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Global Expert Views on Clinical Aesthetic Plastic Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 837

Special Issue Editors

Yonsei E1 Plastic Surgery Clinic, Anyang, Republic of Korea
Interests: aesthetic surgery; cosmetic surgery; dermal fillers; facial plastic surgery; soft tissue fillers; filler complications; ultrasound guided filler injection

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Guest Editor
Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea
Interests: aesthetic plastic surgery; wound care; reconstructive surgery; wound healing

Special Issue Information

Dear Colleagues,

Aesthetic medicine has undergone tremendous advancements over the years. The development of botulinum toxin and hyaluronic acid fillers, along with various biostimulators, has led to significant progress in the field of facial rejuvenation. Additionally, the discovery of the superficial musculoaponeurotic system (SMAS) has greatly enhanced lifting procedures. As the field of plastic surgery has evolved over the years, patients have increasingly sought more minimally invasive procedures, which has further propelled the advancement of aesthetic medicine. Recently, even minimally invasive plastic surgeries have begun to incorporate direct ultrasound guidance to better prevent complications, and as technology continues to advance, less invasive procedures that are more beneficial to patients are being developed. However, many procedures that lack scientific validation are still being performed, often driven by the ignorance of physicians and the desires of patients. At this juncture, it is crucial for physicians to approach aesthetic medicine with a scientific perspective, ensuring that new procedures and products are validated through rigorous scientific methods. Therefore, plastic surgeons, dermatologists, and cosmetic doctors are encouraged to submit their clinical studies and research as original articles or reviews to this Special Issue.

Dr. Won Lee
Dr. Seong Hwan Kim
Guest Editors

Manuscript Submission Information

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Keywords

  • aesthetic surgery
  • cosmetic surgery
  • dermal fillers
  • facial plastic surgery
  • soft tissue fillers
  • filler complications
  • ultrasound guided filler injection
  • hyaluronic acid filler

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Published Papers (1 paper)

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Research

15 pages, 1190 KB  
Article
Efficacy and Safety of a Stabilized Composition of 26 mg/mL of High Molecular Weight Hyaluronic Acid for Aesthetic Applications
by Basste Hadjab, Samuel Gavard Molliard, Jérémie Bon Bétemps, Marco Cerrano, Francesco de Boccard and Alexandre Finke
J. Clin. Med. 2025, 14(17), 6015; https://doi.org/10.3390/jcm14176015 - 26 Aug 2025
Viewed by 160
Abstract
Background: The growing demand for minimally invasive aesthetic procedures highlights the need for innovative injectable solutions that target skin aging beyond volumization. Hyaluronic acid (HA)-based fillers remain a cornerstone of aesthetic treatments, but traditional formulations often offer limited benefits in improving skin quality [...] Read more.
Background: The growing demand for minimally invasive aesthetic procedures highlights the need for innovative injectable solutions that target skin aging beyond volumization. Hyaluronic acid (HA)-based fillers remain a cornerstone of aesthetic treatments, but traditional formulations often offer limited benefits in improving skin quality parameters such as elasticity. This study evaluated the efficacy and safety of an injectable formulation composed of 2.6% high molecular weight hyaluronic acid (H-HA) and 3.2% sorbitol, designed to improve skin biomechanical properties through subcutaneous administration. Methods: In this single-center, open-label, single-arm clinical trial, 86 participants aged 35 to 70 years received a single injection in the facial region. Clinical outcomes were assessed at baseline (day 0), one month (M1), and four months (M4) post-injection using the Global Aesthetic Improvement Scale (GAIS), instrumental Cutometer® measurements of skin elasticity and recovery, and patient satisfaction questionnaires. Results: Significant improvements in skin elasticity and recovery were observed at M4 following a single administration. The product was well tolerated, with only mild and transient injection site reactions observed. Conclusions: These exploratory findings support the clinical benefit of combining high-concentration H-HA with sorbitol to enhance skin quality in a safe and minimally invasive manner. These preliminary results position this formulation as a promising option for facial rejuvenation, targeting biomechanical improvement through a single-session injectable protocol. Full article
(This article belongs to the Special Issue Global Expert Views on Clinical Aesthetic Plastic Surgery)
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