Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 73

Special Issue Editors


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Guest Editor
Department of Neurosurgery, IRCSS Humanitas Research Hospital, Via Alessandro Manzoni 56, 20089 Rozzano, Italy
Interests: spine; spinal surgery; spinal biomechanics; microneurosurgery; vertebral oncology; neuroanatomy; back pain

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Guest Editor
Spine Surgery Unit (NCH4), Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133 Milan, Italy
Interests: spine surgery; imaging; spinal surgery; spinal cord injury; neuro-oncology; tumors; computed tomography; navigation; economic analysis; biomechanics
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Guest Editor
Spine Surgery Unit, Department of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli 8, 00136 Rome, Italy
Interests: spine; spine surgery; spinal cord; microneurosurgery; cervical myelopathy; spine tumors; vertebral oncology; back pain
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Degenerative cervical myelopathy (DCM) is a significant neurological condition characterized by progressive spinal cord compression, resulting in a spectrum of debilitating symptoms. The pathophysiology of DCM is complex, involving a combination of age-related degenerative changes, leading to spinal cord compression and subsequent neurological dysfunction. The impact of DCM on patients' quality of life is substantial, affecting their ability to perform daily activities, maintain employment, and engage in social interactions. Effective management of DCM requires a multidisciplinary approach, encompassing accurate diagnosis, appropriate surgical and non-surgical interventions, and comprehensive rehabilitation.

This Special Issue aims to publish high-quality research articles and reviews that advance our understanding of the diagnosis and management of DCM. The focus will be on novel insights and innovative approaches that improve patient outcomes. In this Special Issue, we welcome original research articles and comprehensive reviews. Research areas may include, but are not limited to, the following:

  • Novel diagnostic approaches:
    • Advanced imaging techniques (e.g., high-resolution MRI, diffusion tensor imaging, and dynamic MRI);
    • Biomarkers for early detection and disease progression;
    • Clinical prediction rules for improved diagnostic accuracy.
  • Surgical interventions:
    • Minimally invasive surgical techniques;
    • Novel instrumentation and technologies;
    • Post-operative rehabilitation strategies.
  • Non-surgical management:
    • Medical management (e.g., pain management, medications);
    • Physical therapy and rehabilitation interventions;
    • Complementary and alternative therapies.
  • Epidemiology, classification, and clinical outcomes:
    • Long-term outcomes of surgical and non-surgical interventions;
    • Quality of life assessment in patients with DCM;
    • Socioeconomic impact of DCM.

We encourage submissions that address the clinical challenges faced by patients with DCM and offer innovative solutions for improved diagnosis and management.

We look forward to receiving your contributions.

Dr. Carlo Brembilla
Dr. Francesco Costa
Dr. Filippo Maria Polli
Guest Editors

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Keywords

  • degenerative cervical myelopathy (DCM)
  • cervical spondylotic myelopathy (CSM)
  • cervical spinal stenosis
  • cervical cord compression
  • MRI of the cervical spine
  • cervical spine surgery
  • physical therapy
  • rehabilitation
  • ossification of the posterior longitudinal ligament (OPLL)
  • cervical deformity (e.g., kyphosis and lordosis)
  • patient-reported out-comes
  • surgical outcome prediction

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