Recombinant Proteins and Antibody Engineering for Diagnostic and Treatment of Emerging Infectious Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 43
Special Issue Editor
Interests: recombinant proteins; antibody engineering; hemorrhagic fevers; tuberculosis; emerging infectious diseases; diagnostics; therapeutic antibodies
Special Issue Information
Dear Colleagues,
Recombinant protein and antibody engineering have become central to the development of innovative tools for the prevention, diagnosis, and treatment of emerging and neglected infectious diseases. Advances in protein expression systems and antibody design have enabled the generation of highly specific, stable, and non-immunogenic molecules that are deployable in both therapeutic and diagnostic contexts.
While recent global attention has focused on pandemics, such as COVID-19, the need for novel interventions remains critical for long-standing public health threats, including tuberculosis, Old World and New World hemorrhagic fevers (such as Lassa, Crimean-Congo, and Junín viruses), and other neglected viral infections. These diseases disproportionately affect low-resource populations and are often underserved by current biomedical technologies.
This Special Issue will focus on cutting-edge developments in recombinant protein and monoclonal antibody engineering directed against emerging and neglected pathogens. We welcome original research and review articles addressing antibody-based therapeutics, novel antigen design, novel antibody formats, and diagnostic innovations with relevance to both acute outbreaks and endemic diseases.
Dr. Gustavo Helguera
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- recombinant proteins
- antibody engineering
- monoclonal antibodies
- hemorrhagic fevers
- tuberculosis
- emerging infectious diseases
- neglected viruses
- diagnostics
- therapeutic antibodies
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