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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interstitial Lung Disease: From Diagnosis to Treatment
edited by and Tomohisa Baba
submission deadline 20 Feb 2026 | 2 articles | Viewed by 4657 | Submission Open
Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Gastrointestinal Inflammation
edited by
submission deadline 20 Feb 2026 | 3 articles | Viewed by 4421 | Submission Open
Keywords: Helicobacter pylori; antibiotic resistance; COVID-19 pandemic; post-COVID era; inflammatory bowel diseases; acute gastrointestinal infections; SARS-COV-2 infection; celiac disease
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovative Approaches to the Challenges of Neurodegenerative Disease
edited by Brian T. Bicknell and
submission deadline 20 Feb 2026 | 3 articles | Viewed by 4239 | Submission Open
Keywords: neurodegenerative disease; Parkinson’ s disease; Alzheimer’ s disease; multiple sclerosis; amyotrophic lateral sclerosis
(This special issue belongs to the Section Clinical Neurology)
Clinical Trends in Cardiomyopathy
edited by Giulia Iannaccone
submission deadline 20 Feb 2026 | 1 articles | Viewed by 3769 | Submission Open
Keywords: cardiomyopathy; genetics; treatment; targeted therapy; prognosis; long-term follow up
(This special issue belongs to the Section Cardiology)
Neurosurgery: Recent Advances and New Perspectives in Skull Base Approaches
edited by Sèbastien Froelich and Matteo De Simone
submission deadline 20 Feb 2026 | 3 articles | Viewed by 3736 | Submission Open
Keywords: skull base; neuroanatomy; tumors; augmented reality; ETOA; EEA; exoscopy; endoscopy; multi-portal approaches
(This special issue belongs to the Section Clinical Neurology)
Intraocular Lenses for Cataract Surgery: Clinical Advances and Perspectives
edited by Choul Yong Park
submission deadline 20 Feb 2026 | 4 articles | Viewed by 3712 | Submission Open
Keywords: cataract surgery; intraocular lens; IOL formula; optic; complication; presbyopia; refractive
(This special issue belongs to the Section Ophthalmology)
Innovations in Perioperative Anesthesia: Advancing Non-Operating Room Anesthesia (NORA) and Regional Techniques
edited by Francesco Coppolino and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 3672 | Submission Open
Keywords: perioperative medicine; non-operating room anesthesia (NORA); ultrasound-guided regional anesthesia; fascial plane blocks; postoperative pain management
(This special issue belongs to the Section Anesthesiology)
Recent Developments in Hearing and Balance Disorders: 2nd Edition submission deadline 20 Feb 2026 | 2 articles | Viewed by 3591 | Submission Open
Keywords: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; vertigo; imbalance
(This special issue belongs to the Section Otolaryngology)
Clinical Updates in Trauma and Emergency Medicine
edited by Yong-Soo Cho and Hyun Ho Ryu
submission deadline 20 Feb 2026 | 4 articles | Viewed by 3546 | Submission Open
Keywords: emergency medicine; epidemiology; cardiovascular disease
(This special issue belongs to the Section Emergency Medicine)
Pain Management: Current Challenges and Future Prospects
edited by Gian Marco Petroni
submission deadline 20 Feb 2026 | 4 articles | Viewed by 3487 | Submission Open
Keywords: chronic joint pain; radio frequency ablation; adipose-derived mesenchimal stem cells (ADMScs); intrarticular injection; facet joint injection with ADMScs
(This special issue belongs to the Section Anesthesiology)
Colorectal Surgery: Innovative Techniques and Enhanced Patient Outcomes
edited by Filippo Carannante and Leandro Siragusa
submission deadline 20 Feb 2026 | 3 articles | Viewed by 3199 | Submission Open
Keywords: colorectal surgery; minimally invasive techniques; artificial intelligence; perioperative patient management; translational research in coloproctology
(This special issue belongs to the Section General Surgery)
Clinical Progress of Spine Surgery
edited by and Gianluca Vadalà
submission deadline 20 Feb 2026 | 2 articles | Viewed by 3188 | Submission Open
Keywords: spine surgery; rehabilitation; robotic surgery; spinal endoscopy; spinal tumor; back pain; minimally invasive surgery; spinal fusion
(This special issue belongs to the Section Clinical Neurology)
Acute Kidney Events in Intensive Care Patients
edited by Kada Klouche
submission deadline 20 Feb 2026 | 2 articles | Viewed by 3029 | Submission Open
Keywords: acute kidney events; ICU; critically ill; RRT; outcome; acute kidney disease; chronic kidney disease; bi-omarkers
(This special issue belongs to the Section Intensive Care)
State of the Art in Invasive Vascular Interventions (Second Edition)
edited by and Luca Mezzetto
submission deadline 20 Feb 2026 | 3 articles | Viewed by 2934 | Submission Open
Keywords: coronary artery interventions; non-coronary artery cardiac interventions; open surgical cardiac procedures; endo-vascular interventions; open surgical vascular procedures
(This special issue belongs to the Section Vascular Medicine)
Kidney Transplantation: State of the Art Knowledge
edited by , Georgios Geropoulos and Kyriakos Psarras
submission deadline 20 Feb 2026 | 2 articles | Viewed by 2876 | Submission Open
Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection
(This special issue belongs to the Section Nephrology & Urology)
New Perspectives in Acute Coronary Syndrome
edited by Makoto Natsumeda
submission deadline 20 Feb 2026 | 2 articles | Viewed by 2778 | Submission Open
Keywords: acute coronary syndrome; PCI; interventional cardiology; coronary imaging; antiplatelet therapy; stentless PCI strategy; CABG; revascularization
(This special issue belongs to the Section Cardiology)
Management of Pregnancy Complications: 2nd Edition
edited by Ariel Many
submission deadline 20 Feb 2026 | 2 articles | Viewed by 2642 | Submission Open
Keywords: high-risk pregnancy; preterm labor; fetal growth restriction; gestational diabetes; twins; hypertensive disorders during pregnancy; preeclampsia; IUGR; prenatal genetics; congenital anomaly detection; cesarean section; complications of labor and delivery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Diagnosis and Therapeutic Strategies for Uveal Melanoma
edited by Yong Qin
submission deadline 20 Feb 2026 | 1 articles | Viewed by 2416 | Submission Open
Keywords: uveal melanoma; immunotherapy; targeted therapy; biomarker; disease management; drug development; drug resistance
(This special issue belongs to the Section Ophthalmology)
Advancements in Cardiac Electrophysiology Through Biomedical Engineering for Abnormality Monitoring and Detection in Clinical Practice
edited by Ilaria Marcantoni and Michela Casella
submission deadline 20 Feb 2026 | 2 articles | Viewed by 2395 | Submission Open
Keywords: electrocardiogram; cardiac electrophysiology; cardiac risk index; cardiac arrhythmias; electrocardiographic alternans; long QT syndrome; heart electrical system anomalies; monitoring of heart electrical system; prevention; biomedical engineering in electrocardiology; cardiac signal processing; cardiac image processing
(This special issue belongs to the Section Cardiology)
Global Expert Views on Clinical Aesthetic Plastic Surgery
edited by and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 2385 | Submission Open
Keywords: aesthetic surgery; cosmetic surgery; dermal fillers; facial plastic surgery; soft tissue fillers; filler complications; ultrasound guided filler injection; hyaluronic acid filler
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Traumatic Brain Injury—Clinical Translational Approaches, Demographic Change, and Neuro-Critical Care
edited by and Thomas Kapapa
submission deadline 20 Feb 2026 | 1 articles | Viewed by 2384 | Submission Open
Keywords: intracranial hypertension; cerebral perfusion pressure; decompressive craniectomy; brain tissue oxygenation; brain tissue microdialysis; blood brain barrier; neuro-critical care
(This special issue belongs to the Section Brain Injury)
Advances in Knee Surgery and Musculoskeletal Rehabilitation: 2nd Edition submission deadline 20 Feb 2026 | 1 articles | Viewed by 2374 | Submission Open
Keywords: computer-assisted surgical navigation; smart cutting guides; robotic-assisted surgery; fast-track; telemedicine; tele-rehabilitation; virtual reality
(This special issue belongs to the Section Orthopedics)
New Insights in the Diagnosis, Treatment and Monitoring of Anemia, Inflammation and Infection submission deadline 20 Feb 2026 | 1 articles | Viewed by 2226 | Submission Open
Keywords: anemia; inflammation; infection; diagnostic tools; therapeutic strategies
(This special issue belongs to the Section Hematology)
Surgical Precision: The Impact of AI and Robotics in General Surgery
edited by Tamara M. H. Gall
submission deadline 20 Feb 2026 | 3 articles | Viewed by 2149 | Submission Open
Keywords: robotic surgery; artificial intelligence in surgery; surgical training; AR in surgery; 3D imaging; surgical navigation
(This special issue belongs to the Section General Surgery)
Epidemiology of Hyperglycemia in Pregnancy and Its Maternofetal Adverse Outcomes
edited by
submission deadline 20 Feb 2026 | 4 articles | Viewed by 2118 | Submission Open
Keywords: gestational diabetes; diabetes in pregnancy; risk factors; epidemiology; maternofetal adverse outcomes in pregnancies with hypergliycemia; temporal trends
(This special issue belongs to the Section Endocrinology & Metabolism)
Clinical Rehabilitation Update on Alzheimer’s Disease and Dementia submission deadline 20 Feb 2026 | 1 articles | Viewed by 2046 | Submission Open
Keywords: cognition; dementia; rehabilitation; exercise; memory; physical activity; Alzheimer’ s disease; non-pharmacological therapies
(This special issue belongs to the Section Clinical Rehabilitation)
Thrombosis: Latest Advances and Prospects
edited by Manila Gaddh
submission deadline 20 Feb 2026 | 1 articles | Viewed by 2043 | Submission Open
Keywords: thromboembolism; venous thrombosis; arterial thrombosis; anticoagulation
(This special issue belongs to the Section Hematology)
Pancreatitis: Current Perspectives on Diagnosis and Management
edited by
submission deadline 20 Feb 2026 | 2 articles | Viewed by 1980 | Submission Open
Keywords: acute pancreatitis; chronic pancreatitis; pancreatitis; pancreatic cancer; eco-endoscopy; gallstones; biliary stones
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Advances and Future Perspectives of Ischemic Stroke
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1905 | Submission Open
Keywords: acute ischemic stroke care; neuroimaging in ischemic stroke; alteplase and tenecteplase; endovascular treatments; recanalization and reperfusion; prognostication in stroke patients; blood– brain barrier in ischemic stroke; bi-omarkers in ischemic stroke; omics in stroke
(This special issue belongs to the Section Clinical Neurology)
Advances in Neurological Rehabilitation: Innovations and Clinical Insights
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1676 | Submission Open
Keywords: rehabilitation; neurology; assessment; occupational therapy; disability; inclusion
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates in Stem Cell Transplants
edited by Daniele Avenoso and Michele Malagola
submission deadline 20 Feb 2026 | 2 articles | Viewed by 1621 | Submission Open
Keywords: AML; CML; lymphoma; allo-HSCT; GVHD; MDS; AA
(This special issue belongs to the Section Hematology)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Feb 2026 | 2 articles | Viewed by 1595 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
Advanced Hysteroscopic Technology for Gynecological Disease submission deadline 20 Feb 2026 | 2 articles | Viewed by 1431 | Submission Open
Keywords: hysteroscopy; new technology; therapy; mini-invasive approach; laser; diagnosis; outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Management of Endometriosis: Evidence-Based Updated by Collective Clinical Experience and New Perspectives from Research
edited by , Arnaud Wattiez and
submission deadline 20 Feb 2026 | 2 articles | Viewed by 1405 | Submission Open
Keywords: endometriosis; guidelines; surgery; medical treatment; training; heuristics
(This special issue belongs to the Section Clinical Guidelines)
Innovations in Personalized Therapy and Clinical Outcomes for Myopia and Ocular Disorders submission deadline 20 Feb 2026 | 2 articles | Viewed by 1292 | Submission Open
Keywords: myopia; refractive errors; visual development; childhood eye disorders; vision screening; diagnostic tools in optometry; vision-related quality of life; therapeutic strategies in optometry; artificial intelligence; public health; eye care innovation; multidisciplinary vision science
(This special issue belongs to the Section Ophthalmology)
Clinical Insights and Emerging Strategies in Chronic Pain Management
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1230 | Submission Open
Keywords: chronic pain; neuropathic pain; multimodal pain management; digital health; real-world evidence; interdiscipli-nary care
(This special issue belongs to the Section Anesthesiology)
Clinical Updates and Personalized Medicine in Hepatocellular Carcinoma and Liver Transplantation
edited by Adriano Pellicelli
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1208 | Submission Open
Keywords: hepatocellular carcinoma; transarterial chemoembolization (TACE); transarterial radioembolization (TARE); liver transplant; immune checkpoint inhibitors (ICI); tyrosine kinase inhibitor; liver function assessment; Child-Pugh score; bridging to liver transplantation; immuno escape
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Breast Cancer: Symptoms, Types, Causes & Treatment
edited by Min-Jeong Cho and Sara Myers
submission deadline 20 Feb 2026 | 2 articles | Viewed by 1139 | Submission Open
Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Trends and Future Challenges in Percutaneous Coronary Intervention
edited by Deniz Mutlu
submission deadline 20 Feb 2026 | 3 articles | Viewed by 1073 | Submission Open
Keywords: PCI; IVUS; OCT; FFR; physiology; CT-guided PCI; complex PCI; CTO; bifurcation; coronary complications; mechanical circulatory support
(This special issue belongs to the Section Cardiovascular Medicine)
Deep Vein Thrombosis and Pulmonary Embolism: Clinical Treatment and Management—Second Edition submission deadline 20 Feb 2026 | 1 articles | Viewed by 1049 | Submission Open
Keywords: pulmonary embolism; thrombophilia; deep vein thrombosis; venous thromboembolism; anticoagulation therapy; thrombectomy; bleeding; cancer-associated thrombosis
(This special issue belongs to the Section Hematology)
Cardio-Oncology: Clinical Advances in Cardiotoxicity Detection, Imaging and Therapeutic Strategies submission deadline 20 Feb 2026 | 1 articles | Viewed by 1040 | Submission Open
Keywords: cardio-oncology; cardiovascular toxicity; targeted therapies; echocardiography; PET/CT
(This special issue belongs to the Section Cardiology)
Current Opinion of Reconstructive and Aesthetic Breast Surgery
edited by , Konstantin Frank and Vanessa Brébant
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1007 | Submission Open
Keywords: reconstructive breast surgery; lipofilling; microsurgery; aesthetic breast surgery; PROM; digital anthropometry; autologous fat transfer; ADM; synthetic mesh; BIA-ALCL; BII
(This special issue belongs to the Section General Surgery)
Updates on Neurosurgical Techniques, Management, and Outcomes for Intracranial Hemorrhages
edited by Bruno Splavski
submission deadline 20 Feb 2026 | 1 articles | Viewed by 965 | Submission Open
Keywords: minimally invasive neurosurgery; neuro-intervention endovascular techniques; intracranial hemorrhage; stroke; hemorrhagic; ischemic; neurosurgical decision-making; long-term outcomes in neurosurgery
(This special issue belongs to the Section Clinical Neurology)
Hepatobiliary Surgery: State of the Art and Future Perspectives
edited by and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 923 | Submission Open
Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain submission deadline 20 Feb 2026 | 1 articles | Viewed by 915 | Submission Open
Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain
(This special issue belongs to the Section Orthopedics)
Clinical Translation of Technological Innovations in Diabetes Therapeutics
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 877 | Submission Open
Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring
(This special issue belongs to the Section Endocrinology & Metabolism)
Advances in the Field of Cutaneous Malignancies: Background and Clinical Management submission deadline 20 Feb 2026 | 1 articles | Viewed by 836 | Submission Open
Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment
(This special issue belongs to the Section Dermatology)
Orthopedic Trauma: Diagnosis, Treatment and Rehabilitation
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 800 | Submission Open
Keywords: orthopedic trauma; fragility fractures; biomechanics; bone defect; pelvic ring; acetabular fractures; amputation; re-habilitation
(This special issue belongs to the Section Orthopedics)
Advances and Updates in Migraine
edited by and Carl H. Göbel
submission deadline 20 Feb 2026 | 1 articles | Viewed by 799 | Submission Open
Keywords: migraine; chronic migraine; headache disorders; CGRP antibodies; gepants; ditans; triptans; precision medicine; neuromodulation; comorbidities; disability burden; pediatric migraine; ICHD-3 classification; neurotransmitters; preventive therapy; translational headache research
(This special issue belongs to the Section Clinical Neurology)
Advances in Maternal–Fetal Medicine
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 786 | Submission Open
Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
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