ijms-logo

Journal Browser

Journal Browser

Antibacterial Nanomaterials for Medicinal Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 799

Special Issue Editor


E-Mail Website
Guest Editor
Graduate Institute of Nanomedicine and Medical Engineering, Taipei Medical University, 250 Wu-Hsing Street, Taipei 11031, Taiwan
Interests: nanomaterials; antibacterial; nanomedicine; nanotechnology; biomedical applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rise of antibacterial resistance and the increasing prevalence of difficult-to-treat infections have posed significant challenges to global healthcare systems. With the overuse of traditional antibiotics, the development of innovative solutions to combat bacterial infections has become imperative. Nanotechnology has emerged as a promising frontier in this battle, offering unique advantages through the design and application of antibacterial nanomaterials. These nanomaterials possess exceptional properties, including unique structural and optical characteristics, controlled release capabilities, and the ability to target specific pathogens, making them highly effective for medicinal applications.

This Special Issue aims to explore the latest advancements in antibacterial nanomaterials and their role in various medical fields. Topics of interest include, but are not limited to, the synthesis and characterization of novel nanomaterials, their mechanisms of antibacterial action, applications in drug delivery systems, wound healing, coatings for medical devices, and strategies to address toxicity and biocompatibility concerns. We invite contributions of research articles, reviews, and perspectives that highlight the potential of nanomaterials to revolutionize medicinal applications.

Prof. Dr. Tsung-Rong Kuo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology
  • antibacterial
  • nanomaterials
  • toxicity
  • biocompatibility
  • medicinal applications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

16 pages, 2027 KB  
Article
Unveiling the Antibacterial Efficacy and Mechanistic Insights of MnO2 Nanoparticles for Advanced Therapeutic Applications
by Istikhori Fitriannisa, Hanny Tika Draviana, Cheng-Pei Hsieh, Muhammad Saukani, Kai-Yi Tzou and Tsung-Rong Kuo
Int. J. Mol. Sci. 2025, 26(18), 9104; https://doi.org/10.3390/ijms26189104 - 18 Sep 2025
Viewed by 611
Abstract
Pathogenic bacterial infections pose serious health risks, underscoring the need for timely treatments. Manganese dioxide (MnO2) nanoparticles (NPs) have attracted considerable attention owing to their outstanding chemical stability, favorable biocompatibility, high reactivity, and catalytic ability to decompose hydrogen peroxide, making them [...] Read more.
Pathogenic bacterial infections pose serious health risks, underscoring the need for timely treatments. Manganese dioxide (MnO2) nanoparticles (NPs) have attracted considerable attention owing to their outstanding chemical stability, favorable biocompatibility, high reactivity, and catalytic ability to decompose hydrogen peroxide, making them promising antibacterial agents. A clear understanding of their antibacterial mechanisms is essential for evaluating their therapeutic potential in clinical settings. In this study, MnO2 NPs were synthesized by reacting potassium permanganate (KMnO4) with poly(allylamine hydrochloride) (PAH), ensuring complete conversion to MnO2 NPs. The resulting NPs were characterized for their physicochemical properties, and their antibacterial activity against E. coli and S. aureus was evaluated using growth curve assays and reactive oxygen species (ROS) quantification. Results indicated the killing efficiency of MnO2 NPs increased with exposure time and concentration, reflecting high susceptibility of both bacterial strains. Scanning electron microscopy (SEM) analysis revealed that the interaction between MnO2 NPs and bacterial cells caused significant disruption of cell wall integrity. This study provides a valuable platform for evaluating MnO2 nanoparticles as antibacterial agents and for exploring their mechanisms in medical applications. Full article
(This article belongs to the Special Issue Antibacterial Nanomaterials for Medicinal Applications)
Show Figures

Graphical abstract

Back to TopTop