Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 618

Special Issue Editors

Faculty of Nursing and Health Sciences, “Iuliu Hațieganu” University of Medicine and Pharmacy in Cluj-Napoca, 400012 Cluj, Romania
Interests: echocardiography; coronary artery disease; heart failure; hypertension; intensive care in cardiology

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Guest Editor
Faculty of Medicine, University of Medicine and Pharmacy Iasi, Iasi, Romania
Interests: echocardiography; coronary artery disease; heart failure; acute pulmonary thromboembolism; intensive care in cardiology
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Special Issue Information

Dear Colleagues,

It is our honor to invite you to contribute to this Special Issue of the Journal of Clinical Medicine, entitled “Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases”. Transthoracic echocardiography is the most effective, low-cost, minimally invasive, and readily available imaging modality for the assessment of patients exhibiting cardiac symptoms. It plays a central role in identifying or ruling out suspected acute and chronic cardiac diseases. Second, echocardiography is essential in follow-up on previously diagnosed valvular disease or heart failure. In those with heart failure, it would provide meaningful information to better treat the patient. In addition, novel techniques (transesophageal, stress, contrast, myocardial strain imaging, and three-dimensional (3D), intracardiac, echocardiography) have expanded the indications in a variety of ways and a wide range of clinical situations. Bedside echocardiography is routinely used now for patients who are critically ill with known or unknown cardiac diseases in order to elucidate the etiology of cardiovascular and respiratory failures. The role of echocardiography is increasing in patients who are asymptomatic and had, for example, a family history of sudden death, or in athletes. In this Special Issue, we aim to collect original articles and reviews focusing on the role of echocardiography on the whole spectrum of diagnosis and management of cardiac diseases. Multidisciplinary manuscripts are also welcomed.

Dr. Calin Pop
Dr. Antoniu Petris
Guest Editors

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Keywords

  • echocardiography
  • cardiac diseases
  • 3D echo
  • stress
  • myocardial strain
  • intracardiac
  • subclinical cardiac disease

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Published Papers (1 paper)

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Research

10 pages, 775 KiB  
Article
The Role of Neutrophil-to-Lymphocyte Ratio and Right Ventricular Dysfunction in Indonesian Patients with COVID-19: A Retrospective Cohort Study
by Raksheeth Agarwal, Stanislaus Ivanovich Krishnanda, Oliver Emmanuel Yausep, Raka Aldy Nugraha, Gatut Priyonugroho, Siti Hertine, Sony Hilal Wicaksono, Prima Almazini, Dian Zamroni and Hary Sakti Muliawan
J. Clin. Med. 2025, 14(6), 2051; https://doi.org/10.3390/jcm14062051 - 18 Mar 2025
Viewed by 418
Abstract
Background/Objectives: The clinical impact of neutrophil-to-lymphocyte ratio (NLR) and right ventricular (RV) dysfunction on clinical outcomes in COVID-19 remains understudied in the Indonesian population. This study aims to investigate their prognostic value in hospitalized Indonesian adults with COVID-19. Methods: A retrospective [...] Read more.
Background/Objectives: The clinical impact of neutrophil-to-lymphocyte ratio (NLR) and right ventricular (RV) dysfunction on clinical outcomes in COVID-19 remains understudied in the Indonesian population. This study aims to investigate their prognostic value in hospitalized Indonesian adults with COVID-19. Methods: A retrospective cohort study was conducted at a COVID-19 referral hospital in Indonesia. We included all consecutive adults hospitalized between April 2020 and April 2021 who underwent transthoracic echocardiography (TTE) during admission. Clinical information was extracted from electronic medical records. TTE variables were defined according to the American Society of Echocardiography criteria. Statistical analyses were performed using SPSS. Ethical approval was obtained from the Institutional Review Board of Universitas Indonesia (#2022-01-135). Results: A total of 488 patients were included in this study—29 with and 459 without RV dysfunction. The mean age of the population was 54.8, with 42% being female. An NLR >4.793 was considered elevated. Elevated NLR was independently associated with RV dysfunction (OR: 3.38, p = 0.02). Older age (HR: 1.02, p = 0.01), obesity (HR: 1.85, p < 0.01), chronic kidney disease (HR: 1.69, p = 0.01), high NLR (HR: 2.75, p < 0.001), and RV dysfunction (HR: 2.07, p = 0.02) independently increased the risk of 30-day mortality by multivariate Cox regression analysis. Conclusions: In adult Indonesian patients hospitalized with COVID-19, an elevated NLR was associated with RV dysfunction, and both of these parameters increased the risk of 30-day mortality. This retrospective cohort study highlights the prognostic importance of NLR and RV dysfunction in hospitalized COVID-19 patients, providing physicians with tools to identify high-risk patients. Full article
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