You are currently viewing a new version of our website. To view the old version click .

Journal of Clinical Medicine, Volume 14, Issue 16

August-2 2025 - 313 articles

Cover Story: This review compiles evidence on autoantibodies in systemic lupus erythematosus, examining their diagnostic value, phenotypic links, and therapeutic significance. We assess the strength of the connections between specific antibodies and organ involvement, highlighting anti-double-stranded DNA and anti-C1q for monitoring lupus nephritis, the limited specificity of anti-ribosomal P in neuropsychiatric disease, and the roles of anti-Ro/La and antinucleosome antibodies. We combine serology with treat-to-target strategies and explore how emerging targeted therapies intersect with serological profiles, offering an evidence-based roadmap for biomarker-driven care and clinical trials. Finally, we highlight omics-derived biomarkers that complement traditional autoantibodies and enable more precise, phenotype-based treatment. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (313)

  • Article
  • Open Access
776 Views
15 Pages

Structural and Functional Assessment of the Macular Inner Retinal Layers in Multiple Sclerosis Eyes Without History of Optic Neuropathy

  • Lucilla Barbano,
  • Lucia Ziccardi,
  • Carmen Dell’Aquila,
  • Mattia D’Andrea,
  • Carolina Gabri Nicoletti,
  • Doriana Landi,
  • Giorgia Mataluni,
  • Antonio Di Renzo,
  • Fabio Buttari and
  • Roberto dell’Omo
  • + 3 authors

21 August 2025

Background: Considering the lack of studies regarding the localized evaluation of the macular inner retina in multiple sclerosis patients without optic neuritis (MSnoON eyes), we investigated the structure and function of retinal ganglion cells (RGCs...

  • Article
  • Open Access
814 Views
11 Pages

Cervical Regeneration Following Monopolar Electrosurgical Conization: A Prospective Evaluation of Volume, Length, and Transformation Zone Reformation

  • Şule Gül Aydın,
  • Sevda Baş,
  • Fatma Özmen,
  • Şeyma Yaşar,
  • Zeynel Abidin Taş,
  • Ahmet Zeki Nessar,
  • Sevtap Seyfettinoğlu and
  • Mehmet Ali Narin

21 August 2025

Background: The aim of this study was to evaluate the cervical regeneration process following monopolar electrosurgical conization (MESC), using a multimodal approach including ultrasonographic, cytologic, colposcopic, and histologic assessments, and...

  • Article
  • Open Access
913 Views
16 Pages

Does Preoperative CT Improve Outcomes in Femoral Neck Fracture Fixation? A Retrospective Study

  • Ludovico Lucenti,
  • Andrea Sodano,
  • Flora Maria Chiara Panvini,
  • Andrea Vescio,
  • Giacomo Papotto,
  • Gianluca Testa and
  • Vito Pavone

21 August 2025

Background/Objectives: Femoral neck fractures are a growing concern due to their increasing incidence in both elderly and younger populations. Preoperative CT scan evaluation is often used for better understanding of fracture patterns of femoral neck...

  • Article
  • Open Access
1,761 Views
13 Pages

21 August 2025

Objectives: This case series and focused literature review address the diagnostic challenges and management strategies for patients presenting with atraumatic, isolated swelling, and stiffness of a single finger’s proximal interphalangeal (PIP)...

  • Article
  • Open Access
1 Citations
850 Views
11 Pages

The Significance of Enzymatic Cholestasis in Inflammatory Bowel Disease Patients for the Diagnosis of Primary Sclerosing Cholangitis—A Retrospective Study

  • Matei Mandea,
  • Dragos M. Oancea,
  • Mihaela C. Ghioca,
  • Speranta M. Iacob,
  • Razvan A. Iacob,
  • Ioana. G. Lupescu and
  • Liliana S. Gheorghe

21 August 2025

This retrospective longitudinal study evaluated the significance of cholestasis syndrome and the diagnosis of primary sclerosing cholangitis (PSC) in inflammatory bowel disease (IBD) patients from a tertiary center in Romania. Methods: From 2011 to 2...

  • Case Report
  • Open Access
998 Views
10 Pages

Pulmonary Infiltrates in a Non-Cystic Fibrosis Bronchiectasis Patient: A Case Report

  • Francesco Rocco Bertuccio,
  • Nicola Baio,
  • Simone Montini,
  • Valentina Ferroni,
  • Vittorio Chino,
  • Lucrezia Pisanu,
  • Marianna Russo,
  • Ilaria Giana,
  • Elisabetta Gallo and
  • Lorenzo Arlando
  • + 8 authors

21 August 2025

Background: Scedosporium apiospermum is a filamentous fungus increasingly recognized as an opportunistic pathogen in immunocompromised hosts, though rare infections in immunocompetent individuals with structural lung disease have been reported....

  • Review
  • Open Access
3 Citations
4,328 Views
27 Pages

21 August 2025

Background: Artificial intelligence (AI) is reshaping neuroimaging workflows for Alzheimer’s disease (AD) diagnosis, particularly through PET and MRI analysis advances. Since the FDA approval of Tauvid, a PET tracer targeting tau pathology, there has...

  • Article
  • Open Access
790 Views
18 Pages

Predictors of Metabolic Syndrome in Polish Women—The Role of Body Composition and Sociodemographic Factors

  • Katarzyna Dereń,
  • Magdalena Zielińska,
  • Anna Bartosiewicz and
  • Edyta Łuszczki

21 August 2025

Background: The increasing prevalence of overweight and obesity worldwide is one of the most serious public health challenges, reaching epidemic proportions. Excessive body weight is often accompanied by metabolic disorders such as insulin resistance...

  • Article
  • Open Access
1 Citations
1,980 Views
18 Pages

Updated Swiss Growth References 2025: No Height Differences, but BMI Variations Associated with Migration

  • Urs Eiholzer,
  • Anika Stephan,
  • Ilja Dubinski,
  • Christiane Fritz and
  • Cees Noordam

21 August 2025

Background/Objectives: The 2019 Swiss growth references for height, weight, and BMI were based on a large dataset from the German-speaking part of Switzerland (Cohort 2019). The current study aimed to ensure national representativeness by proportiona...

  • Article
  • Open Access
702 Views
14 Pages

Surgical Treatment of Severe Aortic Stenosis: Sutureless Versus Stented Bioprosthetic Aortic Valve Replacement

  • Alessandro Ricasoli,
  • Carmelo Mignosa,
  • Salvatore Lentini,
  • Laura Asta,
  • Adriana Sbrigata,
  • Claudia Altieri and
  • Calogera Pisano

21 August 2025

Objective: The aim of this study is to analyze the effects of sutureless aortic valve bioprosthesis implantation compared with stented conventional bioprosthesis in patients with severe aortic stenosis. This is a propensity matching institutional stu...

of 32

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
J. Clin. Med. - ISSN 2077-0383