Recent Developments in Hearing and Balance Disorders: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 805

Special Issue Editor


E-Mail Website
Guest Editor
Department of Otolaryngology, Hospital Can Misses, Ibiza, Spain
Interests: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; balance; vertigo
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to invite you to contribute to the Special Issue entitled "Recent Developments in Hearing and Balance Disorders: 2nd Edition". This is one new volume, we published six papers in the first volume. For more details, please visit: https://www.mdpi.com/journal/jcm/special_issues/1ME66052P9.

Patients with the ear diseases of hearing loss or imbalance currently have effective interventions available to them throughout their lifetime. Revolutionary advances have been made in the field of hearing and balance technology in recent decades, such as implants, diagnostics and telemedicine, with innovations that allow for the diagnosis of ear diseases (cochlear and vestibular disorders) and hearing loss at any age. Medical and surgical treatment, hearing aids, cochlear and vestibular im-plants, therapy (intratympanic delivery of treatments) or rehabilitation, sign language and subtitling are solutions that allow people to with ear diseases or hearing loss, meaning they are able to access education and communication, thus having the opportunity to develop their potential.

The fundamental objective of this Special Issue dedicated to outlining the recent developments in hearing and balance disorders is to make available to readers the most recent advances in the diagnosis, prognosis and treatment of hearing loss and balance, as well as its effects on communication, cognitive impairment, social isolation or even the effects of impaired balance such as falls, and the frequent association of hearing disorders (hearing loss, tinnitus) with others closely related diseases, such as vertigo and imbalance. This Special Issue also includes studies focused on the relationship between chronic inflammatory and autoimmune diseases with audiovestibular manifestations.

Dr. Juan Carlos Amor-Dorado
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ear
  • otology
  • audiology
  • hearing disorders
  • deafness
  • hearing loss
  • autoimmunity
  • ENT
  • inflammation
  • vertigo
  • imbalance

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

21 pages, 2146 KiB  
Perspective
Preclinical Models to Study the Molecular Pathophysiology of Meniere’s Disease: A Pathway to Gene Therapy
by Prathamesh T. Nadar-Ponniah and Jose A. Lopez-Escamez
J. Clin. Med. 2025, 14(5), 1427; https://doi.org/10.3390/jcm14051427 - 20 Feb 2025
Viewed by 662
Abstract
Background: Meniere’s disease (MD) is a set of rare disorders that affects >4 million people worldwide. Individuals with MD suffer from episodes of vertigo associated with fluctuating sensorineural hearing loss and tinnitus. Hearing loss can involve one or both ears. Over 10% of [...] Read more.
Background: Meniere’s disease (MD) is a set of rare disorders that affects >4 million people worldwide. Individuals with MD suffer from episodes of vertigo associated with fluctuating sensorineural hearing loss and tinnitus. Hearing loss can involve one or both ears. Over 10% of the reported cases are observed in families, suggesting its significant genetic contribution. The condition is polygenic with >20 genes, and several patterns of inheritance have been reported, including autosomal dominant, autosomal recessive, and digenic inheritance across multiple MD families. Preclinical research using animal models has been an indispensable tool for studying the neurophysiology of the auditory and vestibular systems and to get a better understanding of the functional role of genes that are involved in the hearing and vestibular dysfunction. While mouse models are the most used preclinical model, this review analyzes alternative animal and non-animal models that can be used to study MD genes. Methods: A literature search of the 21 genes reported for familial MD and the preclinical models used to investigate their functional role was performed. Results: Comparing the homology of proteins encoded by these genes to other model organisms revealed Drosophila and zebrafish as cost-effective models to screen multiple genes and study the pathophysiology of MD. Conclusions: Murine models are preferred for a quantitative neurophysiological assessment of hearing and vestibular functions to develop drug or gene therapy. Full article
(This article belongs to the Special Issue Recent Developments in Hearing and Balance Disorders: 2nd Edition)
Show Figures

Graphical abstract

Back to TopTop