Molecular Insights into Virus-Host Immune Interactions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 504
Special Issue Editor
Special Issue Information
Dear Colleagues,
Viral diseases represent a significant challenge to human health in the context of modern medicine, manifesting as a wide range of acute infections, chronic diseases, and virus-associated malignancies. The severity of pathogenesis is influenced by multiple factors, including viral and host characteristics. Immunocompromised patients (e.g., individuals living with HIV, post-transplant pharmacologic immunosuppression, or congenital diseases) are particularly vulnerable to opportunistic diseases, necessitating intensive interventions and distinct vaccination schedules. It is therefore imperative that we investigate the complex dynamics between viral pathogens and host immune responses in both healthy and immunocompromised individuals. This Special Issue will primarily focus on the mechanisms by which viruses evade immune recognition and counteract host defences, including interferon signalling and antibody responses. It is essential that we examine key molecular interactions, including the role of viral proteins in modulating host–cell functions, in order to gain insights into how SARS-CoV-2 and other viruses influence immune pathways. Furthermore, studies examining potential therapeutic strategies for the enhancement of immune responses and the targeting of viral components are urgently required. Authors are encouraged to consider insights that are applicable to other viral infections beyond SARS-CoV-2 and viral co-infections. This will contribute to a deeper understanding of virus–host interactions, which is essential in informing vaccine development and treatment approaches in the context of emerging infectious diseases. This Special Issue will provide a comprehensive and up-to-date overview of the vast and rapidly evolving field of virus–host interactions, through both original research and reviews, with a particular focus on the molecular insights that can inform public health strategies to combat viral threats.
Dr. Claudia Vanetti
Guest Editor
Manuscript Submission Information
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Keywords
- viral diseases
- virus–host interactions
- vaccination
- interferon signalling
- antibody responses
- viral proteins
- SARS-CoV-2
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