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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards

edited by

Mara Carsote

and

Claudiu Nistor

submission deadline 30 Nov 2025 | 1 articles | Viewed by 433 | Submission Open

Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography

(This special issue belongs to the Section Endocrinology & Metabolism)

New Updates in Pediatric Gastroenterology

edited by

Laura Trandafir

, Alina Stanescu-Popp and Oana Belei

submission deadline 30 Nov 2025 | Viewed by 227 | Submission Open

Keywords: pediatric gastroenterology and hepatology; inflammatory bowel disease; celiac disease; gastrointestinal diseases; esophageal diseases; endoscopy; gut microbiome; inflammatory bowel disease; functional GI disorders; nutritional management; precision medicine; gut– brain axis; transitional care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Diagnosis and Treatment of Ocular Surface Tumors and Diseases

edited by Sotiria Palioura, Carolina L. Mercado and

Jaime D. Martinez

submission deadline 30 Nov 2025 | Viewed by 205 | Submission Open

Keywords: ocular surface diseases; anterior segment imaging; chemotherapeutics; immunomodulatory agents; minimally invasive surgical techniques

(This special issue belongs to the Section Ophthalmology)

Clinical Application of Knee Arthroscopy

edited by

Francesco Bosco

and Alessandro Carrozzo

submission deadline 30 Nov 2025 | Viewed by 192 | Submission Open

Keywords: knee surgery; arthroscopy; orthopedics; sport medicine; clinical outcomes; ligament reconstruction; meniscal repair; cartilage; postoperative rehabilitation; knee joint; tissue repair; joint preservation

(This special issue belongs to the Section Orthopedics)

Exploring Cardiomyopathy: Comprehensive Guide to Causes, Symptoms and Care

edited by

Keiichi Hirono

submission deadline 30 Nov 2025 | Viewed by 185 | Submission Open

Keywords: cardiomyopathy; heart failure; genetics; hypertrophic cardiomyopathy; dilated cardiomyopathy; left ventricular noncompaction; pediatric cardiomyopathies; cardiac imaging

(This special issue belongs to the Section Cardiology)

Current Challenges in Orthopedic Trauma Surgery

edited by Pietro Maniscalco and Fabrizio Quattrini

submission deadline 30 Nov 2025 | Viewed by 156 | Submission Open

Keywords: hip replacement; knee replacement; shoulder replacement; ankle replacement; trauma surgery; femur; future chal-lenges; surgical innovations

(This special issue belongs to the Section Orthopedics)

Anesthesia and Perioperative Management of Organ Transplants

edited by

Uzung Yoon

and Ji-Hye Kwon

submission deadline 30 Nov 2025 | Viewed by 152 | Submission Open

Keywords: liver transplantation; coagulation; reperfusion syndrome; perioperative evaluation; coronary artery disease; CDC; DBD; living donor liver transplant; pulmonary evaluation; hepatorenal syndrome; portopulmonary hypertension

(This special issue belongs to the Section Anesthesiology)

New Insights into Acne Vulgaris Treatment and Management Strategies

edited by Jo Linda Maria Sinagra

submission deadline 30 Nov 2025 | Viewed by 144 | Submission Open

Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic

(This special issue belongs to the Section Dermatology)

Challenges in the Diagnosis and Treatment of Glaucoma

edited by

Abdelaziz Abdelaal

submission deadline 30 Nov 2025 | Viewed by 139 | Submission Open

Keywords: glaucoma diagnosis; glaucoma progression; glaucoma biomarkers; intraocular pressure (IOP) management; corneal hysteresis; machine learning in glaucoma detection; neuroprotection in glaucoma; surgery and laser therapy

(This special issue belongs to the Section Ophthalmology)

Technology and Innovations in Microsurgical Reconstruction: Bridging Challenges in Breast, Lymphatic, and Limb Reconstruction

edited by Gordon K. Lee,

Dung Nguyen

and

Sik Namgoong

submission deadline 30 Nov 2025 | Viewed by 138 | Submission Open

Keywords: microsurgery; breast reconstruction; limb reconstruction; perforator flaps; super microsurgery; surgical innovation; reconstructive surgery; lymphedema; tissue engineering; diabetic foot reconstruction; wound healing; cell therapy

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Spine Surgery Innovations: Clinically Advanced Treatment and Technologies

edited by Jang W. Yoon

submission deadline 30 Nov 2025 | Viewed by 131 | Submission Open

Keywords: minimally invasive spine surgery; artificial intelligence; wearable biometrics; big data; smartphone accelerometer

(This special issue belongs to the Section Orthopedics)

Clinical Research in Vascular Access Devices

edited by

Antonio Gidaro

submission deadline 30 Nov 2025 | Viewed by 128 | Submission Open

Keywords: short peripheral catheters; long peripheral catheters; midline; peripherally inserted central catheters (PICCs); femoral-inserted central catheters (FICCs); centrally inserted central catheters (CICCs); totally implantable venous access devices (TIVAD); catheter-related bloodstream infection (CRBSI); catheter-associated bloodstream infection (CABSI); central line-associated bloodstream infection (CLABSI); catheter-related thrombosis (CRT); fibroblastic sleeve; infiltration; extravasation

(This special issue belongs to the Section Vascular Medicine)

Role of Platelet in Inflammation, Infection, and Immune Response

edited by

Amir Houshang Shemirani

submission deadline 30 Nov 2025 | Viewed by 127 | Submission Open

Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response

(This special issue belongs to the Section Hematology)

Minimally Invasive Gastrointestinal Surgery: Clinical Advances and Prospects

edited by Jun Suh Lee

submission deadline 30 Nov 2025 | Viewed by 126 | Submission Open

Keywords: minimally invasive surgery; gastrointestinal surgery; laparoscopic surgery; robotic surgery; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Key Quality Indicators in Diagnosis and Treatment of Respiratory Diseases

edited by

Fotios Sampsonas

submission deadline 30 Nov 2025 | Viewed by 126 | Submission Open

Keywords: key quality indicators; respiratory disorders; audit; quality improvement; real-life data

(This special issue belongs to the Section Respiratory Medicine)

Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities

edited by Gian Marco Prucher,

Andrea Cassoni

and Francesco Arcuri

submission deadline 30 Nov 2025 | Viewed by 121 | Submission Open

Keywords: head and neck reconstruction; facial fractures; minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillo facial trauma and deformities

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Percutaneous Coronary Intervention: Latest Advances and Future Prospects

edited by

Alessandro Mandurino-Mirizzi

submission deadline 30 Nov 2025 | Viewed by 114 | Submission Open

Keywords: percutaneous coronary intervention; coronary artery disease; intravascular imaging; intracoronary physiology; high-risk percutaneous coronary intervention; calcified coronary stenosis; chronic total occlusion; bifurcation disease

(This special issue belongs to the Section Cardiology)

Novel Insights into the Clinical Management of Retinal Detachment

edited by Francesco Sabatino

submission deadline 30 Nov 2025 | Viewed by 103 | Submission Open

Keywords: retinal detachment; oil toxicity; gas tamponade; pars plana vitrectomy; scleral buckle; pneumatic retinopexy; surgical techniques; retinal imaging; retinal displacement

(This special issue belongs to the Section Ophthalmology)

Interventional Cardiology: Clinical Advances and Future Perspectives

edited by Antonio Landi and

Andrea Milzi

submission deadline 30 Nov 2025 | Viewed by 103 | Submission Open

Keywords: percutaneous coronary intervention; myocardial infarction; interventional cardiology; cardiac catheterization; coronary artery disease; antithrombotic therapy; intravascular imaging; acute coronary syndrome; chronic coronary syndrome

(This special issue belongs to the Section Cardiology)

Clinical Advances in Neuroprognostication and Outcome Prediction After Cardiac Arrest

edited by

Erik Roman-Pognuz

submission deadline 30 Nov 2025 | Viewed by 92 | Submission Open

Keywords: neuroprognostication; cardiac arrest; neurological outcome prediction; biomarkers in brain injury; multimodal prog-nostic tools; EEG monitoring; somatosensory evoked potentials (SSEPs); magnetic resonance imaging (MRI) in prognos-tication; post-cardiac arrest care; hypoxic– ischemic brain injury; withdrawal of life-sustaining treatment (WLST); inten-sive care prognostic strategies

(This special issue belongs to the Section Cardiovascular Medicine)

Kidney Transplantation: Recent Advances and Challenges

edited by Jose Torrealba

submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open

Keywords: kidney allograft; pathology; HLA and antibodies; management

(This special issue belongs to the Section Nephrology & Urology)

Thrombotic Risk and Its Management Across Diverse Clinical Settings

edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu

submission deadline 30 Nov 2025 | Viewed by 77 | Submission Open

Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers

(This special issue belongs to the Section Hematology)

Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges

edited by Mohamed Farag

submission deadline 30 Nov 2025 | Viewed by 70 | Submission Open

Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in the Management and Treatment of Obesity

edited by

Francesca Battista

submission deadline 5 Dec 2025 | 1 articles | Viewed by 2729 | Submission Open

Keywords: obesity; therapy; weight loss; diet; surgery; exercise; personalized medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

AI in Maternal Fetal Medicine and Perinatal Management

edited by Ariel Many

submission deadline 5 Dec 2025 | 1 articles | Viewed by 564 | Submission Open

Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction

(This special issue belongs to the Section Obstetrics & Gynecology)

Comprehensive Approaches in Plastic and Reconstructive Surgery

edited by Michael Alfertshofer

submission deadline 7 Dec 2025 | 3 articles | Viewed by 3271 | Submission Open

Keywords: plastic surgery; reconstructive surgery; regenerative medicine; advanced surgical planning; trauma reconstruction; patient-specific solutions; multidisciplinary care

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Challenges in Obstetrics and Gynecology: Interactions Between Gynecological and Obstetric Disorders, Quality of Life, and Mental Health in Women

edited by

Ernesto González-Mesa

and Daniel María Lubián López

submission deadline 10 Dec 2025 | 5 articles | Viewed by 5179 | Submission Open

Keywords: perinatal mental health; gynecological disorders; sexual disorders; women’ s quality of life; obstetric complications; women’ s health; women’ s psychological well-being

(This special issue belongs to the Section Obstetrics & Gynecology)

State of the Art: Updates in Preterm Labor and Preterm Birth

edited by

Eran Bornstein

and Moti Gulersen

submission deadline 10 Dec 2025 | 4 articles | Viewed by 4261 | Submission Open

Keywords: prenatal diagnosis; preterm birth; antenatal corticosteroids; cerclage; multiple gestations

(This special issue belongs to the Section Obstetrics & Gynecology)

Kidney Transplantation and Rehabilitation: Current Updates and Perspectives

edited by Zoltán Sándor

submission deadline 10 Dec 2025 | 2 articles | Viewed by 4039 | Submission Open

Keywords: chronic kidney disease; kidney transplantation; transplant rehabilitation; transplant care; physical therapy; occupational therapy; intervention; recovery; quality of life; aftercare

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Prevention, Diagnosis, and Rehabilitation of Sports Injuries

edited by Kevin Laudner

submission deadline 10 Dec 2025 | 2 articles | Viewed by 3248 | Submission Open

Keywords: orthopedics; prevention; rehabilitation; management; sports injuries

(This special issue belongs to the Section Sports Medicine)

Cardiac Arrhythmias: Current Status and Future Directions

edited by

Jackson J. Liang

submission deadline 10 Dec 2025 | 1 articles | Viewed by 2849 | Submission Open

Keywords: ventricular tachycardia; atrial fibrillation; catheter ablation; novel therapies; complex arrhythmias

(This special issue belongs to the Section Cardiology)

Latest Research on Male Infertility

edited by

Manesh Kumar Panner Selvam

submission deadline 10 Dec 2025 | Viewed by 360 | Submission Open

Keywords: testis; sperm; seminal plasma; spermatogenesis; fertilization; omics; proteomics; oxidative stress; sperm DNA fragmentation; varicocele; male infertility; testicular cancer; infertility management; ART

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Clinical Advances in Arthroscopic Shoulder Surgery

edited by Anup Ajit Shah, Michael J. O’Brien and Asheesh Bedi

submission deadline 10 Dec 2025 | Viewed by 352 | Submission Open

Keywords: rotator cuff; biologic tuberoplasty; lower trapezius tendon transfer; arthroscopic Latarjet; arthroscopic bone block; augmentation of the cuff

(This special issue belongs to the Section Orthopedics)

Innovative Endodontics

edited by

Federico Foschi

submission deadline 10 Dec 2025 | Viewed by 65 | Submission Open

Keywords: regenerative endodontics; bioceramics; guided endodontics; AI in endodontics; pericervical dentine; reduced taper; irrigation adjuvant; pulp regeneration

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates on Geriatric Oncology

edited by Cherif N. Boutros

submission deadline 12 Dec 2025 | Viewed by 87 | Submission Open

Keywords: geriatric oncology; cancer in elderly; geriatric cancer care; frailty; access to cancer care

(This special issue belongs to the Section Geriatric Medicine)

Physical Activity, Exercise and Health: Clinical Management and Research

edited by

Do-yeon Kim

Dae Yun Seo

and

Ju-yong Bae

submission deadline 15 Dec 2025 | 4 articles | Viewed by 5500 | Submission Open

Keywords: physical activity; exercise; exercise physiology; exercise prescription; aging; women’ s health; chronic disease

(This special issue belongs to the Section Epidemiology & Public Health)

Aortic Pathologies: Aneurysm, Atherosclerosis and More

edited by Alexander Gombert and Panagiotis Doukas

submission deadline 15 Dec 2025 | 4 articles | Viewed by 5316 | Submission Open

Keywords: aorta; aortic aneurysm; thoracoabdominal aortic aneurysm; fenestrated endovascular aortic repair (FEVAR); branched endovascular aortic repair (BEVAR); spinal cord ischemia; coral reef aorta; surgery; endovascular aortic surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Coronary Heart Disease: Causes, Diagnosis and Management

edited by

Andrea Denegri

submission deadline 15 Dec 2025 | 3 articles | Viewed by 4908 | Submission Open

Keywords: coronary heart disease; coronary revascularization; coronary artery disease; ischemic heart disease; atherosclerosis

(This special issue belongs to the Section Cardiology)

Evidence-Based Clinical Management of Orthopaedic Trauma: 25 Years in Retrospect, and a Forecast of 25 Years to Come

edited by Dirk Stengel and

Paul Alfred Grützner

submission deadline 15 Dec 2025 | 3 articles | Viewed by 3632 | Submission Open

Keywords: evidence-based medicine; orthopaedic surgery; clinical trials; systematic reviews; patient outcomes; multiple trauma; artificial intelligence; injuries

(This special issue belongs to the Section Orthopedics)

Spine Surgery: Clinical Advances and Future Directions

edited by

Seung-kook Kim

and Eun-Sang Kim

submission deadline 15 Dec 2025 | 4 articles | Viewed by 3574 | Submission Open

Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain

(This special issue belongs to the Section Clinical Neurology)

Neural Application of Artificial Intelligence in Clinical Neuroscience

edited by Saurabh J. Singhal

submission deadline 15 Dec 2025 | 2 articles | Viewed by 2054 | Submission Open

Keywords: artificial intelligence (AI); clinical neuroscience; neuroimaging; brain– computer interfaces (BCIs); neuroprosthetics; EEG/EMG analysis; robotic surgery; deep brain stimulation (DBS); drug discovery; telemedicine; neurorehabilitation; stroke detection; Alzheimer’ s disease; brain tumors; seizure prediction

(This special issue belongs to the Section Clinical Neurology)

Clinical Advancements in Intraocular Lens Power Calculation Methods

edited by

Christoph Martin Lwowski

and Thomas Kohnen

submission deadline 15 Dec 2025 | 1 articles | Viewed by 1017 | Submission Open

Keywords: emmetropia; IOL power calculation; effective lens position; refractive lens exchange; IOL; refractive surgery; biometry

(This special issue belongs to the Section Ophthalmology)

Cancers of the Pelvic Organs: Contemporary Management and Actions for Improving Patients’ Quality of Life: 2nd Edition

edited by

Agnieszka Mazur-Bialy

and

Marcin Opławski

submission deadline 15 Dec 2025 | 1 articles | Viewed by 941 | Submission Open

Keywords: gynecological cancers; e.g.; endometrial; cervical; ovarian; and vulvar cancer; urogenital tract cancers in men; e.g.; bladder; prostate; penis; and testicular cancer; gastrointestinal cancers; complications of oncological treatment; e.g.; pelvic floor disfunction: incontinence and POP; patients’ quality of life and possibilities of its improvement; oncofertility; physiotherapy; oncology treatment (modern surgical approach; including robotics; chemotherapy; radiotherapy; immunotherapy; targeted therapy); biological basis of pathogenesis and cancer progression; biological markers; anticancer agents; cancer prophylaxis and prevention— current trends and opportunities

(This special issue belongs to the Section Oncology)

Rheumatoid Arthritis: Challenges, Innovations and Outcomes

edited by

Marco Fornaro

submission deadline 15 Dec 2025 | 1 articles | Viewed by 810 | Submission Open

Keywords: rheumatoid arthritis; pathogenesis; treatments; outcomes; autoimmunity

(This special issue belongs to the Section Immunology)

Latest Advances in Pediatric Surgery

edited by Francesco Macchini and Andrea Zanini

submission deadline 15 Dec 2025 | 1 articles | Viewed by 706 | Submission Open

Keywords: pediatric surgery; innovations; fluorescence-guided surgery; pediatric robotic surgery; minimally invasive surgery

(This special issue belongs to the Section General Surgery)

Arthroplasty: Advances in Surgical Techniques and Patient Outcomes—2nd Edition

edited by Senthil Sambandam

submission deadline 15 Dec 2025 | 1 articles | Viewed by 703 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; hip fractures; arthroplasty; osteoarthritis; knee arthroscopy; joint replacement

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Cardio-Rheumatology

edited by

Sophie I. Mavrogeni

submission deadline 15 Dec 2025 | 1 articles | Viewed by 680 | Submission Open

Keywords: cardio-rheumatology; autoimmune diseases; cardiac imaging; cardiovascular disease; autoimmune rheumatic diseases

(This special issue belongs to the Section Cardiology)

Cataract and Refractive Surgery and Intraocular Lens Implantation: Clinical Advances and Perspectives

edited by Janusz Skrzypecki

submission deadline 15 Dec 2025 | Viewed by 575 | Submission Open

Keywords: cataract surgery; intraocular lens power calculation; intraocular lenses; EDoF IOL; multifocal IOL; monofocal IOL; laser refractive surgery

(This special issue belongs to the Section Ophthalmology)

Key Advances in the Treatment of the Critically Ill: 3rd Edition

edited by

Spyros D. Mentzelopoulos

submission deadline 15 Dec 2025 | 1 articles | Viewed by 494 | Submission Open

Keywords: respiration; artificial ventilation; prone positioning; respiratory distress syndrome; respiratory insufficiency; cardiac arrest; induced hypothermia; amiodarone; vasopressin; steroids; epinephrine; trauma; injuries; tranexamic acid; sepsis; antibiotics; extracorporeal membrane oxygenation; extracorporeal CPR; blood purification

(This special issue belongs to the Section Intensive Care)

Emergency Surgery: Clinical Updates and New Perspectives

edited by

Bruno Cirillo

submission deadline 15 Dec 2025 | 1 articles | Viewed by 487 | Submission Open

Keywords: emergency surgery; trauma surgery; acute abdomen; hernia emergencies; surgical decision making; perioperative care; damage control surgery; emergency management; critical care surgery; multidisciplinary approach

(This special issue belongs to the Section Emergency Medicine)

Displaying special issue 701-750 on page 15 of 30.

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