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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Pathophysiology and Immunology Related to SARS-CoV-2 Infection

edited by

Vito D’Agnano

submission deadline 30 May 2025 | 5 articles | Viewed by 7131 | Submission Open

Keywords: SARS-CoV-2; COVID-19; immunology; pathophysiology; immunopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Trends in Allergy and Autoimmunity: Pathogenesis, Biomarkers, and Treatment

edited by

Ilaria Mormile

submission deadline 30 May 2025 | 4 articles | Viewed by 7116 | Submission Open

Keywords: allergy; autoimmunity; autoimmune diseases; asthma; allergic rhinitis; urticaria; inflammation; molecular pathway; biomarkers; target therapy

(This special issue belongs to the Section Molecular Immunology)

Targeting Collagen-Related Therapy

edited by Fernando Revert

submission deadline 30 May 2025 | 3 articles | Viewed by 5934 | Submission Open

Keywords: collagen; extracellular matrix; molecular target; tissue engineering; drug deliver

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Properties and Applications of Nanoparticles and Nanomaterials: 2nd Edition

edited by Xiaogang Li

submission deadline 30 May 2025 | 5 articles | Viewed by 5511 | Submission Open

Keywords: nanostructures; nanoparticles; microstructure characterization; material design; evaluation of mechanical properties; applications of nanomaterials

(This special issue belongs to the Section Molecular Nanoscience)

Antifungal Drug Design, Synthesis and Molecular Mechanisms

edited by Zhibing Wu

submission deadline 30 May 2025 | 2 articles | Viewed by 3475 | Submission Open

Keywords: fungal diseases; antifungal compounds/agents; natural products; computer-aided drug design; synthetic compounds; mechanism of action; fungal disease management strategies

(This special issue belongs to the Section Molecular Informatics)

Recent Advances in Molecular Breeding for Drought and Salt Stress Tolerance in Crops: 2nd Edition

edited by

Zhaoshi Xu

submission deadline 30 May 2025 | 4 articles | Viewed by 3422 | Submission Open

Keywords: drought; salt; heat; cold; gene regulation; genomic research; multiomics; epigenetics; stress signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Hepatitis Viruses and Hepatocellular Carcinoma: Research, Treatment and Challenges

edited by

Boyan Grigorov

submission deadline 30 May 2025 | 1 articles | Viewed by 3177 | Submission Open

Keywords: HBV; HDV; HCV; virus replication and pathogenesis; antivirals; virus– cell interaction; vaccine development; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Immunology)

Seed Reserve Mobilization: Unveiling Cellular and Molecular Mechanisms

edited by

Raquel Iglesias Fernandez

submission deadline 30 May 2025 | 1 articles | Viewed by 3176 | Submission Open

Keywords: seed germination; reserve mobilization; vesicle trafficking; protein storage vacuoles (PSVs); oleosomes; seed storage tissues (endosperm; perisperm; cotyledon)

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Inflammatory Diseases of the Gut in Humans and Animals

edited by

Kostas A. Triantaphyllopoulos

submission deadline 30 May 2025 | 1 articles | Viewed by 2815 | Submission Open

Keywords: gene; epigenetic; biomarker; intestinal; gut; IBD; mycobacterium avium; Johne’ s disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Molecular Pathophysiology of Diabetes, Hypertension and Cardiovascular Diseases

edited by Alessandro Durante

submission deadline 30 May 2025 | 1 articles | Viewed by 2478 | Submission Open

Keywords: diabetes; hypertension; cardiology; cardiovascular diseases; coronary artery diseases; athero-sclerosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Musculoskeletal Involvement in Rare Diseases

edited by

Gianluigi Pasta

submission deadline 30 May 2025 | 1 articles | Viewed by 2139 | Submission Open

Keywords: rare diseases; molecular pathways; musculoskeletal system; bone involvement; joint degeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Dietary Compounds in Cancer Management

edited by

Maria Magdalena Mocanu

and

Alexandru Filippi

submission deadline 30 May 2025 | 1 articles | Viewed by 2057 | Submission Open

Keywords: dietary compounds; cancer prevention; cancer therapy; signaling pathways; heterogeneity; multidrug resistance; cancer stem cells; genetic modifications in cancer; cancer and inflammation; viral infection in cancer; tumor microenvironment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mitochondrial Function and Dynamics During Malignant Transformation

edited by Aleksandr Klepinin

submission deadline 30 May 2025 | 1 articles | Viewed by 1876 | Submission Open

Keywords: AMPK; phosphotransfer network; mitochondria; cancer metabolism; glycolysis; metabolic plasticity; cancer cell migration; molecular oncology; cancer treatment strategy

(This special issue belongs to the Section Biochemistry)

Bioinformatics and Machine Learning for Predicting Biological Processes

edited by Hao Lv

submission deadline 30 May 2025 | 1 articles | Viewed by 1705 | Submission Open

Keywords: bioinformatics; machine learning; multi-omics integration; gene regulation; biological processes; disease processes; data-driven discovery

(This special issue belongs to the Section Molecular Informatics)

Advanced Research of Mitochondria-Targeted Antioxidants

edited by

Pavel A. Nazarov

submission deadline 30 May 2025 | 1 articles | Viewed by 1678 | Submission Open

Keywords: antioxidants; mitochondria; biofilm; bacteria; yeast; aging; tumor; inflammation; bioenergetics; OXPHOS; metabolism

(This special issue belongs to the Section Molecular Biology)

Molecular Tools for the Development of Fermented Functional Foods Enriched with Bioactive Compounds

edited by Susana Langa,

Jose Antonio Curiel

and José María Landete

submission deadline 30 May 2025 | 1 articles | Viewed by 1436 | Submission Open

Keywords: molecular tools; fermentation; lactic acid bacteria; yeast; fungi; recombinant enzymes; probiotic; prebiotic; polyphenols; vitamins; food by-product valorization; bioactive compounds; antioxidant; anti-hypertensive; anti-carcinogenic; antimicrobial; anti-aging; food and beverages; GABA

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Therapeutic Potential of Natural Compounds: Insights into Mechanisms, Molecular Docking, and Biological Activities, 2nd Edition

edited by

Rafał Hałasa

and

Katarzyna Turecka

submission deadline 30 May 2025 | 3 articles | Viewed by 1299 | Submission Open

Keywords: natural compounds; synthetic derivatives of natural compounds; biological activity; mechanism of action; molecular docking; therapeutic potential; anticancer; antimicrobial; antiviral; anti-civilization diseases; antiobesity; antidiabetes; preventing the development of cardiovascular diseases; including myocardial infarction; hypertension and ischemic heart disease; food hypersensitivity; antiallergy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulatory Mechanisms of Development and Abiotic Stress Response by Transcriptional Regulators in Plants: 2nd Edition

edited by

Yong-Hwan Moon

submission deadline 30 May 2025 | 1 articles | Viewed by 1081 | Submission Open

Keywords: transcriptional regulator; transcription activation; transcription factor; transcription repression; plant development; abiotic stress response; epigenetic regulation; genome-wide analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Virus Infection and Infectious Diseases: Unraveling Mechanisms, Innovations and Therapeutic Strategies—Second Edition

edited by Jung-Hyun Lee

submission deadline 30 May 2025 | 2 articles | Viewed by 953 | Submission Open

Keywords: mechanism of virus infection; host immune responses; innovations in diagnostics and surveillance; therapeutic strategies; epidemiology and global health; data science for infectious disease; zoonotic transmission; virus evolution

(This special issue belongs to the Section Molecular Immunology)

Advances in Secondary Metabolites in Plants

edited by

Sławomir Dresler

submission deadline 30 May 2025 | 1 articles | Viewed by 808 | Submission Open

Keywords: specialized metabolites; biosynthesis pathways; pharmacological applications; medicinal plants; plant stress resistance; abiotic and biotic elicitors; chemometric analysis; plant biotechnology; therapeutic potential; plant signaling and communication

(This special issue belongs to the Section Molecular Plant Sciences)

Phytochemicals of Natural Products: Source, Analysis, and Bioactivities

edited by

Yu-Kuo Chen

, Chi-I Chang and Chi-Chien Lin

submission deadline 30 May 2025 | 1 articles | Viewed by 752 | Submission Open

Keywords: phytochemicals; bioactive compounds; natural products; bioactivities; purification; chemoprevention; chemotherapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Male Reproductive Physiology, Pathophysiology, and Contraception

edited by Gustavo G. Blanco

submission deadline 30 May 2025 | 1 articles | Viewed by 738 | Submission Open

Keywords: spermatogenesis; spermiogenesis; testis; epididymis; sperm function; sperm motility; sperm capacitation; acrosome reaction; male reproduction; male fertility; male infertility; male contraception

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Editing from Bench to Bedside and Back

edited by Daniel Rosenblum

submission deadline 30 May 2025 | Viewed by 643 | Submission Open

Keywords: gene editing; base editing; RNA therapeutics; CRISPR/Cas9; in vivo delivery; molecular medicine

(This special issue belongs to the Section Biochemistry)

Recent Research in Probiotic Yeasts: Molecular Aspects

edited by

Maurizio Ciani

and Francesca Comitini

submission deadline 30 May 2025 | 1 articles | Viewed by 622 | Submission Open

Keywords: probiotic yeasts; molecular mechanisms; mycocins active; compounds; functional compounds

(This special issue belongs to the Section Molecular Microbiology)

Long Non-coding RNAs in Plants

edited by

Changning Liu

submission deadline 30 May 2025 | Viewed by 541 | Submission Open

Keywords: long noncoding RNAs; plants; gene regulation; development; stress responses

(This special issue belongs to the Section Molecular Plant Sciences)

Cotton Molecular Genomics and Genetics (Third Edition)

edited by

Jie Sun

submission deadline 30 May 2025 | 1 articles | Viewed by 523 | Submission Open

Keywords: cotton; biotic or abiotic stress; disease resistance; fiber yield and quality; gene editing; gene identification and function validation; genome-wide association study; QTL identification

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms in Mitochondria-Targeted Drug Delivery System

edited by

Maria Manuel Oliveira

and

Francisco Peixoto

submission deadline 30 May 2025 | Viewed by 483 | Submission Open

Keywords: mitochondria; mitochondrial diseases; nanoformulations; therapeutic agents; drug release; precision medicine

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Molecular Biology on Mycobacteria: 2nd Edition

edited by

Rita Macedo

submission deadline 30 May 2025 | 1 articles | Viewed by 483 | Submission Open

Keywords: genus Mycobacterium; non-tuberculous mycobacteria; Mycobacterium tuberculosis; Mycobacterium leprae; molecular diagnosis; molecular surveillance methodologies; molecular resistance prediction

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights and Regulation Mechanisms of Tea Quality

edited by

Xujun Zhu

submission deadline 30 May 2025 | 1 articles | Viewed by 437 | Submission Open

Keywords: molecular ecology; spectroscopic techniques; tea quality; tea plant growth

(This special issue belongs to the Section Molecular Plant Sciences)

Gut Microbiota and Nutrition in Human Health (2nd Edition)

edited by

Sunmin Park

submission deadline 30 May 2025 | Viewed by 431 | Submission Open

Keywords: microbiome; gut; brain; obesity; diabetes; inflammation; liver; nutrition; probiotic; prebiotic

(This special issue belongs to the Section Molecular Microbiology)

Spectral Control of Stress Response in Plants

edited by

Gábor Kocsy

and Zsolt Gulyás

submission deadline 30 May 2025 | Viewed by 406 | Submission Open

Keywords: spectral control; stress response; light spectrum; photoreceptor; reactive oxygen; plant hormone; antioxidant; plant growth and development

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Advances in Plant Abiotic Stress

edited by

Kincső Decsi

submission deadline 30 May 2025 | 1 articles | Viewed by 343 | Submission Open

Keywords: abiotic stress factors; priming effects; defense responses; biochemical pathway analyses; transcriptomics; plant conditioners; next-generation sequencing; genome-wide analyses

(This special issue belongs to the Section Molecular Plant Sciences)

Drug Delivery Systems in Veterinary Medicine: Innovations and Applications

edited by

Hualin Fu

submission deadline 30 May 2025 | Viewed by 301 | Submission Open

Keywords: design of novel veterinary drug delivery systems; methods of preparing a veterinary drug delivery system; mechanisms of action of veterinary drug delivery systems; impact of veterinary drug delivery systems on in vivo processes of veterinary drugs; clinical evaluation of veterinary drug delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Immunological Biomarkers in Cervical Cancer

edited by Janaina Cristiana de Oliveira Crispim and

Ricardo Ney Oliveira Cobucci

submission deadline 30 May 2025 | Viewed by 294 | Submission Open

Keywords: cervical cancer; molecular biomarkers; immunological biomarkers; human papillomavirus (HPV); tumor microenvironment; immune responses; immunotherapy; diagnostic biomarkers; prognostic biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Insights into the Molecular Mechanisms of the UPR and Cell Stress

edited by

Quang Duy Trinh

submission deadline 30 May 2025 | Viewed by 272 | Submission Open

Keywords: unfolded protein response; ER stress; oxidative stress; mitochondrial dysfunction; cell stress; stress response; UPR signaling pathway; immunity; inflammation; infection

(This special issue belongs to the Section Molecular Biology)

Adipose Tissue and Adipose Tissue-Derived Stem Cells in Multidisciplinary Research

edited by Oliver Felthaus

submission deadline 30 May 2025 | Viewed by 262 | Submission Open

Keywords: adipose tissue; adipose-derived stem cells; regenerative medicine; tissue engineering

(This special issue belongs to the Section Molecular Biology)

New Perspectives in 3D Bioprinting

edited by Pamela Mozetic and

Alessio Bucciarelli

submission deadline 30 May 2025 | Viewed by 229 | Submission Open

Keywords: 3D bioprinting; regenerative medicine; pluripotent stem cells; disease modeling; precision medicine

(This special issue belongs to the Section Materials Science)

Thrombo-Inflammatory Signaling and Complications in Autoimmune Disorders

edited by

Alexandros Tsoupras

submission deadline 30 May 2025 | Viewed by 213 | Submission Open

Keywords: inflammation; thrombosis; platelets; coagulation; autoimmune disorders; rheumatoid arthritis; systematic erythematosus lupus; antiphospholipid syndrome; thrombo-inflammation; antithrombotic; antiplatelet

(This special issue belongs to the Section Molecular Immunology)

Sjogren's Disease: Multidimensional Perspectives on Pathogenesis, Clinical Manifestations, and Therapeutic Advancements

edited by

Xiang Lin

submission deadline 30 May 2025 | Viewed by 213 | Submission Open

Keywords: Sjö gren's disease; diagnosis; therapeutics; bioinformatics; pre-clinical; cytokine; lymphocytes; autoantibodies; exocrine glands

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Malaria: Molecular and Biochemical Perspectives

edited by

Pedro Eduardo Ferreira

submission deadline 30 May 2025 | Viewed by 203 | Submission Open

Keywords: malaria; vectors; therapies; resistance; cellular mechanisms

(This special issue belongs to the Section Molecular Microbiology)

Rapeseed: Genetic Breeding, Key Trait Mining and Genome

edited by Hongbo Chao

submission deadline 30 May 2025 | Viewed by 198 | Submission Open

Keywords: rapeseed (Brassica napus L.); genetic breeding; genomic improvement; molecular markers; genome-wide association studies (GWAS); multi-omics integration; CRISPR gene editing; marker-assisted selection (MAS); stress resistance traits; yield and oil content improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Cardiomyopathy: From Molecular Pathology to Treatment

edited by

Andrea Sonaglioni

and

Gian Luigi Nicolosi

submission deadline 30 May 2025 | Viewed by 197 | Submission Open

Keywords: obesity; myocardial fibrosis; subclinical myocardial dysfunction; fibrotic remodeling; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biocomposite Hydrogels for Biomedical Applications

edited by

Leonard Ionut Atanase

submission deadline 30 May 2025 | 1 articles | Viewed by 195 | Submission Open

Keywords: hydrogels; biocomposite; micro/nanoparticles; electrospun fibers; inorganic particles; tissue engineering; drug delivery; 3D printing

(This special issue belongs to the Section Materials Science)

Protein Modification: New Insights

edited by

Yeou-Guang Tsay

submission deadline 30 May 2025 | Viewed by 185 | Submission Open

Keywords: post-translational modifications (PTMs); side chain modifications; backbone modifications; analytical protein chemistry; mass spectrometry

(This special issue belongs to the Section Biochemistry)

Exploring the Genetics in Rare Diseases: A Genomic Odyssey

edited by

Klaus Brusgaard

submission deadline 30 May 2025 | Viewed by 169 | Submission Open

Keywords: novel discoveries in rare disorders; polygenic risk scores; mosaicism; protein interaction; tools utilized to engineer DNA; somatic variants; patient advocacy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Mechanisms of Bitter Taste Receptors in Immune Disease

edited by

Luigia Grazia Fresu

and

Maria Talmon

submission deadline 30 May 2025 | Viewed by 163 | Submission Open

Keywords: bitter taste receptors; TAS2Rs; immune disease; immunity response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Markers and Genetic Diversity in Plants

edited by Eugenija Kupčinskienė

submission deadline 30 May 2025 | Viewed by 162 | Submission Open

Keywords: plant populations; genetic diversity; molecular diversity; invasion; invasive alien species; pollution; climate change; habitat; conservation; endangered and rare species; DNA markers; molecular markers; sequencing

(This special issue belongs to the Section Molecular Plant Sciences)

Amyotrophic Lateral Sclerosis (ALS): Pathogenesis and Treatments

edited by

Monica Consonni

and

Stefania Marcuzzo

submission deadline 30 May 2025 | Viewed by 157 | Submission Open

Keywords: amyotrophic lateral sclerosis; therapeutic applications; extracellular-vesicles; gene variants; RNA metabolism; mitochondrial dysfunction; oxidative stress; neuroinflammation; protein misfolding; muscle impariment

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Chronic Liver Disease and Liver Failure

edited by Paolo Gallo

submission deadline 30 May 2025 | Viewed by 157 | Submission Open

Keywords: cirrhosis; portal hypertension; liver failure; advanced chronic liver disease; sarcopenia and malnutrition; ascites; medical treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Topics in Polymer Crystallization

edited by Lei Zhang

submission deadline 30 May 2025 | Viewed by 152 | Submission Open

Keywords: polymer crystal; nucleation and growth; crystallization under extreme conditions; characterization of crystal structure

(This special issue belongs to the Section Macromolecules)

Displaying special issue 351-400 on page 8 of 68.

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