Canonical and Noncanonical Inflammasomes in Inflammation and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 11
Special Issue Editor
Interests: inflammation; inflammatory/autoimmune diseases; noncanonical inflammasomes; macrophage; anti-inflammatory therapeutics; signaling transduction; immunology; molecular biology; biochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The inflammasome is an intracellular protein complex that provides a molecular platform for inflammatory responses to a variety of the pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs). The inflammasome is classified into canonical and noncanonical inflammasomes, and has been demonstrated to play a crucial role in inflammation and diseases. However, the roles of both canonical and noncanonical inflammasomes, as well as how their dysregulation contributes to inflammatory responses and diseases, are still not well understood and require further investigation.
This Special Issue aims to investigate the regulatory roles of both canonical and noncanonical inflammasomes in inflammation and diseases and to provide insights into the development of new anti-inflammatory therapeutics by targeting inflammasomes.
Potential topics include but are not limited to
- the roles of canonical and noncanonical inflammasomes in inflammatory responses and human diseases,
- the underlying mechanisms,
- identifying and validating novel molecules interplaying with inflammasomes,
- evaluating anti-inflammatory effects by targeting inflammasomes, and
- developing potential inflammasome-targeted therapeutics.
Dr. Young-Su Yi
Guest Editor
Manuscript Submission Information
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Keywords
- canonical
- noncanonical
- inflammasome
- inflammation
- human diseases
- anti-inflammatory therapeutics
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