Advances and Updates in Migraine
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 11
Special Issue Editors
Interests: migraine; headache; neurology; pain management; diagnosis; comorbidity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Migraine is the most prominent headache disorder and ranks third among all diseases worldwide, affecting nearly 15% of the global population annually. It is most prevalent in women aged 30 to 40 and is more common than diabetes, asthma, and epilepsy combined. Chronic migraine alone impacts approximately 2% of the world’s population. The WHO lists migraine as the leading cause of disability under the age of 50, especially in women. Headache disorders account for over 75% of all years lived with disability due to neurological diseases—surpassing stroke, dementia, Parkinson’s disease, multiple sclerosis, and epilepsy. Despite this immense burden, headache disorders are still underdiagnosed and undertreated. Comorbidities such as depression, anxiety, cardiovascular disease, and stroke—especially in young women—underline the urgent need for improved care structures.
This Special Issue aims to highlight cutting-edge advances in migraine research, diagnosis, and treatment. We welcome contributions addressing novel pathophysiological insights, genetic risk factors, precision medicine approaches, and innovations in acute and preventive therapies, including CGRP-antibodies, gepants, ditans, and neuromodulation. By bringing together clinical and translational research, this Special Issue seeks to catalyze change and mobilize the scientific community to reduce the individual and societal burden of migraine and headache disorders.
Prof. Dr. Hartmut Göbel
Dr. Carl H. Göbel
Guest Editors
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Keywords
- migraine
- chronic migraine
- headache disorders
- CGRP antibodies
- gepants
- ditans
- triptans
- precision medicine
- neuromodulation
- comorbidities
- disability burden
- pediatric migraine
- ICHD-3 classification
- neurotransmitters
- preventive therapy
- translational headache research
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