miRNAs in Cancers: From Molecular Biology to Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 722
Special Issue Editor
Interests: S-adenosylmethionine; cancer; epigenetics; miRNA
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Epigenetic mechanisms are crucial for the proper development and maintenance of tissue-specific gene expression patterns in mammals. Epigenetic modifications, such as changes in DNA methylation, RNA modifications, and histone alterations, can result in the dysregulation of microRNA (miRNA) genes and malignant cellular transformation. These modifications are both heritable and reversible. Additionally, miRNAs can influence epigenetic-modifying enzymes, creating a three-way regulatory feedback loop known as “epi-miR-epi”. Modifying and reversing pathological miRNA expression holds promise for the development of therapeutic strategies.
This Special Issue is focused on “miRNAs in Cancers: From Molecular Biology to Treatment”. We invite researchers to submit original research and review articles that explore the role of miRNAs in cancer development.
Dr. Laura Mosca
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- miRNA
- epigenetic
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