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Innovations in Personalized Therapy and Clinical Outcomes for Myopia and Ocular Disorders

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 215

Special Issue Editor


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Guest Editor
ISEC LISBOA—Instituto Superior de Educação e Ciências,1750-179 Lisboa, Portugal
Interests: myopia; binocular vision; epidemiology; eye disorders; refractive errors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to explore the latest advances in personalized therapy and clinical outcomes for myopia and other ocular conditions. With the global prevalence of myopia rising sharply—particularly among children and young adults—there is an urgent need for effective, individualized interventions. At the same time, a wide range of ocular disorders continue to pose significant public health challenges worldwide.

We are particularly interested in clinical approaches to diagnosis, treatment, and management, including pharmacological, optical, surgical, and behavioral strategies. Contributions that address innovations in diagnostics, digital tools, artificial intelligence, and sustainability in eye care are especially welcome.

By bringing together multidisciplinary perspectives, this Special Issue seeks to bridge the gap between research and clinical practice, promote collaborative innovation, and highlight both emerging technologies and persistent challenges in the field. We invite original research articles and comprehensive reviews that contribute to advancing individualized care and improving clinical outcomes in myopia and other visual disorders.

Dr. Clara Martinez-Perez
Guest Editor

Manuscript Submission Information

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Keywords

  • myopia
  • refractive errors
  • visual development
  • childhood eye disorders
  • vision screening
  • diagnostic tools in optometry
  • vision-related quality of life
  • therapeutic strategies in optometry
  • artificial intelligence
  • public health
  • eye care innovation
  • multidisciplinary vision science

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Published Papers (1 paper)

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Research

11 pages, 1576 KiB  
Article
Comparing Close-Field and Open-Field Autorefractometry and Subjective Refraction
by Veronica Noya-Padin, Noelia Nores-Palmas, Belen Sabucedo-Villamarin, Maria J. Giraldez, Eva Yebra-Pimentel and Hugo Pena-Verdeal
J. Clin. Med. 2025, 14(16), 5680; https://doi.org/10.3390/jcm14165680 - 11 Aug 2025
Viewed by 140
Abstract
Background/Objectives: Autorefractometers are valuable tools in clinical practice, but their accuracy is often questioned, especially in the pediatric population. This study aimed to compare refraction data from open-field and close-field autorefractometers and subjective refraction without using cycloplegia. Methods: A total of [...] Read more.
Background/Objectives: Autorefractometers are valuable tools in clinical practice, but their accuracy is often questioned, especially in the pediatric population. This study aimed to compare refraction data from open-field and close-field autorefractometers and subjective refraction without using cycloplegia. Methods: A total of 50 eyes of 50 participants (19 males and 31 females, 11.8 ± 1.56 years) were evaluated. In a single visit, objective refraction was performed using NVision-K 5001 (open-field) and Visionix VX120 (close-field) autorefractometers, and subjective refraction using the fogging technique. Differences between procedures were assessed for sphere, spherical equivalent, and cylindrical vectors J0 and J45 using the Friedman test, followed by the post hoc Wilcoxon test as needed. Results: Significant differences were found in the sphere between the three procedures (all p ≤ 0.032). For the spherical equivalent, the Visionix VX120 differed significantly with the other two techniques (both p < 0.001), whereas no significant differences were found between NVision-K 5001 and subjective refraction (p = 0.193). Finally, no significant differences were observed for J0 and J45 vectors among the procedures (both p ≥ 0.166). Conclusions: There are certain discrepancies between autorefractometers and the subjective assessment of refractive error, most evident in measurements taken with the close-field device, possibly due to greater accommodative stimulation. However, in contexts such as visual screening or as a preliminary guide in the clinic, the values obtained by autorefractometry can provide useful information. Full article
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