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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis and Treatment of Ocular Surface Diseases

edited by

Stuti Misra

and

Sònia Travé-Huarte

submission deadline 20 Nov 2025 | Viewed by 43 | Submission Open

Keywords: dry eye disease; ocular surface; anterior segment imaging; biomarkers; artificial intelligence; diagnostic tools; novel therapeutic agents; anterior eye care

(This special issue belongs to the Section Ophthalmology)

Novel Approaches in Cataract and Refractive Surgery

edited by Stephen T. Armenti

submission deadline 20 Nov 2025 | Viewed by 42 | Submission Open

Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery

(This special issue belongs to the Section Ophthalmology)

Skin Wound Healing: Clinical Updates and Perspectives

edited by

András Bánvölgyi

and Norbert Kiss

submission deadline 20 Nov 2025 | Viewed by 40 | Submission Open

Keywords: dermatology; wound care; diagnosis; biomaterials; negative pressure wound therapy

(This special issue belongs to the Section Dermatology)

Clinical Procedures for Diagnosis and Treatment of Cardiovascular Diseases

edited by Ahmad Jabri, Mohammad Alqarqaz, Qais Radaideh and Ahmad Al-Abdouh

submission deadline 20 Nov 2025 | Viewed by 34 | Submission Open

Keywords: cardiovascular disease; diagnostic imaging; minimally invasive procedures; precision medicine; artificial intelligence; interventional cardiology; surgical innovations; patient outcomes; preventive cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Nov 2025 | Viewed by 29 | Submission Open

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Diagnosis and Treatment of Scoliosis and Spinal Deformity

edited by Anna Rienmueller and Kenny Yat Hong Kwan

submission deadline 20 Nov 2025 | Viewed by 23 | Submission Open

Keywords: scoliosis; spinal deformity; adolescent idiopathic scoliosis (AIS); early onset scoliosis (EOS); neuromuscular scoliosis; adult spinal deformity (ASD); operative treatment; spinal fusion; neuromonitoring in scoliosis and deformity surgery; perioperative risk factors; conservative treatment; bracing therapy; physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy; spinal biomechanics; scoliosis imaging; low-dose radiation imaging; artificial intelligence in scoliosis; 3D modelling in spinal deformity including surgical planning; predictive modelling in scoliosis progression; biomechanics of spinal curvature; growth modulation; patient-reported outcomes in scoliosis treatment

(This special issue belongs to the Section Orthopedics)

Research Advances in Coagulation Disorders

edited by Alberto Maino

submission deadline 21 Nov 2025 | Viewed by 60 | Submission Open

Keywords: coagulation; bleeding disorders; thrombosis; hemophilia; clotting disorders; hematology

(This special issue belongs to the Section Hematology)

Effect of Long-Term Insomnia on Mental Health—2nd Edition

edited by

Aleksandra Rogowska

submission deadline 21 Nov 2025 | Viewed by 57 | Submission Open

Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress

(This special issue belongs to the Section Mental Health)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

, George Konstantakopoulos and Michael Hadjulis

submission deadline 23 Nov 2025 | Viewed by 331 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Clinical Diagnosis and Management of Vestibular Disorders

edited by Sinisa Maslovara, Mario Habek and

Andro Košec

submission deadline 25 Nov 2025 | 3 articles | Viewed by 2530 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Challenges in Diagnosis and Treatment of Gynecological Malignancies in Young Adults

edited by

Oraianthi Fiste

, Dimitrios Haidopoulos and

Michalis Liontos

submission deadline 25 Nov 2025 | 2 articles | Viewed by 1998 | Submission Open

Keywords: gynecological cancers; young adults; young women; fertility; personalized care

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 Nov 2025 | 1 articles | Viewed by 364 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives

edited by

Gaetano La Rocca

Gianluca Sambataro

and Francesco Ferro

submission deadline 25 Nov 2025 | Viewed by 118 | Submission Open

Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets

(This special issue belongs to the Section Respiratory Medicine)

New Horizons in Aortic Valve Replacement

edited by Abdellaziz Dahou

submission deadline 25 Nov 2025 | Viewed by 84 | Submission Open

Keywords: aortic valve; aortic stenosis; TAVR; SAVR; valve durability; aortic valve replacement; transcatheter aortic valve replacement; surgical aortic valve replacement

(This special issue belongs to the Section Cardiology)

Interstitial Lung Diseases: New Treatments Based on Treatable Traits

edited by Francesco Amati

submission deadline 25 Nov 2025 | Viewed by 82 | Submission Open

Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Anemia: Clinical Updates in Diagnosis, Management, and Treatment

edited by

Joan-Lluis Vives-Corrons

submission deadline 25 Nov 2025 | Viewed by 66 | Submission Open

Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia

(This special issue belongs to the Section Hematology)

New Insights in Paediatric Endocrinology

edited by

Marco Fiore

submission deadline 25 Nov 2025 | Viewed by 63 | Submission Open

Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns

(This special issue belongs to the Section Clinical Pediatrics)

Recent Advances in Diagnosis and Treatment of Comorbid Disorders in Interstitial Lung Diseases

edited by

Giacomo Sica

and Domenica Francesca Mariniello

submission deadline 25 Nov 2025 | Viewed by 63 | Submission Open

Keywords: interstitial lung disease; ILD; progressive pulmonary fibrosis; artificial intelligence; management

(This special issue belongs to the Section Respiratory Medicine)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 Nov 2025 | Viewed by 55 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease

edited by

Antonio Casado-Díaz

submission deadline 25 Nov 2025 | Viewed by 51 | Submission Open

Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Updates in Reproductive Endocrinology: 2nd Edition

edited by Iwona Bojar and

Dorota Raczkiewicz

submission deadline 25 Nov 2025 | Viewed by 51 | Submission Open

Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 Nov 2025 | Viewed by 50 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Enhancing Safety and Outcomes in Complex Spine Surgery

edited by Ahmed Ramadan Sadek

submission deadline 25 Nov 2025 | Viewed by 49 | Submission Open

Keywords: spinal surgery; spinal deformity; scoliosis; sciatica; back and neck pain

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Surgical Treatment for Hepato–Pancreatic–Biliary (HPB) Diseases

edited by

Spiros G. Delis

submission deadline 25 Nov 2025 | Viewed by 49 | Submission Open

Keywords: pancreas surgery; liver resection; minimal invasive approach; virtual reality; robotic surgery; MDT

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Spinal Neurosurgery

edited by Jang-Won Yoon

submission deadline 25 Nov 2025 | Viewed by 48 | Submission Open

Keywords: minimally invasive spine surgery; lateral lumbar interbody fusion; endoscopic spine surgery; patient-reported out-comes; functional assessment; perioperative care; surgical decision-making

(This special issue belongs to the Section Clinical Neurology)

Recent Advances in Adverse Pregnancy and Neonatal Outcomes

edited by

Sae-kyung Choi

submission deadline 25 Nov 2025 | Viewed by 46 | Submission Open

Keywords: maternal and fetal; adverse pregnancy; neonatal outcomes; newborns; cesarean section

(This special issue belongs to the Section Obstetrics & Gynecology)

Ventricular Assist Devices: Clinical Advances in Practice and Future Perspectives

edited by Balakrishnan M. Mahesh

submission deadline 25 Nov 2025 | Viewed by 45 | Submission Open

Keywords: ventricular assist device; mechanical circulatory support; pulsatile pneumatic devices; microaxial intraventricular de-vices; magnetically levitated devices; cardiac transplantation; donor circulatory death; normothermic regional perfusion

(This special issue belongs to the Section Cardiology)

Minimally Invasive Laparoendoscopic Procedures in Abdominal Emergencies

edited by

Eugen Tãrcoveanu

Costel Bradea

and

Alin Mihai Vasilescu

submission deadline 25 Nov 2025 | Viewed by 43 | Submission Open

Keywords: laparoscopic surgery; robotic surgery; minimally invasive surgery; hepatobiliary surgery; pancreatic surgery; gastrointestinal surgery; general surgery; emergency surgery; trauma; recent advances in laparoscopic surgery; surgical training in laparoscopy; endoscopic surgery; the feasibility and safety of laparoscopic; endoscopic co-operative surgery for the treatment of digestive pathology

(This special issue belongs to the Section General Surgery)

Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications

edited by Ioanna Koniari

submission deadline 25 Nov 2025 | Viewed by 41 | Submission Open

Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system

(This special issue belongs to the Section Cardiology)

Treatment and Digital Outcome Assessment in Orthopaedic Trauma

edited by Benedikt Johannes Braun and

Meir Tibi Marmor

submission deadline 25 Nov 2025 | Viewed by 40 | Submission Open

Keywords: orthopaedic trauma; digital outcome assessment; wearable sensors; patient-reported outcomes; machine learning (or artificial intelligence)

(This special issue belongs to the Section Orthopedics)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 Nov 2025 | Viewed by 36 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 Nov 2025 | Viewed by 35 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology

edited by

Mohsen Ibrahim

submission deadline 25 Nov 2025 | Viewed by 29 | Submission Open

Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer

(This special issue belongs to the Section General Surgery)

New Approaches in Open and Minimally Invasive Surgery for Abdominal Oncologic Surgery

edited by

Alessandro Coppola

and Immacolata Iannone

submission deadline 25 Nov 2025 | Viewed by 29 | Submission Open

Keywords: surgical oncology; early diagnosis; minimally invasive surgery; personalized medicine; combined therapy; gastrointestinal cancer; oligometastatic cancer; peritoneal disease

(This special issue belongs to the Section General Surgery)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 Nov 2025 | Viewed by 29 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition

edited by Alessia Mattei, Rita Cataldo and

Alessandro Strumia

submission deadline 25 Nov 2025 | Viewed by 29 | Submission Open

Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit

(This special issue belongs to the Section Anesthesiology)

Clinical Innovation in Endoscopic Sinus and Anterior Skull Base Surgery

edited by

Samiul Muquit

and

Marios Stavrakas

submission deadline 27 Nov 2025 | Viewed by 45 | Submission Open

Keywords: rhinology; endoscopic anterior skull base surgery; anterior skull base surgery; endoscopic sinus surgery; chronic rhinosinusitis (CRS); otolaryngology

(This special issue belongs to the Section Otolaryngology)

Management of Complex Infective Endocarditis

edited by Shekhar Saha, Tulio Caldonazo and Mateo Marin-Cuartas

submission deadline 27 Nov 2025 | Viewed by 31 | Submission Open

Keywords: infective endocarditis; imaging; diagnosis; cardiac surgery; pathogens; antibiotic treatment; risk estimation

(This special issue belongs to the Section Cardiology)

Advances in Spine Surgery: Best Practices and Future Directions

edited by Martin N. Stienen and Stefan Motov

submission deadline 28 Nov 2025 | Viewed by 133 | Submission Open

Keywords: minimally invasive spine surgery; spinal endoscopy; spinal robotics; spinal navigation; ERAS; machine learning; artificial intelligence; complication management; revision surgery; spinal deformity; innovation; future direction

(This special issue belongs to the Section Clinical Neurology)

Innovations in Thoracic Surgery and Disease Management: Integrating Genomics, Technology, and Multidisciplinary Care

edited by

Marco Scarci

and

Savvas Lampridis

submission deadline 28 Nov 2025 | Viewed by 56 | Submission Open

Keywords: thoracic surgery; thoracic disease; genomic medicine; artificial intelligence; advanced imaging; multidisciplinary care; minimally invasive surgery; robotic surgery; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Novel Treatments for Vestibular Migraine

edited by

Teru Kamogashira

submission deadline 28 Nov 2025 | Viewed by 49 | Submission Open

Keywords: neuromodulation therapy; sympathetic nerve stimulation; CGRP-targeted therapy; dietary interventions; elimination diets; ketogenic diet; low-glycemic index diet; nutritional supplements; pathophysiology of vestibular migraine; clinical adoption of VM therapies

(This special issue belongs to the Section Otolaryngology)

Advancements in Anterior Cruciate Ligament Injury: From Diagnosis to the Return-to-Sports: 2nd Edition

edited by Alexandre Hardy and Nicolas Bouguennec

submission deadline 28 Nov 2025 | Viewed by 46 | Submission Open

Keywords: anterior cruciate ligament reconstruction (ACLR); timing of ACLR; ramp lesion; meniscal lesion; lateral extra-articular procedure

(This special issue belongs to the Section Sports Medicine)

Current Practices in Cardiovascular Perfusion and Recovery

edited by

Irbaz Hameed

submission deadline 28 Nov 2025 | Viewed by 46 | Submission Open

Keywords: organ perfusion; ex vivo perfusion; ischemia– reperfusion injury; organ recovery; transplantation; machine perfusion; organ preservation

(This special issue belongs to the Section Cardiology)

Clinical Updates in Heart Transplantation

edited by

Giacomo Bianchi

submission deadline 28 Nov 2025 | Viewed by 45 | Submission Open

Keywords: heart transplantation; ex vivo heart preservation; immunosuppression; xenotransplantation; pre-clinical models; dilated cardiomyopathy; amyloidosis; congenital heart disease

(This special issue belongs to the Section Cardiology)

Novel Diagnostic and Therapeutic Opportunities in Inflammatory and Oncological Diseases in the Gastrointestinal Tract

edited by

Adam Fabisiak

and Hubert Zatorski

submission deadline 28 Nov 2025 | Viewed by 45 | Submission Open

Keywords: cancer; inflammation; diagnosis; treatment; microbiota; gastrointestinal tract; gastroenterology; immunology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

State of the Art in Hepato-Pancreato-Biliary (HPB) Surgery

edited by

Pantelis Antonakis

and Konstantinos Bramis

submission deadline 28 Nov 2025 | Viewed by 32 | Submission Open

Keywords: hepato-pancreato-biliary (HPB) surgery; robotic surgery; laparoscopic surgery; liver resection; liver transplantation; pancreatectomy; liver thermoablation; extrahepatic cholangiocarcinoma; benign biliary disease; pancreatic neuroendocrine tumors; non-colorectal/non-neuroendocrine oligometastatic liver disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances of Breast Surgery and Reconstruction

edited by

Glenda Giorgia Caputo

and Emanuele Cigna

submission deadline 30 Nov 2025 | Viewed by 658 | Submission Open

Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery

edited by

Hidenaga Kobashi

submission deadline 30 Nov 2025 | Viewed by 577 | Submission Open

Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery

(This special issue belongs to the Section Ophthalmology)

What’s New in Cardiomyopathies: Diagnosis, Treatment and Management

edited by

Cinzia Forleo

submission deadline 30 Nov 2025 | Viewed by 250 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Pediatric Dentistry: Recent Advances, Current Issues and Future Challenges

edited by

Liliana Szyszka-Sommerfeld

and

Krzysztof Woźniak

submission deadline 30 Nov 2025 | Viewed by 116 | Submission Open

Keywords: pediatric dentistry; recent advances; current issues; future challenges; orthodontic issues; preventive strategies; access to care disparities; behavioral management; multidisciplinary collaboration; oral health

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 1101-1150 on page 23 of 28.

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