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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Neurological Rehabilitation: Innovations and Clinical Insights

edited by

Anna Berardi

submission deadline 31 Aug 2025 | Viewed by 134 | Submission Open

Keywords: rehabilitation; neurology; assessment; occupational therapy; disability; inclusion

(This special issue belongs to the Section Clinical Neurology)

Understanding of the Aortic Organ: Pathophysiology, Diagnosis, Treatment and Challenges

edited by Andrea De Martino,

Antonio Salsano

and Francesco Santini

submission deadline 31 Aug 2025 | Viewed by 124 | Submission Open

Keywords: aorta; risk factors; biomarkers; aortic imaging; aortic pathology; aortic surgery; endovascular treatment

(This special issue belongs to the Section Cardiology)

Obesity Surgery—State of the Art

edited by Anna Casajoana

submission deadline 31 Aug 2025 | Viewed by 120 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; diabetes mellitus type 2; GLP-1

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Applications of Cardiac Imaging: 2nd Edition

edited by Maria Concetta Pastore

submission deadline 31 Aug 2025 | Viewed by 106 | Submission Open

Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Cardiac Arrest Research: Neuroprognostication and Improving Outcomes

edited by

Jae Hoon Lee

and Jin-hong Min

submission deadline 31 Aug 2025 | Viewed by 91 | Submission Open

Keywords: cardiac arrest; prognosis; hypothermia; induced; resuscitation; magnetic resonance imaging; electroencephalography; blood pressure; hypoxia-ischemia; brain; extracorporeal membrane oxygenation

(This special issue belongs to the Section Cardiovascular Medicine)

Minimally Invasive Approaches to Urolithiasis: Current Evidence

edited by

Massimiliano Creta

submission deadline 31 Aug 2025 | Viewed by 89 | Submission Open

Keywords: extracorporeal shock wave lithotripsy; lasers; percutaneous lithotripsy; robotic surgery; ureteroscopy; urolithiasis

(This special issue belongs to the Section Nephrology & Urology)

Evidence-Based Physiotherapy: Prospects and Challenges

edited by Roman Nowobilski and

Maciej Płaszewski

submission deadline 31 Aug 2025 | Viewed by 88 | Submission Open

Keywords: evidence-based practice; physiotherapy; critique; certainty of evidence; clinical practice guidelines; implementa-tion; clinical settings; clinical practice; clinical processing

(This special issue belongs to the Section Clinical Rehabilitation)

Diagnosis, Emerging Therapies, and Biomarkers in Ovarian Cancer: Shaping the Future of Clinical Practice

edited by Daniela Luvero

submission deadline 31 Aug 2025 | Viewed by 84 | Submission Open

Keywords: ovarian cancer; PARPi; targeted therapies; BRCA mutation; HRD status; precision oncology

(This special issue belongs to the Section Obstetrics & Gynecology)

Adverse Pregnancy Outcomes: Current Status, Challenges and Future Directions

edited by

Demetra Socolov

, Iuliana Ceausu and

Elena Bernad

submission deadline 10 Sep 2025 | 10 articles | Viewed by 11253 | Submission Open

Keywords: great obstetrical syndromes; adverse pregnancy outcomes; screening; prediction; prophylaxis; diagnosis; long-term follow-up; perinatal management; intrapartum management

(This special issue belongs to the Section Obstetrics & Gynecology)

The Role of Scleral Lenses in the Management of Eye Disease

edited by Cherie B. Nau

submission deadline 10 Sep 2025 | 1 articles | Viewed by 2167 | Submission Open

Keywords: scleral lenses; corneal irregularity; corneal disease; dry eye disease; irregular astigmatism; keratoconus; meibomian gland dysfunction; midday fogging

(This special issue belongs to the Section Ophthalmology)

Ocular Surface, Retina, and Choroid as Mirrors of Systemic and Genetic Diseases

edited by

Giacomo Visioli

Alisi Ludovico

and

Alessandro Lambiase

submission deadline 10 Sep 2025 | 1 articles | Viewed by 913 | Submission Open

Keywords: ocular surface; retina; choroid; systemic diseases; genetic conditions; biomarkers; diagnostic imaging; neuroretina; infectious diseases

(This special issue belongs to the Section Ophthalmology)

Chronic Coronary Artery Disease: New Treatments and Future Directions

edited by

Ioannis Vogiatzis

submission deadline 10 Sep 2025 | Viewed by 239 | Submission Open

Keywords: risk assessment; coronary atherosclerosis; platelet disorders; lipid reduction; angina; percutaneous coronary intervention (PCI); coronary artery bypass grafting (CABG); patient recovery and rehabilitation; smoking; second-hand smoke and e-cigarettes cessation

(This special issue belongs to the Section Cardiovascular Medicine)

Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders

edited by

Argyro Pachi

Ioannis Ilias

and

Athanassios Tselebis

submission deadline 12 Sep 2025 | 2 articles | Viewed by 3415 | Submission Open

Keywords: sleep; circadian rhythms; insomnia; depression; physical health; mental health; circadian medicine; chronotype; chronotherapy; melatonin

(This special issue belongs to the Section Mental Health)

Current Trends in Vascular and Endovascular Surgery

edited by Karin Pfister and Fiona Rohlffs

submission deadline 15 Sep 2025 | 12 articles | Viewed by 16028 | Submission Open

Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept

(This special issue belongs to the Section Vascular Medicine)

Emerging Technologies for Dental Imaging

edited by

Egon Burian

submission deadline 15 Sep 2025 | 5 articles | Viewed by 7577 | Submission Open

Keywords: dental imaging; dental MRI; caries; periodontitis; orthodontics; oral surgery; craniomaxillofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neuroimaging in 2024 and Beyond

edited by

Alberto Negro

and Lorenzo Ugga

submission deadline 15 Sep 2025 | 5 articles | Viewed by 6210 | Submission Open

Keywords: neuroimaging; neuroradiology; neuro-oncology; brain degenerative disease; magnetic resonance imaging; neurosurgery; neurology

(This special issue belongs to the Section Clinical Neurology)

Antiphospholipid Syndrome: Clinical Advances in Diagnosis and Management

edited by Mattia Galli and

Alessandra Ida Celia

submission deadline 15 Sep 2025 | 4 articles | Viewed by 3091 | Submission Open

Keywords: antiphospholipid syndrome; antiphospholipid antibodies; systemic lupus erythematosus; immunosuppressive therapy; diagnosis; management

(This special issue belongs to the Section Immunology)

Foot and Ankle Surgery: Clinical Challenges and New Insights

edited by

Byung-Ki Cho

submission deadline 15 Sep 2025 | 4 articles | Viewed by 2854 | Submission Open

Keywords: hallux valgus; minimally invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

New Trends in the Management of Periodontitis and Peri-Implantitis

edited by

João Botelho

submission deadline 15 Sep 2025 | 1 articles | Viewed by 1459 | Submission Open

Keywords: periodontitis; periodontal disease; peri-implantitis; regenerative therapies; diagnostic markers; biomaterials; personalized medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Issues in Gynecologic Cancer Prevention and Screening

edited by

Taek Sang Lee

submission deadline 15 Sep 2025 | 1 articles | Viewed by 817 | Submission Open

Keywords: gynecologic cancer; prevention; screening

(This special issue belongs to the Section Oncology)

Recent Advances in the Management of Fractures

edited by Giulio Maccauro and

Raffaele Vitiello

submission deadline 15 Sep 2025 | 1 articles | Viewed by 348 | Submission Open

Keywords: trauma; fractures; prosthesis; megaprosthesis; modular prosthesis; plate; nail; combo; screw; rehabilitation; radiology

(This special issue belongs to the Section Orthopedics)

Current Challenges and Future Directions in Lung Resections in Thoracic Surgery

edited by Vasileios K. Kouritas and Emmanuel Michael Kefaloyannis

submission deadline 15 Sep 2025 | 1 articles | Viewed by 235 | Submission Open

Keywords: robotic-assisted thoracic surgery (RATS); robotic; sublobar; 3D; emphysema; endobronchial valves; lung volume reduction surgery (LVRS); high-risk; AI; research; lung; screening; lung cancer

(This special issue belongs to the Section General Surgery)

Paradigm Changes in Cardiac Surgery and Interventional Cardiology

edited by

Miklos Bitay

submission deadline 15 Sep 2025 | Viewed by 76 | Submission Open

Keywords: cardiac surgery; trans-catheter interventions; ischaemic heart disease; structural heart disease; electrophysiological interventions; state-of-the-art techniques; golden standards; therapeutic guidelines

(This special issue belongs to the Section Cardiology)

Advanced Hysteroscopic Technology for Gynecological Disease

edited by

Guglielmo Stabile

Luigi Nappi

and

Felice Sorrentino

submission deadline 17 Sep 2025 | Viewed by 102 | Submission Open

Keywords: hysteroscopy; new technology; therapy; mini-invasive approach; laser; diagnosis; outcomes

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Breast Reconstruction: New Technologies Improving Clinical Outcomes

edited by Luigi Antonio Valdatta

submission deadline 18 Sep 2025 | 1 articles | Viewed by 328 | Submission Open

Keywords: breast reconstruction; acellular dermal matrix (ADM); artificial intelligence in surgery; advanced prostheses; breast malformation correction; 3D printing in reconstruction; robotic-assisted breast surgery; regenerative surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Kidney Transplantation

edited by Florin Ioan Elec and

Oana Antal

submission deadline 19 Sep 2025 | 1 articles | Viewed by 435 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Dual-Energy and Spectral CT in Clinical Practice: 2nd Edition

edited by

Giovanni Foti

submission deadline 19 Sep 2025 | Viewed by 131 | Submission Open

Keywords: dual-energy CT; spectral CT; photon counting CT; oncology; bone marrow edema; prosthesis; liver; pancreas; lung; kidney; adrenal; brain; abdomen; cardiac; coronary arteries; arthritis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Spine Surgery and Rehabilitation: Current Advances and Future Options

edited by Delia Cannizzaro

submission deadline 20 Sep 2025 | 10 articles | Viewed by 19440 | Submission Open

Keywords: spinal cord injury; neuronal plasticity; spinal surgery; spinal deformities; spinal tumors; motor rehabilitation; physical therapy modalities

(This special issue belongs to the Section Orthopedics)

Advances in Clinical Rheumatology

edited by

Jacopo Ciaffi

submission deadline 20 Sep 2025 | 11 articles | Viewed by 13990 | Submission Open

Keywords: rheumatoid arthritis; spondyloarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology)

Current Progress and Future Directions of Spine Surgery

edited by

Dong-Gune Chang

and Sam Yeol Chang

submission deadline 20 Sep 2025 | 12 articles | Viewed by 11787 | Submission Open

Keywords: minimally invasive surgery; navigation-assisted spine surgery; robotic-assisted spine surgery; deformity correction; spinal fusion; osteobiologic; surface technology; expandable cage; artificial intelligence; machine learning algorithms

(This special issue belongs to the Section Orthopedics)

Musculoskeletal Infections: Clinical Diagnosis and Treatment

edited by

Kalliopi Alpantaki

and

Apostolos Karantanas

submission deadline 20 Sep 2025 | 6 articles | Viewed by 10206 | Submission Open

Keywords: computed tomography; magnetic resonance; musculoskeletal infections; septic arthritis; osteomyelitis; fungal infections; mycobacterium infections; prosthetic joint infections; postoperative infections; surgical treatment; VAC; hyperbaric oxygen

(This special issue belongs to the Section Orthopedics)

Clinical Innovations in Digestive Disease Diagnosis and Treatment

edited by

Stefano Rausei

and Angelo Benevento

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7751 | Submission Open

Keywords: gastroenterology; digestive diseases; gastrointestinal endoscopy; upper GI surgery; colorectal surgery; hepatobiliary surgery; anastomotic leakage; gastrointestinal surgical oncology; inflammatory bowel disease; precision medicine in gastroenterology; minimally invasive gastrointestinal procedures; SIPAD congress contributions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Reconstructive Urology and Prosthetic Surgery

edited by Francisco E. Martins, Maurice Garcia and Jay Simhan

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4875 | Submission Open

Keywords: male and female urogenital reconstruction; urologic trauma; urologic prosthetics; erectile dysfunction; urinary incontinence; artificial urinary sphincter; gender-affirming surgery; transgender; phalloplasty; vaginoplasty

(This special issue belongs to the Section Nephrology & Urology)

New Insights into Glaucoma

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 20 Sep 2025 | 6 articles | Viewed by 4671 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Obsessive Compulsive Disorder: Clinical Advances and Future Perspectives

edited by Andrea Fagiolini

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4266 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

New Perspectives on the Diagnosis and Treatment of Liver Cirrhosis

edited by Elba Llop

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4233 | Submission Open

Keywords: liver cirrhosis; portal hypertension; non-invasive diagnosis; elastography; gastro-esophagueal varices

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Catheter Ablation of Atrial Fibrillation: Advances and Challenges

edited by Nicholas Yick Loong Tan and Christopher V. DeSimone

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3655 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulmonary vein isolation; cardiac electrophysiology; cardiac resynchronization therapy; pulsed field ablation; hybrid ablation; non-pulmonary vein triggers

(This special issue belongs to the Section Cardiology)

Clinical Management of Prosthetic Joint Infection (PJI)

edited by Daniel Pérez-Prieto

submission deadline 20 Sep 2025 | 5 articles | Viewed by 3435 | Submission Open

Keywords: prosthetic joint infection; debridement; biofilm; wound healing; multidisciplinary team; osteomyelitis

(This special issue belongs to the Section Orthopedics)

Musculoskeletal Rehabilitation and Regenerative Medicine: Current Challenges and New Perspectives

edited by

Raffaele Vitiello

and Gianpaolo P. Ronconi

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3253 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; enhanced recovery after surgery; chronic pain; disability; regenerative medicine; personalized medicine

(This special issue belongs to the Section Clinical Rehabilitation)

Perioperative Anesthesia: State of the Art and the Perspectives

edited by

Benedikt Preckel

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3225 | Submission Open

Keywords: preoperative risk evaluation; prehabilitation; hemodynamic monitoring; post-surgical monitoring; patient deterioration; human factors; non-technical skills; cognitive aids; anesthetic drugs; regional anesthesia; healthcare worker wellness

(This special issue belongs to the Section Anesthesiology)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3007 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Personalized Treatments for Glaucoma Patients

edited by Gloria Roberti

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2688 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); optic nerve damage; visual field loss; ophthalmoscopy; angle closure glaucoma; open-angle glaucoma; primary glaucoma; secondary glaucoma; normal-tension glaucoma; pigmentary glaucoma

(This special issue belongs to the Section Ophthalmology)

Risk Prediction for Gynecological Cancer

edited by

Federico Ferrari

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2608 | Submission Open

Keywords: cervical cancer; endometrial cancer; tubo-ovarian cancer; diagnosis; treatment; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Stigma and Discrimination in Pediatric Mental Health

edited by

Clara González-Sanguino

and

Jairo Rodríguez-Medina

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2535 | Submission Open

Keywords: stigma; discrimination; childhood; mental health; clinical psychology

(This special issue belongs to the Section Mental Health)

Advances in Scoliosis, Spinal Deformity, and Other Spinal Disorders: 2nd Edition

edited by

Zach Pennington

Daniel M. Sciubba

and

Benjamin D. Elder

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2143 | Submission Open

Keywords: adult spinal deformity; scoliosis; spinal biomechanics; predictive calculators; bone health optimization; minimally invasive spine surgery; mechanical complication prevention; frailty

(This special issue belongs to the Section Orthopedics)

Diabetic Nephropathy: Current Standards and Future Directions

edited by

Alaa S. Awad

Emaad M. Abdel-Rahman

and Charles W. Heilig

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1627 | Submission Open

Keywords: diabetic nephropathy: standard of care; diabetic nephropathy: future directions; SGLT2 in diabetic nephropathy; markers for diabetic nephropathy; diabetic nephropathy in the elderly; diabetic nephropathy in renal transplant patients; finerenone in diabetic nephropathy

(This special issue belongs to the Section Nephrology & Urology)

Corneal Diseases and Corneal Transplantation: Current Updates and Perspectives

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1203 | Submission Open

Keywords: corneal diseases; corneal transplantation; imaging techniques; pharmacological in-terventions; surgical interventions; tissue engineering

(This special issue belongs to the Section Ophthalmology)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 20 Sep 2025 | 1 articles | Viewed by 985 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Clinical Updates and Perspectives on Subarachnoid Hemorrhage

edited by

Fusao Ikawa

submission deadline 20 Sep 2025 | 2 articles | Viewed by 746 | Submission Open

Keywords: subarachnoid hemorrhage; outcome of subarachnoid hemorrhage; delayed cerebral ischemia; ; ruptured cerebral aneurysm; unruptured cerebral aneurysm; artificial intelligence; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 712 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Displaying special issue 701-750 on page 15 of 27.

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