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Prostatectomy: Clinical Updates and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 779

Special Issue Editor


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Guest Editor
Department of Urology, Sapienza Università di Roma, 00191 Rome, Italy
Interests: urology; robotics; surgery; uro-oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on recent advances and future prospects in the field of prostatectomy, an important surgical procedure for the treatment of prostate cancer and other prostate-related diseases.

Robotic radical prostatectomy is an actual theme in urology. Innovation with single-port (SP) robotic radical prostatectomy has led to only a few studies and reviews. Although they investigate SP robotic radical prostatectomy, they lack enough to perform meaningful statistical analysis. However, preliminary data suggest that it is a safe procedure with comparable oncological and functional outcomes to standard surgery. We look forward to new insights into this topic.

We invite researchers from around the world to submit their work showcasing new perspectives on prostatectomy. We look forward to receiving your submissions.

Dr. Antonio Nacchia
Guest Editor

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Keywords

  • single port
  • prostatectomy
  • robotics
  • RARP
  • prostate cancer

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Published Papers (1 paper)

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Research

11 pages, 540 KiB  
Article
Radical Prostatectomy: Evolution of Surgical Techniques from Laparoscopy to Robotics
by Tomasz Syryło, Tomasz Ząbkowski, Tomasz Waldemar Kamiński, Ryszard Skiba and Hubert Andrzej Krzepkowski
J. Clin. Med. 2025, 14(10), 3444; https://doi.org/10.3390/jcm14103444 - 15 May 2025
Viewed by 646
Abstract
Background/Objectives: Radical prostatectomy is a standard treatment for localized prostate cancer. We aimed to compare perioperative outcomes and functional results between laparoscopic radical prostatectomy (LRP) and robot-assisted radical prostatectomy (RARP). Methods: A retrospective analysis was conducted on 120 patients who underwent [...] Read more.
Background/Objectives: Radical prostatectomy is a standard treatment for localized prostate cancer. We aimed to compare perioperative outcomes and functional results between laparoscopic radical prostatectomy (LRP) and robot-assisted radical prostatectomy (RARP). Methods: A retrospective analysis was conducted on 120 patients who underwent LRP (n = 60) or RARP (n = 60). Perioperative parameters, including operative time, hospitalization duration, blood transfusion rate, wound healing complications, urinary catheterization duration, urinary tract infections (UTIs), and urinary incontinence, were assessed. Statistical analyses included Student’s t-, Mann–Whitney U, and χ2 tests. Results: RARP was associated with significantly shorter operative time, compared with LRP (147.25 vs. 188.30 min, p < 0.0001). No significant differences were observed in hospitalization duration, transfusion rates, or overall complication rates. However, impaired wound healing was less frequent in the RARP group, with a 10% lower incidence, compared with the LRP group (p = 0.0946). Similarly, UTIs occurred less often in the RARP group (six vs. one cases; p = 0.0544). Urinary incontinence was significantly less frequent following RARP, with its incidence being more than twice as low, compared with the LRP group (p = 0.0032). Additionally, the RARP group had significantly lower International Prostate Symptom Scores, with a mean difference of 7.83 points, indicating improved urinary function. No significant differences were found in sexual function (IIEF-5 scores). Conclusions: RARP offers advantages over LRP, including reduced operative time, lower rates of wound healing complications, decreased incidence of urinary incontinence, and improved postoperative urinary function. Further studies with larger cohorts are warranted to confirm these findings and assess long-term functional and oncological outcomes. Full article
(This article belongs to the Special Issue Prostatectomy: Clinical Updates and Perspectives)
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