Innovative Approaches to the Challenges of Neurodegenerative Disease

Dear Colleagues, 

The aging process, while not a disease in itself, can be accompanied by some age-related changes that can occur during the lifespan at many levels. These changes carry with them an increased risk for a number of age-related diseases and degenerative conditions in humans, such as Parkinson’s disease, Alzheimer’s disease, age-related dementia, amyotrophic lateral sclerosis, and multiple sclerosis, as well as depression, and anxiety. In the context of improved healthspan, as opposed to lifespan, it is crucial that these age related neurodegenerative diseases be effectively treated in order to improve quality of life and increase resilience to age-related diseases. Evidence suggests that a multidisciplinary approach to diseases is needed in order to achieve the best results. The disease response to therapeutic interventions interacts with social and behavioral factors such as environmental exposure, healthy or unhealthy behaviors, social relationships, and existing comorbidities. This Special Issue aims to present recent advances in the development of new interventions, from molecular interventions all the way to environmental/social or rehabilitation strategies, to realize the best outcomes in the treatment of neurodegenerative diseases. Research data, new ideas, and discussions of potential interventions that modulate disease responses in an aging context are welcome. Original papers, systematic reviews, and meta-analyses are welcome.

Dr. Brian T. Bicknell
Guest Editor

Prof. Dr. Ann Liebert
Co-Guest Editor

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