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JCM
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Hepatobiliary Surgery: State of the Art and Future Perspectives
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Hepatobiliary Surgery: State of the Art and Future Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 555

Special Issue Editors

Dr. Teresa Perra

E-Mail Website
Guest Editor
Department of Medicine, Surgery and Pharmacy, Unit of General Surgery, University of Sassari, 07100 Sassari, Italy
Interests: pancreatic cancer; pancreatic ductal adenocarcinoma; pancreatic surgery; hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; colorectal surgery; surgical oncology
Special Issues, Collections and Topics in MDPI journals
Prof. Alberto Porcu

E-Mail Website
Guest Editor
Department of Medicine, Surgery and Pharmacy, Unit of General Surgery, University of Sassari, 07100 Sassari, Italy
Interests: pancreatic cancer; pancreatic ductal adenocarcinoma; pancreatic surgery; hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; colorectal surgery; surgical oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hepatobiliary surgery is a complex procedure that often requires personalized surgical planning. A heterogeneous group of diseases, from benign conditions to primary and metastatic tumors, can be treated with hepatobiliary surgery. A careful evaluation of the patient is essential. When surgery is indicated, it is important to assess the future liver remnant (FLR) volume and function in order to plan the amount of liver to be resected. Anatomical study is essential in visualizing a hepatic lesion and its relationship with neighboring structures (e.g., hepatic arteries, hepatic veins, the portal vein and its branches, the biliary tree, other organs, and the lymph nodes). Anomalies and variants should be studied during surgical planning. Patients with an insufficient FLR could benefit from portal vein embolization, generating compensatory hypertrophy, allowing the resection of hepatobiliary tumors initially defined as unresectable.

Our aim for this Special Issue is to provide an overview of the current evidence and future perspectives in hepatobiliary surgery. Researchers in the field of hepatobiliary surgery are encouraged to submit an original article or review to this Special Issue, sharing experiences and discussing surgical approaches.

Dr. Teresa Perra
Prof. Alberto Porcu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hepatobiliary surgery
  • cholangiocarcinoma
  • hepatocellular carcinoma
  • liver metastases
  • benign liver lesions

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Published Papers (1 paper)

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Research

13 pages, 847 KiB  
Article
Examining the Branching Patterns of the Hepatis Portae Vena with Computed Tomography Images
by Bilge Turkmen, Mehmet Tugrul Yilmaz, Duygu Akin Saygin and Cengiz Kadiyoran
J. Clin. Med. 2025, 14(14), 4835; https://doi.org/10.3390/jcm14144835 - 8 Jul 2025
Viewed by 286
Abstract
Background/Objectives: The present study aimed to examine the branching pattern images of the Hepatis Portae Vena (HPV), which is one of the vascular structures of the liver, with Computed Tomography (CT), and to uncover the surgical and radiological importance of the variations. Methods: [...] Read more.
Background/Objectives: The present study aimed to examine the branching pattern images of the Hepatis Portae Vena (HPV), which is one of the vascular structures of the liver, with Computed Tomography (CT), and to uncover the surgical and radiological importance of the variations. Methods: The HPV branching patterns on CT images of healthy liver of 996 individuals (47.8% male, 52.2% female) between the ages of 20 and 59 were evaluated according to previously determined definitions. The division of the main branch of the HPV into ramus (r.), dexter, and r. sinister and the later division of r. dexter into r. anterior and r. posterior branches were called Type I-a, other main branch variations were called Type II-a, Type III-a, and Type IV-a, and the r. dexter variations were called Type V-b, Type VI-b, Type VII-b, and Type VIII-b. Also, all individuals in the present study were examined under four age groups as 20–29, 30–39, 40–49, 50–59, and the data were analyzed in the SPSS 21 software. Results: Type I-a (73.1%) was detected most frequently in all individuals, but Type VI-b (0.1%) and Type VII-b (0.1%) were detected least frequently. Following Type I-a, Type II-a (10.6%), Type III-a (8.2%), and Type V-b (5.5%) were detected, respectively. No statistically significant differences were detected between gender and age groups in terms of the frequency of HPV types (p > 0.05). Conclusions: We believe that accurate knowledge and definition of HPV anatomy will guide liver surgeries and interventional radiology, which are the cornerstones of the treatment of liver diseases. Full article
(This article belongs to the Special Issue Hepatobiliary Surgery: State of the Art and Future Perspectives)
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