Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 26
Special Issue Editor
Interests: structural heart interventions; transcatheter aortic valve implantation (TAVI); transcatheter edge-to-edge repair (TEER); paravalvular leak closure procedure (PVLc); coronary thrombosis; acute coronary syndromes risk stratification
Special Issue Information
Dear Colleagues,
Transcatheter aortic valve implantation (TAVI) is considered the default intervention for patients with severe symptomatic aortic stenosis in elderly populations or when surgery is not feasible, high risk, or prohibitive. Due to the rapid post-procedure recovery rates coupled with emerging medium- to long-term data, there has been a growing interest in expanding TAVI to low-risk populations. Moreover, TAVI using supra-annular valves may be better than surgery in patients with small aortic annulus at risk of prosthesis–patient mismatch. However, specific patient and anatomical characteristics limit the expansion of TAVI.
TAVI can be challenging in patients with bicuspid aortic valves and complex aortic anatomy, potentially leading to complications like annulus rupture and coronary artery occlusion. Growing operator expertise and newer TAVI valve iterations may mitigate those risks.
The direction of aortic valve surgery is undoubtedly moving towards the keyhole approach with emerging techniques, such as leaflet modification and better algorithms for lifetime management with redo TAV in TAV.
This Special Issue aims to focus on the current treatments and future considerations of TAVI. To this end, state-of-the-art reviews and original research articles focused on contemporary TAVI procedure planning and lifetime management will be warmly welcomed.
Dr. Mohamed Farag
Guest Editor
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Keywords
- transcatheter aortic valve implantation
- TAVI
- bicuspid aortic valve
- small annulus
- prosthesis–patient mismatch
- coronary reaccess
- valve-in-valve TAVI
- leaflet modification
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