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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Gut Microbiota and Immunity

edited by

Maria Pascual

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2540 | Submission Open

Keywords: gut; microbiota; immune response; infectious disease; cancer; brain function; metabolism; endocrine signaling; pathological conditions; therapy

(This special issue belongs to the Section Molecular Immunology)

Molecular and Cellular Mechanisms on Autism Spectrum Disorder

edited by

Roberto Canitano

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2526 | Submission Open

Keywords: autism spectrum disorders; synaptic abnormalities; glutamatergic and GABA-targeted treatments

(This special issue belongs to the Section Molecular Neurobiology)

Immunometabolic Disorders in Aging and Disease

edited by

Yury Ladilov

and

Maria Luisa Barcena

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2516 | Submission Open

Keywords: aging; immunometabolism; immunoaging; metainflammation; AMPK; mTOR; sirtuins; age-related chronic diseases; inflammation; longevity; mitophagy; autophagy; mitochondrial function; exercise; fasting; microbiome

(This special issue belongs to the Section Molecular Immunology)

Functional Role of Non-coding RNAs in Cancer: Inside and outside Cells

edited by

Simone Anfossi

and

Linda Fabris

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2512 | Submission Open

Keywords: ncRNAs; gene expression regulation; biological functions; extracellular vesicles; intercellular communication; cancer progression; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

New Technologies and Applications in Proteomics Research

edited by Charles Streckfus

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2503 | Submission Open

Keywords: proteomic; protein

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Rare Diseases Biomarkers

edited by

Andrea Bernini

submission deadline 30 Jun 2024 | 4 articles | Viewed by 2355 | Submission Open

Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

State-of-the-Art Antimicrobial Peptides in the Era of Antibiotic Resistance

edited by

Surajit Bhattacharjya

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2349 | Submission Open

Keywords: antimicrobial peptides; host defense peptides; structrues; design of antimcrobial peptides; membrane interacitons; protein complex

(This special issue belongs to the Section Molecular Biophysics)

Molecular Biology of the Endocannabinoid System 2.0

edited by

Deanne H. Hryciw

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2346 | Submission Open

Keywords: cannabinoid receptors; cannabinoid signalling; cannabinoid therapeutics; physiology; development; disease; organs

(This special issue belongs to the Section Molecular Biology)

Research Progress of Chitin and Chitosan Derivatives

edited by

Már Másson

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2308 | Submission Open

Keywords: chemical synthesis; process development; structure– activity– relationship; structure– property– relationship; alkylation; acylation; crosslinking; chitin and chitosan derivatives; chitin and chitosan conjugates

(This special issue belongs to the Section Materials Science)

Current Developments in Glioblastoma Research and Therapy

edited by

Aleksandra Majchrzak-Celińska

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2279 | Submission Open

Keywords: diagnostic; prognostic and predictive biomarkers of glioblastoma; ways to target glioma stem cells; targeting glioblastoma-related signaling pathways; epigenetics of glioblastoma; treatment resistance mechanisms; novel treatment options for glioblastoma; combinatorial therapies; immunotherapy; nanotherapy; the application of CRISPR/Cas9 in glioma research; molecular testing of long-term glioblastoma survivors

(This special issue belongs to the Section Molecular Neurobiology)

Heartfulness: Contributors of Healthy and Unhealthy Cardiac Aging

edited by

Susana P. Pereira

and Laura A. Cox

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2219 | Submission Open

Keywords: cardiac development; gene regulation; epigenetics; genomics; integrated omics; accelerated aging; cardiac metabolism; cardiac regeneration and repair; cardiovascular diseases; cutting-edge techniques; cardiac imaging; regenerative mechanisms; pathophysiology of cardiovascular disease; cardiac endothelium; cardiomyocytes; cardiovascular computational modeling; cardiovascular informatics; transgenerational inheritance; life expectancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Genomics for Translational Research in Cancer

edited by

Ioana Berindan-Neagoe

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2182 | Submission Open

Keywords: cancer; translational medicine; genomics; diagnostics and prognostics; targeted therapy; immunotherapy; non-coding RNAs; tumor microenvironment

(This special issue belongs to the Section Molecular Genetics and Genomics)

A Commemorative Issue in Honor of József Szejtli: Advances in Cyclodextrin Chemistry and Its Applications

edited by Éva Fenyvesi,

Lajos Szente

and

Gustavo González-Gaitano

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2178 | Submission Open

(This special issue belongs to the Section Materials Science)

Advances in Homeostasis and Metabolism in Health and Disease

edited by Marc Schneeberger

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2153 | Submission Open

Keywords: neurobiology of homeostasis; peripheral organ metabolism; body-brain crosstalk; diabetes; metabolic syndrome

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Advances in Hypercapnia

edited by Masahiko Shigemura

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2145 | Submission Open

Keywords: carbon dioxide (CO2); hypercapnia; CO2 sensing mechanisms; hypercapnia-mediated signal; transduction pathways; beneficial effects of hypercapnia; detrimental effects of hypercapnia; humans; mammals; flies; nematodes; plants; marine animals

(This special issue belongs to the Section Molecular Biology)

Molecular Trends and Prospects in Plant-Pathogen Interactions

edited by

Tao Chen

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2128 | Submission Open

(This special issue belongs to the Section Molecular Plant Sciences)

Neutrophil Extracellular Traps (NETs) in Immunity and Diseases 2.0

edited by

Jasmin Knopf

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2121 | Submission Open

Keywords: neutrophils; neutrophil functions; neutrophil extracellular traps (NETs); NETs biology; NETs in autoimmune diseases; NETs in immune response; NETs in development and progression of cancer diseases; NETs in immunothrombosis; degradation of NETs

(This special issue belongs to the Section Molecular Immunology)

Impact of Endogenic and Exogenic Oxidative Stress Triggers on Pregnant Woman, Fetus, and Child 2.0

edited by

Joško Osredkar

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2119 | Submission Open

Keywords: oxidative stress; angiogenesis; hypertension in pregnancy; preterm birth; metabolic syndrome; biomarkers; toxic agents; follicular fluid; amniotic fluid; cord blood

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Novel Insight into Microcirculation and Microvascular Diseases

edited by

Yu Wang

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2090 | Submission Open

Keywords: microcirculation; microangiopathy; vascular health; endothelial cells; resistance arteries; small vessels

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Expression of Signaling Genes in Cancer and Other Pathologies

edited by

Katarzyna Kośla

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2078 | Submission Open

Keywords: signaling pathways; gene expression; gene expression profile; cell signaling; cancer

(This special issue belongs to the Section Molecular Genetics and Genomics)

miRNAs in Carcinogenesis of Solid and Hematological Malignancies

edited by

Giuseppe Murdaca

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2075 | Submission Open

Keywords: miRNAs; hormones; telomerase; alarmins; cytokines; cancer; hematological malignancies

(This special issue belongs to the Section Molecular Oncology)

New Advances in Thyroid Cancer

edited by

Alessandro Antonelli

and

Yehuda Shoenfeld

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2055 | Submission Open

Keywords: thyroid cancer; thyroid autoimmunity; autoimmune thyroid disorders

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights of Main-Group and Transition Metal Compounds in Medicinal Chemistry

edited by

Diana V. Aleksanyan

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2011 | Submission Open

Keywords: main-group metal compounds; transition metal compounds; anticancer agents; antimicrobial agents; antifungal agents; antiviral agents; anti-inflammatory agents

(This special issue belongs to the Section Molecular Pharmacology)

Virus Entry Inhibitors

edited by

Asim Debnath

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1910 | Submission Open

Keywords: viral entry; entry inhibitors; small molecules; peptidomimetics; peptide-based; broadly neutralizing antibody (bNAb)

(This special issue belongs to the Section Molecular Informatics)

Leukemia: Present and Future

edited by

Carla Di Stefano

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1870 | Submission Open

Keywords: acute lymphoblastic leukemia (ALL); chronic lymphocytic leukemia (CLL); acute myelogenous leukemia (AML); chronic myelogenous leukemia (CML); non-Hodgkin Lymphoma in children; adolescents and young adults; Hodgkin lymphoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genomics: Infectious Disease and Host-Pathogen Interaction 3.0

edited by

Franklin W.N. Chow

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1860 | Submission Open

Keywords: infectious diseases; NGS; small RNA; host-pathogen interaction; pathogen detection; viruses; fungi; parasites; bacteria; evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Iron Dyshomeostasis

edited by

Carlo Marya Thomas Marobbio

and Sara Anjomani Virmouni

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1810 | Submission Open

Keywords: iron metabolism; iron dyshomeostasis; ferroptosis; oxidative stress; mitochondrial disease

(This special issue belongs to the Section Biochemistry)

Molecular Advances and Therapeutic Strategies in Renal Failure

edited by

Michele Andreucci

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1759 | Submission Open

Keywords: intracellular signaling; cell death; cell survival; gene; treatment; mortality; uremia; dialysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Structure, Function and Dynamics in Proteins: 2nd Edition

edited by

Luigi Russo

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1730 | Submission Open

Keywords: protein structure and dynamics; protein– protein and protein– DNA interactions; protein folding and misfolding; protein aggregation processes; intermediate/misfolded states; conformational equilibria; DNA and ligand recognition mechanisms; membrane receptors; enzyme dynamics; metal-binding proteins; intrinsically disordered proteins; cell signaling; phase separation mechanims; solution- and solid-state nmr; molecular dynamics simulations; time-resolved X-ray; NMR relaxation; in-/on-cell NMR; Cryo-EM; fluorescence polarization; surface plasmon resonance; static and dynamic light scattering; isothermal titration calorimetry; microscale thermophoresis; protein– fragment complementation assay; cross-linking; protein microarray

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Cancer Chemoprevention: Focus on Natural Product

edited by

Domenica Mangieri

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1728 | Submission Open

Keywords: natural compounds; phytochemicals; flavonoids; alkaloids; metastatic cascade; apoptosis; autophagy; cell cycle; drug resistance; oxidative stress; epithelial– mesenchymal transition; signaling pathways

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Gynecologic Cancer

edited by

Alicja Forma

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1724 | Submission Open

Keywords: ovarian cancer; uterine cancer; cervical cancer; vaginal cancer; vulvar cancer

(This special issue belongs to the Section Molecular Oncology)

Cellular and Molecular Mechanisms of Pathogenesis and Drug Effects in Tuberculosis

edited by

Selvakumar Subbian

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1722 | Submission Open

Keywords: tuberculosis; mycobacterium; vaccines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants

edited by

Katarzyna Hnatuszko-Konka

and

Izabela Grzegorczyk-Karolak

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1721 | Submission Open

Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Research for Legume Genomics, Genetics, and Breeding 2.0

edited by

Naoufal Lakhssassi

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1705 | Submission Open

Keywords: legumes; genomics; plant breeding; seed composition; gene function; biotic and abiotic stress; legume pathogen resistance/mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Anti-aging Treatment Development 2.0

edited by

Emanuele Marzetti

and

Anna Picca

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1704 | Submission Open

Keywords: healthspan; lifespan; hallmarks of aging; cellular quality control; inflammation; gut microbiota; geroscience; intercellular signaling; geroprotective interventions; chronic conditions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Antibacterial Materials

edited by

Elisa Boanini

and Gabriela Graziani

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1675 | Submission Open

Keywords: material functionalization; bioactive materials; antimicrobial; antibiofilm; metal coatings and nanoparticles; controlled release; biocompatibility

(This special issue belongs to the Section Materials Science)

Molecular Research on Gynecological Cancers: Ovarian Cancer, Endometrial Cancer, and Gestational Trophoblastic Disease

edited by Laura Mariuzzi,

Alessandro Mangogna

and

Maria Orsaria

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1671 | Submission Open

Keywords: ovarian cancer; endometrial cancer; gestational trophoblastic disease; prognostic factors; oncogenes; molecular genetics and genomics; DNA genotyping; cancer stem cells; epigenomics; signaling pathways; extracellular vesicles; tumour heterogeneity; tumour microenvironment; immune checkpoint inhibitors; new targets; molecular target

(This special issue belongs to the Section Molecular Oncology)

Understanding Sepsis: Pathophysiology, Diagnostics and Early Intervention

edited by Erika Bosio

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1658 | Submission Open

Keywords: biomarkers; inflammation; coagulation; endothelial dysfunction; sepsis; septic shock; organ failure; resuscitation; antibiotics; infection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Albumin in Tissue Regeneration and Repair

edited by Denes B. Horvathy

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1645 | Submission Open

Keywords: tissue regeneration; albumin; scaffolds; tissue engineering; albumin-based biomaterials; HAS; BSA

(This special issue belongs to the Section Molecular Biology)

Recent Research in Plant Abiotic Stress

edited by Viviana Maresca

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1638 | Submission Open

Keywords: abiotic stress; ROS; antioxidant enzymes; molecular responses; biochemical responses; physiological responses; stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms Related to Burns, Burn Wound Healing and Scarring: 3rd Edition

edited by

Lars-Peter Kamolz

, Marc Jeschke and

Sebastian P. Nischwitz

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1631 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism of pH Regulation: From Physiology to Pathology 2.0

edited by

Inyeong Choi

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1621 | Submission Open

Keywords: pH regulation; acid base transporter; acid base disturbance; acidosis; intracellular pH; NBC; NHE; cancer

(This special issue belongs to the Section Molecular Biology)

FTIR Miscrospectroscopy: Opportunities and Challenges

edited by Simona Sabbatini

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1607 | Submission Open

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Synthesis, Activity and Mechanism of Enzyme Inhibitors

edited by

Mariusz Mojzych

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1601 | Submission Open

Keywords: organic compounds; heterocycles; enzymes inhibition; mechanism of action; natural products; inhibitors; interaction with enzyme; kinetic studies of enzymatic reactions

(This special issue belongs to the Section Biochemistry)

Ion Channels as a Potential Target in Pharmaceutical Designs 2.0

edited by

Sheng-Nan Wu

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1599 | Submission Open

Keywords: ion currents; current kinetics; gating properties; voltage-dependent hysteresis; frequency-dependent regulation; small-molecule modulator

(This special issue belongs to the Section Molecular Biology)

The Occurrence, Evolution and Treatment of Glioblastoma 2.0

edited by

Antonella Mangraviti

submission deadline 30 Jun 2024 | 3 articles | Viewed by 1596 | Submission Open

Keywords: GBM; low-grade and high-grade; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; radiomics in brain tumors; re-surgery and re-radiation in GBMs; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

Role of Mutations and Polymorphisms in Various Diseases

edited by

Anna Cieślińska

and

Ewa Fiedorowicz

submission deadline 30 Jun 2024 | 3 articles | Viewed by 1578 | Submission Open

Keywords: nutrigenomics; polymorphism; SNPs; mutations; predisposition; correlation; diversity; deletion; insertion

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pathogenesis and Novel Therapeutic Approaches for Sarcomas

edited by Francisco Giner

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1569 | Submission Open

Keywords: soft tissue tumors; bone tumors; molecular biology; target therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Adipose Tissue Dynamics in Laminopathies

edited by Elisa Schena

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1555 | Submission Open

Keywords: lamin A/C; prelamin A; progerin; laminopathies; adipose tissue; adipocyte differentiation; lipodystrophy; lipoatrophy; HGPS; FPLD2; MADA; EDMD

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Applied Bioinorganic Chemistry

edited by

Christina N. Banti

and

Sotiris K Hadjikakou

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1555 | Submission Open

Keywords: applied bioinorganic chemistry in drug design and development; applied bioinorganic chemistry in catalysis; applied bioinorganic chemistry in materials science; applied bioinorganic chemistry in environmental science; applied bioinorganic chemistry in forensics; applied bioinorganic chemistry in imaging; applied bioinorganic chemistry in biotechnology; applied bioinorganic chemistry in agriculture; applied bioinorganic chemistry in energy conversion

(This special issue belongs to the Section Biochemistry)

Displaying special issue 301-350 on page 7 of 59.

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