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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Management and Challenges of Sepsis and Septic Shock

edited by

Matteo Guarino

and

Michele Domenico Spampinato

submission deadline 15 Sep 2026 | 1 articles | Viewed by 337 | Submission Open

Keywords: sepsis; septic shock; hemodynamic management; biomarkers; cardiovascular dysfunction; point-of-care ultrasound; precision medicine; emergency medicine; critical care

(This special issue belongs to the Section Intensive Care)

Clinical Advances in Endodontics

edited by

Vincenzo Tosco

submission deadline 15 Sep 2026 | Viewed by 235 | Submission Open

Keywords: endodontics; vital pulp therapy; minimally invasive endodontics; clinical endodontic techniques; bioactive sealers

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

State of the Art of Lung Surgery: Modern Horizons in Lung Cancer Treatment

edited by

Alessio Mariolo

and Edouard Sage

submission deadline 15 Sep 2026 | Viewed by 229 | Submission Open

Keywords: lung-cancer-surgery; thoracic oncology; RATS; VATS; induction therapy; neoadjuvant-immunotherapy; non-intubated thoracic surgery; NITS; segmentectomy; lung-sparing surgery; 3D-reconstruction

(This special issue belongs to the Section General Surgery)

Advances in Pulmonary Arterial Hypertension: Emerging Therapies and Clinical Outcomes

edited by Namita Sood

submission deadline 15 Sep 2026 | Viewed by 221 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); PAH therapy; emerging treatments; sotatercept; inhaled therapy; targeted pharmacotherapy; combination therapy; therapeutic efficacy; pulmonary vascular imaging

(This special issue belongs to the Section Respiratory Medicine)

Sports Injuries: Emerging Trends in Risk Mitigation, Management and Recovery

edited by

Luis Suárez-Arrones

and Jose Asian-Clemente

submission deadline 15 Sep 2026 | 1 articles | Viewed by 211 | Submission Open

Keywords: injury prevention; rehabilitation; muscle; return-to-sport; surgery; therapy; testing; regenerative medicine; ultrasound; MRI; sports medicine

(This special issue belongs to the Section Sports Medicine)

Recent Clinical Updates on Vascular and Endovascular Surgery

edited by

Mª Lourdes Del Río-Solá

and

Sergi Bellmunt-Montoya

submission deadline 15 Sep 2026 | Viewed by 206 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic disease; abdominal aortic aneurysm; peripheral arterial disease; chronic venous disease; endovascular repair; open vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Advances in Pancreatic Cancer: Diagnosis and Therapy

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 15 Sep 2026 | Viewed by 190 | Submission Open

Keywords: pancreatic cancer diagnosis; endoscopic ultrasound; neoadjuvant chemotherapy; surgical resection; targeted therapy; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cancers: Clinical Radiation Therapy

edited by Julianne M. Pollard-Larkin

submission deadline 15 Sep 2026 | Viewed by 181 | Submission Open

Keywords: reirradiation; tissue tolerance; image registration; treatment planning; dose accumulation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Innovations and Advancements in Spine Surgery

edited by Mitchell K. Ng

submission deadline 15 Sep 2026 | Viewed by 177 | Submission Open

Keywords: spine surgery; minimally invasive spine surgery; robotic-assisted spine surgery; spinal navigation; endoscopic spine surgery; spinal implant; biologics and regenerative therapies; perioperative optimization; patient-reported outcomes; value-based spine care; surgical innovation

(This special issue belongs to the Section Orthopedics)

New Insights into Acute Care and Emergency Surgery: 2nd Edition

edited by Jacob Chen and Avi Benov

submission deadline 15 Sep 2026 | Viewed by 162 | Submission Open

Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU

(This special issue belongs to the Section General Surgery)

Innovations in Advanced Heart Failure Detection and Management

edited by Vinh Q. Chau and Nikhil Narang

submission deadline 15 Sep 2026 | Viewed by 138 | Submission Open

Keywords: advanced heart failure; systolic heart failure; mechanical circulatory support; left ventricular assist device; heart transplantation outcomes

(This special issue belongs to the Section Cardiology)

Advances in Endoscopic Techniques for Gastrointestinal Diseases

edited by Alberto Tringali

submission deadline 15 Sep 2026 | Viewed by 119 | Submission Open

Keywords: hepatobiliary disease; pancreatic disease; ERCP; interventional EUS; cholangiopancreatoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiac Imaging in the Clinical Management of Heart Failure

edited by Maria Concetta Pastore

submission deadline 15 Sep 2026 | Viewed by 113 | Submission Open

Keywords: heart failure; cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Application of Physiotherapy in Clinical Rehabilitation

edited by

Kyeongbong Lee

submission deadline 17 Sep 2026 | Viewed by 227 | Submission Open

Keywords: therapeutic exercise; neurological rehabilitation; musculoskeletal physiotherapy; cardiopulmonary rehabilitation; intensive care unit (ICU) rehabilitation; gait and balance; pediatric and geriatric physical therapy; sports physical therapy; rehabilitation technology

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 18 Sep 2026 | 4 articles | Viewed by 6785 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives in Pediatric Surgery: From Neonatal Procedures to Adolescent Care

edited by

Mirko Bertozzi

and

Giovanna Riccipetitoni

submission deadline 18 Sep 2026 | 1 articles | Viewed by 540 | Submission Open

Keywords: mini invasive surgery; transitional care of rare diseases; newborn surgery; long-term follow up; congenital malformations

(This special issue belongs to the Section Clinical Pediatrics)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2026 | 9 articles | Viewed by 26167 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2026 | 12 articles | Viewed by 19884 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Sep 2026 | 3 articles | Viewed by 15495 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Sep 2026 | 4 articles | Viewed by 13921 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Sep 2026 | 5 articles | Viewed by 11239 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Sep 2026 | 4 articles | Viewed by 10194 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Sep 2026 | 6 articles | Viewed by 8826 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2026 | 6 articles | Viewed by 7385 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Sep 2026 | 5 articles | Viewed by 6607 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Current Challenges and New Perspectives in Liver Transplantation

edited by

Anna Mrzljak

and

Quirino Lai

submission deadline 20 Sep 2026 | 9 articles | Viewed by 6377 | Submission Open

Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Sep 2026 | 5 articles | Viewed by 5098 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Cognitive Impairment, Dementia and Depression in Older Adults

edited by Seong Jae Kim and Ilhan Choo

submission deadline 20 Sep 2026 | 3 articles | Viewed by 4890 | Submission Open

Keywords: cognitive impairment; dementia; depression; Parkinson’ s disease; artificial intelligence (AI); predictive modeling

(This special issue belongs to the Section Geriatric Medicine)

New Advances in Systemic Lupus Erythematosus (SLE)

edited by

Chang-Hee Suh

submission deadline 20 Sep 2026 | 2 articles | Viewed by 4564 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life

(This special issue belongs to the Section Immunology & Rheumatology)

Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies

edited by Raanan Meyer

submission deadline 20 Sep 2026 | 3 articles | Viewed by 4291 | Submission Open

Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Sep 2026 | 4 articles | Viewed by 3761 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3137 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

Ana Filipa Beato

and

Stephanie Alves

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2515 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Minimally Invasive and Endoscopic Neurosurgery

edited by

Nikolaos Gkantsinikoudis

, Vassilios Tsitouras and Stylianos Kapetanakis

submission deadline 20 Sep 2026 | 1 articles | Viewed by 2406 | Submission Open

Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy

(This special issue belongs to the Section Clinical Neurology)

Minimally Invasive Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Sep 2026 | 2 articles | Viewed by 2282 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

Innovations in Emergency and Critical Care Medicine

edited by Yoshiaki Iwashita

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2128 | Submission Open

Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography

(This special issue belongs to the Section Intensive Care)

Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications

edited by

Thenral Socrates

and

Federica Piani

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2068 | Submission Open

Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

Harald Krentel

and Maya Sophie de Wilde

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2010 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’ s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

Personalized Treatments for Patients with Acute Lung Injury

edited by

Gary F. Nieman

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1985 | Submission Open

Keywords: personalized; acute lung injury; acute respiratory distress syndrome (ARDS); ventilator-induced lung injury (VILI); pharmacotherapy; fluid resuscitation; phenotypes; mesenchymal stem cells; nano-systems; exosomes; biomarkers; computational models

(This special issue belongs to the Section Respiratory Medicine)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1740 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Advancements and Challenges in Retina Surgery: Second Edition

edited by Joaquín Marticorena and

Javier Zarranz-Ventura

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1697 | Submission Open

Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Emerging Radiotherapy Technologies and Trends

edited by

Michele Fiore

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1645 | Submission Open

Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy

(This special issue belongs to the Section Oncology)

Residual Risk in High-Risk Patients Undergoing Percutaneous Coronary Intervention

edited by

Giampiero Vizzari

and

Antonio Micari

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1595 | Submission Open

Keywords: cardiology; precision medicine; residual risk; acute coronary syndrome; percutaneous coronary intervention; PCI

(This special issue belongs to the Section Cardiology)

Advances in Antithrombotic Therapy in Cardiovascular Medicine

edited by Daniele Giacoppo and Antonio Greco

submission deadline 20 Sep 2026 | 4 articles | Viewed by 1589 | Submission Open

Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis

(This special issue belongs to the Section Cardiovascular Medicine)

Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices

edited by

Jae-Yeol Lee

submission deadline 20 Sep 2026 | 3 articles | Viewed by 1515 | Submission Open

Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management in Chronic Pain: Innovations, Integration, and Interventions

edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1505 | Submission Open

Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Autism Management

edited by

Justyna Podgórska-Bednarz

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1505 | Submission Open

Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization

(This special issue belongs to the Section Mental Health)

Up-to-Date Research on Nerve Ultrasound

edited by

Hubertus Axer

and Eman A. Tawfik

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1501 | Submission Open

Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines

(This special issue belongs to the Section Clinical Neurology)

Current Emerging Treatment Options in Atrial Fibrillation

edited by Hoang Nhat Pham and Amitoj Singh

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1479 | Submission Open

Keywords: atrial fibrillation; AF ablation; lifestyle intervention; rhythm control; pulsed field ablation; antiarrhythmic drugs; direct oral anticoagulants

(This special issue belongs to the Section Cardiology)

Neurological Injury After Cardiac Arrest: Mechanisms, Prognostication, and Emerging Therapies

edited by

Marco Mion

and Nikos Gorgoraptis

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1459 | Submission Open

Keywords: cardiac arrest; hypoxic– ischaemic brain injury; neuroprognostication; neuroprotection; biomarkers; targeted tem-perature management; multimodal monitoring; neurorehabilitation

(This special issue belongs to the Section Emergency Medicine)

Displaying special issue 751-800 on page 16 of 31.

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