Clinical Advances in Diabetes, Obesity, and Hypertension

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 311

Special Issue Editors

Special Issue Information

Dear Colleagues, 

Obesity is a major risk factor for hypertension, cardiovascular disease, and type 2 diabetes, contributing to increased morbidity and mortality. The prevalence of these conditions varies between populations and is influenced by genetic, dietary, and lifestyle factors. The effective management of these conditions often requires a multidisciplinary approach, including lifestyle modifications, pharmacotherapy, and, in some cases, surgery.

Our aim in launching this Special Issue is to highlight the importance of a comprehensive understanding of the interplay between diabetes, obesity, and hypertension and to provide valuable insights for application in clinical practice by focusing on research advances in the prevalence, prevention, and effective treatment of hypertension, diabetes, and obesity and their complications.

Through this Special Issue, we aim to achieve the following:

  1. Explore the relationships between diabetes, obesity, and hypertension;
  2. Highlight recent clinical advances in the treatment and management of these conditions;
  3. Provide insights into the mechanisms underlying these diseases and their complications;
  4. Discuss the impact of lifestyle modifications, pharmacotherapy, and surgical interventions.

Dr. Piotr Matłosz
Dr. Justyna Wyszyńska
Guest Editors

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Keywords

  • obesity
  • hypertension
  • diabetes
  • lifestyle
  • physical activity
  • risk factors

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Published Papers (1 paper)

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Research

10 pages, 512 KiB  
Article
A New Score for Metabolic Age in Type 2 Diabetes Mellitus: Physical Rating Score
by Hasan Esat Yücel, Tufan Ulcay, Özkan Görgülü, Ruken Öncü, Emre Uğuz and Erkan Dulkadiroğlu
J. Clin. Med. 2025, 14(9), 2868; https://doi.org/10.3390/jcm14092868 - 22 Apr 2025
Viewed by 195
Abstract
Background: Metabolic age (met-age), a risk marker, may vary within the same chronological age group. Its association with chronological age, waist/height ratio, obesity degree, body mass index (BMI), and physical rating score (PRS)—risk factors for type 2 diabetes—remains unexplored. Methods: A [...] Read more.
Background: Metabolic age (met-age), a risk marker, may vary within the same chronological age group. Its association with chronological age, waist/height ratio, obesity degree, body mass index (BMI), and physical rating score (PRS)—risk factors for type 2 diabetes—remains unexplored. Methods: A total of 122 type 2 diabetes patients (50 males, 72 females) were analyzed. Bioimpedance measurements were taken using the Tanita MC-780MA, alongside anthropometric data. Variables were compared, and correlations with met-age were assessed. Results: The met-age–chronological age difference was higher in females with type 2 diabetes (p < 0.001). Females also had higher BMI, obesity degree, fat mass, and waist/height ratio (p < 0.05), but lower waist/hip ratio (p < 0.001). Males showed higher PRS, muscle mass, and fat-free mass (p < 0.001). Met-age positively correlated with chronological age and negatively with PRS in both sexes (p < 0.05). According to the linear regression model, in females, the met-age was influenced positively by chronological age and waist/height ratio and negatively by PRS (R2 = 0.983). In males, it was positively influenced by chronological age, obesity grade, and BMI, but negatively by PRS (R2 = 0.974). Conclusions: Met-age correlates with chronological age and PRS in type 2 diabetes patients. It increases with advancing age and lower PRS, with waist/height ratio impacting females and BMI/obesity degree affecting males. Full article
(This article belongs to the Special Issue Clinical Advances in Diabetes, Obesity, and Hypertension)
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