: bariatric surgery; DVT/VTE; bleeding; complications; prophylaxis

(This special issue belongs to the Section General Surgery)

PET/CT Imaging in Oncology: Clinical Updates and Prospects

edited by Ahmad Shariftabrizi

submission deadline 5 Nov 2025 | 1 articles | Viewed by 194 | Submission Open

Keywords: new radiotracers; PET radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy outcome prediction; PET physics; normal tissue PET/CT; synchronous malignancies

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Rehabilitation Medicine and Clinical Research: From Diagnosis to Therapeutic Interventions

edited by

Yazan A. Al-Ajlouni

submission deadline 6 Nov 2025 | Viewed by 208 | Submission Open

Keywords: rehabilitation medicine; clinical research; therapeutic interventions; diagnosis; physical therapy; occupational therapy; neurorehabilitation; musculoskeletal rehabilitation; cardiac rehabilitation; functional recovery; assistive technologies; patient-centered care; outcome measures; rehabilitation innovations; multidisciplinary approaches

(This special issue belongs to the Section Clinical Rehabilitation)

Potential Cures of Alzheimer's Dementia

edited by

Jeffrey Fessel

submission deadline 10 Nov 2025 | 4 articles | Viewed by 13090 | Submission Open

Keywords: Alzheimer’ s dementia; cure; therapeutic approaches; clinical assessment; diagnosis; treatment

(This special issue belongs to the Section Mental Health)

New Insights into Exercise Intervention for Aging and Geriatric Diseases: 2nd Edition

edited by

Hyuntae Park

submission deadline 10 Nov 2025 | 6 articles | Viewed by 7533 | Submission Open

Keywords: exercise intervention; exercise adherence and feasibility; digital exercise therapy; digital therapeutics; mild cognitive impairment; osteoporosis; dementia; sarcopenia; frailty; depression; sleep disorder; obesity; geriatric disease

(This special issue belongs to the Section Sports Medicine)

Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment

edited by

Georgios Floros

submission deadline 10 Nov 2025 | 3 articles | Viewed by 6452 | Submission Open

Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry

(This special issue belongs to the Section Mental Health)

Gastroesophageal Cancer: Advances in Clinical Diagnosis and Management

edited by

Tania Triantafyllou

and Maximos Frountzas

submission deadline 10 Nov 2025 | 4 articles | Viewed by 3008 | Submission Open

Keywords: gastroesophageal cancer; endoscopic therapy; minimally invasive surgery; multimodality treatment; immunotherapy

(This special issue belongs to the Section Oncology)

Clinical Advances in Trauma and Emergency Medicine

edited by Viktoria Bogner-Flatz

submission deadline 10 Nov 2025 | 4 articles | Viewed by 2571 | Submission Open

Keywords: resuscitation; trauma emergency management; disaster response; mild traumatic brain injury emergency management; critical emergency care

(This special issue belongs to the Section Emergency Medicine)

Pediatric Neuromuscular Diseases: Current Concepts, Challenges and Opportunities (Second Edition)

edited by Nina Barišić

submission deadline 10 Nov 2025 | Viewed by 149 | Submission Open

Keywords: neuromuscular disorders (NMD); pediatric; genetic NMD; chronic demyelinating polyneuropathy; juvenile myasthenia gravis; ethics; health economics; next generation sequencing (NGS); diagnosis; prenatal; fetal; disease modifying therapy; immunotherapy; guidelines

(This special issue belongs to the Section Clinical Pediatrics)

New Advances in Myasthenia Gravis

edited by Shingo Konno

submission deadline 13 Nov 2025 | 2 articles | Viewed by 1717 | Submission Open

Keywords: myasthenia gravis; clinical trials; translational research; drug repurposing; biological markers; experimental autoimmune myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Cardiovascular Interventions

edited by

Tomasz Tokarek

submission deadline 14 Nov 2025 | 7 articles | Viewed by 5956 | Submission Open

Keywords: coronary artery disease; myocardial infarction; cardiovascular imaging; microvascular disease; heart failure; atrial fibrillation; ventricular arrhythmias; cardiac implantable electronic device; valvular heart disease and treatment; peripheral arterial disease

(This special issue belongs to the Section Cardiology)

Advances in Catheter Ablation: Current Challenges and Future Perspectives

edited by

Gabriel Cismaru

and Raluca Tomoaia

submission deadline 15 Nov 2025 | 2 articles | Viewed by 2255 | Submission Open

Keywords: catheter ablation; three-dimensional mapping; arrhythmia; wolf– parkinson– white syndrome; atrial fibrillation

(This special issue belongs to the Section Cardiology)

New Advances in Wound Healing and Skin Wound Treatment

edited by Hajime Matsumura

submission deadline 15 Nov 2025 | 2 articles | Viewed by 2034 | Submission Open

Keywords: trauma wound; burns; chronic wound; DFU; VLU; ischemic wound; regenerative medicine in wound care; debridement; biofilm; wound dressing; antimicrobial treatment

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Applications of Artificial Intelligence (AI) in Surgery: Future Trends and Challenges

edited by

Michał H. Strzelecki

and

Rafał Obuchowicz

submission deadline 15 Nov 2025 | 1 articles | Viewed by 888 | Submission Open

Keywords: artificial intelligence; surgical planning; surgical medical robots; machine learning in surgery; AI-supported post-operative care

(This special issue belongs to the Section General Surgery)

Clinical Update in Pulmonary Rehabilitation

edited by Akira Tamaki

submission deadline 15 Nov 2025 | Viewed by 147 | Submission Open

Keywords: pulmonary rehabilitation; chronic obstructive pulmonary disease; interstitial lung disease; sarcopenia; respiratory sarcopenia; respiratory muscle training; nutritional intervention

(This special issue belongs to the Section Respiratory Medicine)

Neuroendocrine Neoplasms: Epidemiology, Clinical Management, and Emerging Therapies

edited by

H. Christian Weber

submission deadline 15 Nov 2025 | Viewed by 124 | Submission Open

Keywords: neuroendocrine neoplasms (NENs); epidemiology; biomarkers for NENs; targeted therapies for NENs; carcinoid syndrome; precision medicine; gastrointestinal NENs; advanced endoscopic approaches to NEN treatment; imaging modalities for NENs; survival risk factors in NENs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Mechanisms and Management of Intracerebral Hemorrhage

edited by Emanuela Crobeddu

submission deadline 15 Nov 2025 | Viewed by 67 | Submission Open

Keywords: intracerebral hemorrhage; arteriovenous malformation (AVM); dural arteriovenous fistula (DAVF); cavernoma; neuroinflammation; blood– brain barrier; hematoma evacuation; neuroprotection; imaging technologies; vascular lesions

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Vascular and Endovascular Surgery

edited by Toshifumi Kudo

submission deadline 20 Nov 2025 | 11 articles | Viewed by 12424 | Submission Open

Keywords: aortic aneurysm; peripheral arterial disease; chronic limb-threatening ischemia; endovascular aneurysm repair; endovascular treatment; non-invasive blood flow measurements; varicose veins; deep venous thrombosis

(This special issue belongs to the Section Vascular Medicine)

Advances in Trauma and Orthopedic Surgery: 2nd Edition

edited by

Christian von Rüden

submission deadline 20 Nov 2025 | 10 articles | Viewed by 10742 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Thromboembolic Disease and Antithrombotic Therapy

edited by Prahlad Ho

submission deadline 20 Nov 2025 | 6 articles | Viewed by 9520 | Submission Open

Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein thrombosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Virchow’ s triad; post thrombotic syndrome

(This special issue belongs to the Section Hematology)

Association Between Sleep Disorders and Diabetes

edited by

Patrizio Tatti

and Desiderio Passàli

submission deadline 20 Nov 2025 | 2 articles | Viewed by 9202 | Submission Open

Keywords: diabetes; OSAS; complications; insulin; resistance

(This special issue belongs to the Section Endocrinology & Metabolism)

Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management

edited by Emelina Stambolliu and Antonios A. Argyris

submission deadline 20 Nov 2025 | 5 articles | Viewed by 7541 | Submission Open

Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds

(This special issue belongs to the Section Vascular Medicine)

Complex Orthopedic Trauma: Diagnosis, Treatment, Managing Complications and Rehabilitation

edited by Philip-Christian Nolte and Benedict Swartman

submission deadline 20 Nov 2025 | 5 articles | Viewed by 5276 | Submission Open

Keywords: orthopedic trauma; fracture; complications; infection; bone; rehabilitation

(This special issue belongs to the Section Orthopedics)

Displaying special issue 701-750 on page 15 of 28.

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