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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hemophilia: Current Trends and Future Directions

edited by

Jonathan C. Roberts

and

Michael B. Nichol

submission deadline 20 Sep 2025 | 1 articles | Viewed by 594 | Submission Open

Keywords: hemophilia; prophylaxis; gene therapy; burden of illness; quality of life; patient reported outcomes; hemarthrosis; women and hemophilia

(This special issue belongs to the Section Hematology)

Foot Disorders: Multidisciplinary Perspectives on Prevention and Treatment

edited by Aksone L. Nouvong and Neil M. Paige

submission deadline 20 Sep 2025 | 1 articles | Viewed by 561 | Submission Open

Keywords: foot deformities; minimally invasive surgery; foot/ankle joint arthroscopy; nail pathology; trauma; neuropathy; Charcot arthropathy; melanoma; tendon injury; fractures; peripheral vascular disease; diabetic foot infections; diabetic foot ulcer; lower limb amputation

(This special issue belongs to the Section Orthopedics)

The Current State of Robotic Surgery in Urology

edited by

Luca Di Gianfrancesco

submission deadline 20 Sep 2025 | 1 articles | Viewed by 528 | Submission Open

Keywords: robotic surgery; urology; surgical technique; multi-port; single port; major urological surgery; reconstructive surgery; robot-assisted radical cystectomy; patients’ selection

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Diagnosis and Treatment of Acute Kidney Injury

edited by Gianpaolo Reboldi and

Mario Bonomini

submission deadline 20 Sep 2025 | 1 articles | Viewed by 471 | Submission Open

Keywords: acute kidney injury; diagnosis; biomarkers; early detection; prognosis; renal replacement therapy

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Management of Intracranial Aneurysms

edited by Robert H. Rosenwasser, Nikolaos Mouchtouris and Elias Atallah

submission deadline 20 Sep 2025 | Viewed by 282 | Submission Open

Keywords: cerebral aneurysm; endovascular; open vascular; flow diversion; cerebral bypass; stent-assisted coiling

(This special issue belongs to the Section Clinical Neurology)

Pancreatic Surgery: Clinical Practices and Challenges

edited by Guido Alsfasser and

Roberto Salvia

submission deadline 20 Sep 2025 | Viewed by 218 | Submission Open

Keywords: prognostic variables; surgical technique; outcome; timing of surgery; perioperative strategies; pancreatic cancer; pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries

edited by Nili Steinberg

submission deadline 20 Sep 2025 | Viewed by 129 | Submission Open

Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent

(This special issue belongs to the Section Sports Medicine)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2025 | Viewed by 128 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Laparoscopic Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Sep 2025 | Viewed by 121 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2025 | Viewed by 119 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

New Insights into the Management of Psoriasis and Cardiovascular Disease

edited by Amit Kumar Dey

submission deadline 20 Sep 2025 | Viewed by 68 | Submission Open

Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; chronic inflammation; cardiometabolic disease

(This special issue belongs to the Section Dermatology)

Aortic Aneurysms: Recent Advances in Diagnosis and Treatment

edited by Marco Virgilio Usai, Giuseppe Asciutto and Michele Piazza

submission deadline 23 Sep 2025 | 2 articles | Viewed by 1893 | Submission Open

Keywords: aortic aneurysms; abdominal aortic; thoraco-abdominal aortic aneurysms (TAAAs); complex aortic anatomies; endovascular abdominal aortic aneurysm repair (EVAR); endovascular thoracic aortic aneurysm repair (TEVAR); endovascular treatment

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Minimally Invasive Vascular Surgery

edited by Ben Li and

Mohammad Qadura

submission deadline 23 Sep 2025 | 1 articles | Viewed by 502 | Submission Open

Keywords: minimally invasive vascular surgery; endovascular surgery; angioplasty; stenting; atherectomy; robotics; peripheral vascular intervention; carotid stenting; transcarotid artery revascularization; endovascular aneurysm repair

(This special issue belongs to the Section Vascular Medicine)

Hypertension: Clinical Treatment and Management

edited by José L. Flores-Guerrero

submission deadline 24 Sep 2025 | Viewed by 96 | Submission Open

Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies

(This special issue belongs to the Section Epidemiology & Public Health)

Endocrine Tumors: Diagnosis, Treatment, and Management

edited by

Jules T. Zhang-Yin

Francesco Dondi

and Emmanouil Panagiotidis

submission deadline 25 Sep 2025 | 7 articles | Viewed by 8064 | Submission Open

Keywords: neuroendocrine tumors; thyroid cancer; adrenal gland tumors; pituitary adenomas; parathyroid tumors; pancreatic neuroendocrine tumors; surgical management; radiotherapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Inborn Errors of Immunity: Advances in Diagnosis and Treatment

edited by Jolanta Bernatoniene

submission deadline 25 Sep 2025 | 2 articles | Viewed by 6678 | Submission Open

Keywords: inborn errors of immunity (IEI); primary immunodeficiencies (PID); chronic granulomatous disease; PIK3CD mutations; immunology; autoimmunity

(This special issue belongs to the Section Immunology)

Acute Respiratory Distress Syndrome (ARDS): Causes, Management, and Treatment

edited by Gabriele Sales and Francesca Collino

submission deadline 25 Sep 2025 | 3 articles | Viewed by 6257 | Submission Open

Keywords: acute respiratory distress syndrome; mechanical ventilation; lung-protective ventilation; extracorporeal membrane oxygenation; ventilator-induced lung injury; hypoxemia; rescue therapies; pronation; lung physiology; clinical outcome

(This special issue belongs to the Section Respiratory Medicine)

Ultrasound Diagnosis of Obstetrics and Gynecologic Diseases

edited by

Florian Recker

submission deadline 25 Sep 2025 | 4 articles | Viewed by 5811 | Submission Open

Keywords: obstetric ultrasound; gynecologic sonography; 3D/4D ultrasound imaging; fetal imaging techniques; prenatal screening; gynecologic oncology; ultrasound elastography; contrast-enhanced ultrasound; ultrasound in fertility; ultrasound training and education; clinical ultrasound standardization; diagnostic imaging in obstetrics and gynecology; personalized medicine in ultrasound diagnosis; ethical considerations in obstetric ultrasound; technological advancements in ultrasound imaging

(This special issue belongs to the Section Obstetrics & Gynecology)

Pancreatic Cancer: Current and Emerging Treatment Options

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 5404 | Submission Open

Keywords: pancreatic cancer; treatment options; emerging therapies; precision medicine; immunotherapy; targeted therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Perspectives in Stroke Rehabilitation

edited by Krystyna Jaracz,

Karolina Filipska-Blejder

and Robert Ślusarz

submission deadline 25 Sep 2025 | 6 articles | Viewed by 5111 | Submission Open

Keywords: stroke; clinical perspectives; therapy; functional outcome predictors; rehabilitation; quality of life

(This special issue belongs to the Section Clinical Rehabilitation)

Sleep in Neurology—Sleep Disorders and Dysfunction of the Nervous System

edited by

Mariusz Siemiński

submission deadline 25 Sep 2025 | 4 articles | Viewed by 4609 | Submission Open

Keywords: sleep; neurology; insomnia; restless leg syndrome; REM sleep behavior disorder; parasomnia; somnambulism; neurodegenerative disorders; brain injury; sleep-related movement disorders

(This special issue belongs to the Section Clinical Neurology)

Rehabilitation and Management of Stroke

edited by Thomas Platz

submission deadline 25 Sep 2025 | 3 articles | Viewed by 4038 | Submission Open

Keywords: stroke; rehabilitation; evidence; implementation; neurology; neurorehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Innovations and Advances in Breast Cancer Research and Treatment

edited by

Palma Fedele

submission deadline 25 Sep 2025 | 3 articles | Viewed by 3888 | Submission Open

Keywords: breast cancer; early detection; genomics; personalized medicine; targeted therapies; survivorship; quality of life; artificial intelligence; machine learning; immunotherapy

(This special issue belongs to the Section Oncology)

Surgical Treatment for Lung Cancer

edited by

Piotr Gabryel

, Cezary Piwkowski and Marek Ochman

submission deadline 25 Sep 2025 | 4 articles | Viewed by 3804 | Submission Open

Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy

(This special issue belongs to the Section Respiratory Medicine)

Clinical Perspectives on Foot and Ankle Surgery

edited by Kenichiro Nakajima

submission deadline 25 Sep 2025 | 3 articles | Viewed by 3221 | Submission Open

Keywords: foot and ankle; minimally invasive surgery; surgical techniques; new technologies; diagnosis; clinical assessment

(This special issue belongs to the Section Orthopedics)

Interaction Between Systemic Diseases and Oral Diseases

edited by

Henk S. Brand

submission deadline 25 Sep 2025 | 3 articles | Viewed by 3183 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Treatment of Bladder Cancer: From Past to Future

edited by Jørgen Bjerggaard Jensen

submission deadline 25 Sep 2025 | 2 articles | Viewed by 3017 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; nonmuscle-invasive bladder cancer; muscle-invasive bladder cancer

(This special issue belongs to the Section Oncology)

Clinical Advances in Valvular Heart Diseases

edited by

Mohammad Kassar

submission deadline 25 Sep 2025 | 3 articles | Viewed by 2853 | Submission Open

Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis

(This special issue belongs to the Section Cardiology)

Clinical Updates on Diabetes Mellitus and Carbohydrate Metabolism-Related Diseases

edited by

Tatsuya Fukuda

submission deadline 25 Sep 2025 | 2 articles | Viewed by 2683 | Submission Open

Keywords: diabetes; diabetic complications; cardiovascular disease; carbohydrate; endocrinology treatment strategies

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Advances in Endometriosis: An Update

edited by

Mislav Mikuš

, Mario Ćorić and

Antonio Simone Laganà

submission deadline 25 Sep 2025 | 4 articles | Viewed by 2247 | Submission Open

Keywords: endometriosis; gynecological diseases; adenomyosis; classification; diagnosis; treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Strategies for Preventing and Managing Postoperative Complications in Minimally Invasive Surgery

edited by Shingo Tsujinaka

submission deadline 25 Sep 2025 | 2 articles | Viewed by 2134 | Submission Open

Keywords: minimally invasive surgery; postoperative complications; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes

(This special issue belongs to the Section General Surgery)

Moving Forward to New Trends in Pulmonary Diseases

edited by

Ramona Cioboata

and

Costin Teodor Streba

submission deadline 25 Sep 2025 | 3 articles | Viewed by 2054 | Submission Open

Keywords: pulmonary tuberculosis; chronic obstructive airway diseases; bronchiectasis; COVID-19; sleep apnea; ultrasound; lung cancer; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Infective Endocarditis: What Is New in the Clinical Research: 2nd Edition

edited by

Petros Ioannou

submission deadline 25 Sep 2025 | 1 articles | Viewed by 2051 | Submission Open

Keywords: infective endocarditis; vegetation; native valve; prosthetic valve; aortic valve; mitral valve; cardiac device; bloodstream infection; bacteremia

(This special issue belongs to the Section Cardiovascular Medicine)

Dentistry and Oral Surgery: Current Status and Future Prospects

edited by

Dragana Gabrić

Ivona Bago

and

Marko Vuletić

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1337 | Submission Open

Keywords: dentistry; oral surgery; dental implantology; prosthodontics; restorative dentistry; periodontology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Gastric Cancer and Peritoneal Diseases

edited by Shin Saito

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1231 | Submission Open

Keywords: gastric cancer; peritoneal disease; conversion surgery; intraperitoneal chemotherapy; potential biomarker

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Biomarkers and Diagnostics in Neurological Diseases

edited by Maria Ioanna Stefanou

submission deadline 25 Sep 2025 | 2 articles | Viewed by 899 | Submission Open

Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation

edited by Young-Jin Seo

submission deadline 25 Sep 2025 | 1 articles | Viewed by 613 | Submission Open

Keywords: anterior cruciate ligament (ACL); reconstruction; lateral extra-articular procedures; all-inside technique; internal bracing; slope reducing osteotomy; biologic augmentation; rehabilitation

(This special issue belongs to the Section Orthopedics)

Intracranial Aneurysms: Diagnostics and Current Treatment

edited by Vincenzo Antonelli and

Roberto Colasanti

submission deadline 25 Sep 2025 | 1 articles | Viewed by 597 | Submission Open

Keywords: neurovascular diseases; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms; subarachnoid hemorrhage; neurorehabiltation

(This special issue belongs to the Section Clinical Neurology)

Airway Management: From Basic Techniques to Innovative Technologies

edited by Kunal Karamchandani and Sheila Nainan Myatra

submission deadline 25 Sep 2025 | 1 articles | Viewed by 556 | Submission Open

Keywords: airway management; physiologically difficult airway; videolaryngoscopy; esophageal intubation; artificial intelligence

(This special issue belongs to the Section Intensive Care)

Diagnosis and Surgical Treatment for Colorectal Cancer

edited by Nidal Issa, Wisam Khoury and Rachel Gingold-Belfer

submission deadline 25 Sep 2025 | 1 articles | Viewed by 547 | Submission Open

Keywords: colorectal cancer; laparoscopy; colonoscopy; colectomy; diagnosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Updates in Imaging of Rheumatologic and Neoplastic Musculoskeletal Diseases

edited by Olympia G. Papakonstantinou

submission deadline 25 Sep 2025 | 1 articles | Viewed by 472 | Submission Open

Keywords: musculoskeletal imaging; radiology; functional imaging; artificial intelligence; advanced MRI techniques; musculoskeletal systems; orthopedics; sport medicine; traumatology; rehabilitation; fracture; muscle; connective tissues; clinical relevance; soft tissues; joints; multidisciplinary management; diagnosis; treatment; management; challenges

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Developments of Oral and Maxillofacial Surgery

edited by

José María Martinez-Gonzalez

and

Natalia Martínez-Rodríguez

submission deadline 25 Sep 2025 | 1 articles | Viewed by 408 | Submission Open

Keywords: oral surgery; maxillofacial surgery; bone resorption; implant surgery; oral rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advanced Approaches in Hip and Knee Arthroplasty

edited by Filippo Randelli and Alberto Fioruzzi

submission deadline 25 Sep 2025 | 1 articles | Viewed by 350 | Submission Open

Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis and Treatment of Hypertrophic Cardiomyopathy

edited by

Milorad Tesic

Vojislav Giga

and

Djordje G. Jakovljević

submission deadline 25 Sep 2025 | Viewed by 309 | Submission Open

Keywords: hypertrophic cardiomyopathy; left ventricular hypertrophy; diagnosis; multimodality imaging; genetics; treatment; risk stratification; outcome; biomarkers

(This special issue belongs to the Section Cardiology)

Ovarian Cancer: Clinical Updates and Advances

edited by

Maciej Stukan

submission deadline 25 Sep 2025 | Viewed by 292 | Submission Open

Keywords: ovarian cancer; prehabilitation; ultrasound; radiologic staging; cytoreductive surgery; targeted treatment; prevention; screening

(This special issue belongs to the Section Obstetrics & Gynecology)

Emerging Trends and Innovations in Restorative Dentistry: Advances in Clinical Practice

edited by

Oana Almasan

submission deadline 25 Sep 2025 | Viewed by 278 | Submission Open

Keywords: restorative dentistry; clinical practice; artificial intelligence; 3D printing; endodontics; prosthodontics; periodontics; dental surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Advances in Interventional Oncology

edited by

Thomas Vogl

submission deadline 25 Sep 2025 | Viewed by 239 | Submission Open

Keywords: interventional oncology/radiology; vascular locoregional therapies; thermal ablation; treatment options; imaging-guided biopsies

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Lung Transplantation: Clinical Advances and Practice Updates

edited by Milton Saute

submission deadline 25 Sep 2025 | Viewed by 202 | Submission Open

Keywords: lung transplantation; respiratory failure; thoracic surgery; cardiothoracic surgery; solid organ transplantation; immunosuppression; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Clinical Perspectives in Cardiac Imaging: How to See the Unseen

edited by

Adriana D'Antonio

and Wanda Acampa

submission deadline 25 Sep 2025 | Viewed by 197 | Submission Open

Keywords: cardiac imaging; MPI; PET; SPECT; CCTA; MR; CAD; heart failure; cardiac sarcoidosis; cardiac amyloidosis; valvular disease; artificial intelligence

(This special issue belongs to the Section Cardiology)

Recent Advances in Prenatal Diagnosis and Maternal Fetal Medicine

edited by

Anca Angela Simionescu

and

Ştefania Tudorache

submission deadline 25 Sep 2025 | Viewed by 164 | Submission Open

Keywords: prenatal; obstetrics; fetal abnormalities; intrauterine treatments; genetic disorders; pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

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