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Clinical Updates in Trauma and Emergency Medicine
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Clinical Updates in Trauma and Emergency Medicine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Emergency Medicine".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 506

Special Issue Editors

Dr. Yong-Soo Cho

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Guest Editor
Chonnam National University Hospital, Chonnam National University, Gwangju, Republic of Korea
Interests: critical care; emergency medicine; epidemiology of cardiovascular disease
Dr. Hyun Ho Ryu

E-Mail
Guest Editor
Chonnam National University Medical School, Chonnam National University, Gwangju, Republic of Korea
Interests: emergency medicine; critical care

Special Issue Information

Dear Colleagues,

Trauma and emergency medicine represent critical areas of healthcare, encompassing the delivery of acute care for life-threatening conditions, rapid response strategies, and innovative treatment protocols to improve patient outcomes. Recent advancements in this field have focused on optimizing care through the integration of critical care approaches, epidemiological insights, and an improved understanding of cardiovascular emergencies. This Special Issue will address current challenges and developments, presenting original research and expert reviews on clinical practice, patient management strategies, and predictive diagnostic methodologies in trauma-related and acute emergency conditions.

Topics will include the following:

  • Advances in emergency cardiovascular care, including rapid-response protocols;
  • Epidemiological trends and disparities in trauma incidence and outcomes;
  • Critical care innovations and evidence-based interventions for severe trauma cases;
  • Novel diagnostic markers, risk stratification methods, and predictive models in emergency medicine;
  • Interdisciplinary approaches and strategies for enhancing emergency care systems.

Dr. Yong-Soo Cho
Dr. Hyun Ho Ryu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • emergency medicine
  • epidemiology
  • cardiovascular disease

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

8 pages, 209 KiB  
Article
Analysis of 46 Cases of Spontaneous Perirenal Hemorrhage: A Retrospective Observational Study
by Seon Beom Jo, Sun Tae Ahn, Mi Mi Oh, Sung Joon Park, Young-Hoon Yoon, Jong Wook Kim and Jung-Youn Kim
J. Clin. Med. 2025, 14(9), 2986; https://doi.org/10.3390/jcm14092986 - 25 Apr 2025
Viewed by 151
Abstract
Background: This study investigated the clinical features, underlying causes, and management of patients with spontaneous perirenal hemorrhage (Wunderlich syndrome; WS). Methods: We retrospectively reviewed the records of patients hospitalized for WS at a single tertiary center between 2011 and 2024. All patients [...] Read more.
Background: This study investigated the clinical features, underlying causes, and management of patients with spontaneous perirenal hemorrhage (Wunderlich syndrome; WS). Methods: We retrospectively reviewed the records of patients hospitalized for WS at a single tertiary center between 2011 and 2024. All patients were evaluated for non-traumatic perirenal hemorrhage identified on computed tomography (CT) in the emergency department. Clinical variables, including age, underlying diseases, symptoms, hemodynamic instability, and hospitalization course, were analyzed. Laboratory test results, as well as radiological and pathological findings, were reviewed. Results: The study included 46 events from 38 patients, with a median (IQR) follow-up period of 32 (4–82) months. The most common presenting symptom was flank pain, observed in 44 cases (95.7%). Renal lesions, including visible tumors, were detected in 25 cases (54.3%), while 13 cases (28.3%) exhibited perirenal hematoma without a distinct lesion. Among seven patients with hemodynamic instability (systolic blood pressure < 90 mmHg), one underwent emergency embolization, and four required emergency surgical exploration. Surgical intervention was performed in 13 cases (28.3%), all involving nephrectomy, while radiologic embolization was attempted in seven cases (15.2%), with one patient later requiring delayed nephrectomy. The final diagnosis revealed renal cell carcinoma in eight cases (six patients), angiomyolipoma in 11 cases (six patients), renal cysts in six cases, acquired cystic kidney disease in six cases, sarcoma in three cases, perivascular epithelioid cell tumor in one case, lymphoma in one case, and chronic pyelonephritis in four cases; no specific disease was identified in six cases. During follow-up, six patients died; four of these deaths were directly related to WS or its underlying etiologies. Conclusions: WS is a potentially life-threatening condition, with benign or malignant renal masses being the most common causes. Although the advancement of interventional techniques has led to an increasing number of cases being conservatively managed, the possibility of renal malignancy should always be considered. Full article
(This article belongs to the Special Issue Clinical Updates in Trauma and Emergency Medicine)
11 pages, 516 KiB  
Article
The Impact of Fluid Resuscitation on Clinical Outcomes According to Transport Time in Out-of-Hospital Cardiac Arrest Patients
by Eujene Jung, Young Sun Ro, Kyoung Jun Song, Sang Do Shin and Hyun Ho Ryu
J. Clin. Med. 2025, 14(9), 2867; https://doi.org/10.3390/jcm14092867 - 22 Apr 2025
Viewed by 174
Abstract
Background/Objectives: Current guidelines recommend fluid resuscitation only for out-of-hospital cardiac arrest (OHCA) patients with hypovolemia. This study aimed to determine whether intravenous (IV) fluid resuscitation improves survival outcomes of OHCA patients and how fluid resuscitation is influenced by the emergency medical service [...] Read more.
Background/Objectives: Current guidelines recommend fluid resuscitation only for out-of-hospital cardiac arrest (OHCA) patients with hypovolemia. This study aimed to determine whether intravenous (IV) fluid resuscitation improves survival outcomes of OHCA patients and how fluid resuscitation is influenced by the emergency medical service (EMS)-treated time interval (ETI), including scene time interval and transport time interval. Methods: EMS-treated OHCA adult patients with presumed cardiac etiology were enrolled between 2018 and 2019. The main exposure was IV fluid resuscitation by an EMS provider during transportation. The main outcomes were survival to discharge and neurological recovery. Multivariable logistic regression analysis calculated adjusted odd ratios (aORs). Interaction analysis between IV fluid resuscitation and ETI was also performed. Results: Of 29,228 eligible patients, 13,683 (46.8%) patients received IV fluid resuscitation. Patients receiving IV fluid resuscitation had a significantly higher likelihood of survival to discharge (aOR [95% confidence interval, CI]: 1.15 [1.01–1.32]). Considering the interaction effects between IV fluid resuscitation and ETI for survival to discharge, aOR (95% CI) was 1.20 (1.02–1.43) for patients with an ETI > 16 min and <30 min and 1.48 (1.09–2.01) for patients with an ETI of >31 min (p for interaction <0.01) compared to ETI < 15 min, used as a reference. Conclusions: IV fluid resuscitation improved survival to discharge in OHCA patients, and this benefit was maintained only with the ETI > 16 min. Full article
(This article belongs to the Special Issue Clinical Updates in Trauma and Emergency Medicine)
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