Epidemiology of Hyperglycemia in Pregnancy and Its Maternofetal Adverse Outcomes

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 162

Special Issue Editor


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Guest Editor
Faculty of Physiatry, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla, 3, 50134 Florence, Italy
Interests: diabetes; epidemiology and statistics; diabetic foot; vascular complications; pathophysiology of diabetic complications; gender medicine; pregnancy and diabetes
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Special Issue Information

Dear Colleagues,

Hyperglycemia in pregnancy, including gestational diabetes, increases the risk of maternal and fetal complications at delivery, as well as metabolic and cardiovascular complications in mothers and their children. The incidence of gestational diabetes is progressively increasing globally. The causes of this increase are not yet clear: whether only from modifications in the criteria for its diagnosis or eventually from the increase in the incidence of related risk factors. Similarly, regarding adverse events, the temporal trend of pathogenetic factors has not yet been fully elucidated. Among these, for example, the incidence of macrosomia, once thought to be a hallmark of childbirth in mothers with gestational diabetes, does not seem to be increasing, although this may also be due to strategies aimed at improving metabolic control in pregnancy. Other than gestational diabetes, updated epidemiological data on the real incidence of diabetes in pregnancy, whether type 1 or 2, and its maternofetal complications are lacking. Therefore, this Special Issue centered on ‘Epidemiology of Hyperglycemia in Pregnancy and Its Maternofetal Adverse Outcomes’ is an invitation to provide updated answers to the following questions: Is the increase in the incidence of gestational diabetes due only to the change in diagnostic criteria or is it also due to the real increase in risk factors in our populations? Has the incidence of adverse maternofetal effects increased in parallel? Has the epidemiology of diabetes in pregnancy changed over time? And if so, what are the most important risk factors? All contributions from research groups on these topics are welcome and will certainly allow us to increase the level of knowledge on this important aspect concerning the health of mothers and their children.

Prof. Dr. Giuseppe Seghieri
Guest Editor

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Keywords

  • gestational diabetes
  • diabetes in pregnancy
  • risk factors
  • epidemiology
  • maternofetal adverse outcomes in pregnancies with hypergliycemia
  • temporal trends

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