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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bone Biomaterials Research and 3D Spheroid Culture Systems in Osteogenesis

edited by

Chawon Yun

submission deadline 30 Jul 2025 | 1 articles | Viewed by 4060 | Submission Open

Keywords: osteogenic differentiation; 3D culture; bone regeneration; toxicological and pharmacological assessment; bone homeostasis; bone materials

(This special issue belongs to the Section Materials Science)

Pathogenicity and Antibiotic Resistance of Helicobacter pylori

edited by

Paweł Krzyżek

submission deadline 30 Jul 2025 | 2 articles | Viewed by 3700 | Submission Open

Keywords: Helicobacter pylori; antibiotic resistance; antibiotic tolerance; point mutations; efflux pumps; biofilm formation; coccoid forms; membrane vesicles; virulence factors

(This special issue belongs to the Section Molecular Microbiology)

Protein Methyltransferases in Human Health and Diseases

edited by

Byron Baron

submission deadline 30 Jul 2025 | 1 articles | Viewed by 3625 | Submission Open

Keywords: lysine and arginine methylation; mass spectrometry; PTM cross talk; functional proteomics; cancer; neurological disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Roles for Serotonin in Regulating Metabolism

edited by

Giuseppe Bruschetta

and

Patrizia Licata

submission deadline 30 Jul 2025 | 2 articles | Viewed by 3095 | Submission Open

Keywords: serotonin; cortisol; phospholipids; glycosaminoglycans; oxidative stress; veterinary anesthesia and analgesia

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Antiviral Drugs Discovery

edited by

Dongwei Kang

submission deadline 30 Jul 2025 | 2 articles | Viewed by 2897 | Submission Open

Keywords: antiviral agents; organic synthesis and medicinal chemistry; biological activity; drug design and computational chemistry; drug discovery and development

(This special issue belongs to the Section Molecular Pharmacology)

The Role of Cytokines in Health and Diseases

edited by Hung-Jen Liu

submission deadline 30 Jul 2025 | 5 articles | Viewed by 2891 | Submission Open

Keywords: cytokines; immune regulation; disease management; signaling pathways; translational research; clinical applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism and Treatment of Allergic Asthma

edited by

Francesco Menzella

and Marcello Cottini

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2881 | Submission Open

Keywords: allergic asthma; epithelial barrier damage; protease allergen; type 2 inflammation

(This special issue belongs to the Section Molecular Immunology)

The Role of Glycans in Immune Regulation

edited by Senlian Hong

submission deadline 30 Jul 2025 | 2 articles | Viewed by 2661 | Submission Open

Keywords: glycoimmunology; glycotherapy; vaccines; glycan synthesis; immune tolerance

(This special issue belongs to the Section Molecular Immunology)

Current Insights into Nucleic Acids

edited by

David Stephen Pisetsky

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2410 | Submission Open

Keywords: nucleic acids; DNA; RNA; genome; gene function; gene regulation; gene structure

(This special issue belongs to the Section Molecular Genetics and Genomics)

Plant–Microbe Interactions: 2nd Edition

edited by Jian Jin

submission deadline 30 Jul 2025 | 4 articles | Viewed by 2337 | Submission Open

Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances Related to Bone Regeneration

edited by

Gianluigi Pasta

and

Virginie Sottile

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2225 | Submission Open

Keywords: bone regeneration; bone extracellular matrix; regenerative medicine; biomaterials

(This special issue belongs to the Section Molecular Biology)

Dietary Components in the Brain–Gut Axis: Exploring Nutrigenetic and Microbiome Interactions

edited by

Piotr Dobrowolski

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2143 | Submission Open

Keywords: dietary components; carbohydrates; proteins; fats; fatty acids; vitamins; minerals; brain– gut axis; nutrigenetics; microbiome interactions; neurodegenerative disorders; metabolic pathways

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Food-Derived Bioactive Peptides

edited by

Fidel Toldrá

and

Leticia Mora

submission deadline 30 Jul 2025 | 3 articles | Viewed by 2142 | Submission Open

Keywords: peptides identification; peptides characterization; functional foods; biological activity; peptidomics; proteomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Diagnostic and Treatment Methods in Socially Significant Diseases in Urology

edited by

Elenko Popov

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1985 | Submission Open

Keywords: prostate cancer; bladder cancer; renal-cell cancer; risk stratification; urolithiasis; chronic UTIs; BPH; clinical decision-making

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Structural Research Advances in Model Plants (Second Edition)

edited by

Ioannis-Dimosthenis Adamakis

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1885 | Submission Open

Keywords: A. thaliana; plant biology; model organisms; plant models; non-model plant models

(This special issue belongs to the Section Molecular Plant Sciences)

Focus on Gastrointestinal Diseases: Inflammation, 3rd Edition

edited by

Marcello Candelli

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1729 | Submission Open

Keywords: signal transduction; receptor signaling; infection and inflammation; protein interaction; tumor biology; growth factors; cytokines; cell death and differentiation; inflammation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Design, Synthesis and Applications of Peptide Nucleic Acid

edited by

Maria Moccia

, Concetta Avitabile and

Annalisa Masi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1722 | Submission Open

Keywords: PNA; nucleic acid analog; molecular design; synthesis; delivery system; therapeutics; diagnostic

(This special issue belongs to the Section Molecular Biology)

The Role of Autoimmunity in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

edited by Yang Mao-Draayer

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1656 | Submission Open

Keywords: multiple sclerosis (MS); neuromyelitis optica spectrum disorder (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); immunomodulatory; neuroprotection; neuroregeneration; biomarker; imaging

(This special issue belongs to the Section Molecular Neurobiology)

Autoimmune Diseases: From Pathogenesis to Treatment and Prognostic Markers

edited by Alessandra Bettiol

submission deadline 30 Jul 2025 | 3 articles | Viewed by 1587 | Submission Open

Keywords: autoimmune diseases; inflammation; immunity; pathogenesis; immunosuppressants; biologics; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases: 3rd Edition

edited by

Kyriacos N. Felekkis

and

Christos Papaneophytou

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1234 | Submission Open

Keywords: miRNA; gene expression regulation; diagnosis; prognosis; therapy; biomarkers

(This special issue belongs to the Section Biochemistry)

New Insights in Antibody Therapy

edited by

Loredana Frasca

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1207 | Submission Open

Keywords: biological therapy; antibody therapy; non-communicable diseases; infectious diseases; chronic disease

(This special issue belongs to the Section Molecular Immunology)

Crop Stress Biology and Molecular Breeding: 5th Edition

edited by

Youxiong Que

submission deadline 30 Jul 2025 | 3 articles | Viewed by 1182 | Submission Open

Keywords: biotic and abiotic stress; variety improvement; crop stress biology; molecular breeding; biological basis; signal transduction pathway; agronomic traits; excellent germplasm

(This special issue belongs to the Section Molecular Plant Sciences)

The Molecular Network, Key Biomarkers, and Therapeutic Targets in Colorectal Cancer

edited by

Katharina M. Robertson

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1175 | Submission Open

Keywords: inflammation; metabolism; tumor-associated macrophages; tumor microenvironment; early-onset colorectal cancer; colorectal neoplasms; obesity; immunotherapy; epigenetics; cytokines; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1143 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone– immune interface

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular Mechanisms of Bacterial Resistance and Antibiotic Therapy

edited by

Xinyi Yang

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1112 | Submission Open

Keywords: bacterial resistance; antibiotics; antimicrobials; “ superbugs” ; clinical strains; laboratory induced-bacteria; antimicrobial peptides; antimicrobial combinations; hybrid antibiotics; repurposing drugs; anti-virulence agents; immune modulators; toxin neutralizers

(This special issue belongs to the Section Molecular Microbiology)

Cirrhosis: From Molecular Mechanisms to Therapeutic Strategies

edited by

Hongqun Liu

submission deadline 30 Jul 2025 | 2 articles | Viewed by 832 | Submission Open

Keywords: liver; fibrogenesis; cirrhosis; portal hypertension; complications; molecular mechanisms; pathway; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Radiation Resistance in Extremophile Bacteria: Unraveling the Molecular Mysteries

edited by

Sathiyaraj Srinivasan

submission deadline 30 Jul 2025 | 1 articles | Viewed by 804 | Submission Open

Keywords: extremophiles; radiation resistance; genome analysis; RNAseq; proteome studies; comparative analysis; molecular mechanisms; genetic adaptation; metabolic shifts; evolutionary insights; eukaryotic resistance

(This special issue belongs to the Section Molecular Microbiology)

Parkinson’s Disease and Related Diseases: Mechanisms, Genetic Factors and Treatments

edited by

Stergios Boussios

submission deadline 30 Jul 2025 | 2 articles | Viewed by 794 | Submission Open

Keywords: Parkinson’ s disease; neurodegenerative disorders; α -synuclein aggregation; neuroinflammation; gene therapy; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Obesity: From Pathogenesis to Therapeutic Targets

edited by Omar Al Massadi, Mar Quiñones and

Luisa Maria Seoane

submission deadline 30 Jul 2025 | 1 articles | Viewed by 754 | Submission Open

Keywords: obesity; energy balance; type 2 diabetes; liver disease; adipose tissue; brain

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Macro- and Micronutrients in Health and Diseases

edited by

Karolina Orywal

and Mariusz Gryko

submission deadline 30 Jul 2025 | 1 articles | Viewed by 738 | Submission Open

Keywords: macronutrients; micronutrients; vitamins; macrominerals; trace elements; cancer; obesity; cardiovascular diseases; diabetes; osteoporosis; immune disorders; neurodegenerative diseases

(This special issue belongs to the Section Molecular Biology)

Protein Kinase in Disease, 2nd Edition

edited by

Manae Suzuki Kurokawa

submission deadline 30 Jul 2025 | 1 articles | Viewed by 702 | Submission Open

Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Plant-Derived Products in the Service of Immune Regulation

edited by

Lyuba Dineva Miteva

submission deadline 30 Jul 2025 | 1 articles | Viewed by 677 | Submission Open

Keywords: plant bioactive compound; inflammation; immunity; cytokine; chronic disease

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of Nanomaterial-Mediated Immune Modulation

edited by

Ivan Kempson

submission deadline 30 Jul 2025 | Viewed by 659 | Submission Open

Keywords: nanomaterial; immune modulation; immunological responses

(This special issue belongs to the Section Molecular Nanoscience)

Green Chemical Pesticide Design, Synthesis and Evaluation

edited by Ranfeng Sun

submission deadline 30 Jul 2025 | 1 articles | Viewed by 638 | Submission Open

Keywords: green pesticides; natural products; action mechanism of pesticides; synthesis

(This special issue belongs to the Section Biochemistry)

Cerebrovascular Diseases: Mediators of the Capillary No-Reflow Phenomenon After Acute Ischemic Stroke

edited by Ákos Menyhárt

submission deadline 30 Jul 2025 | 1 articles | Viewed by 637 | Submission Open

Keywords: capillary; acute ischemic stroke; cerebrovascular; no-reflow

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hyperelastic Structures

edited by

Hossein Bakhshi Khaniki

and

Mergen Ghayesh

submission deadline 30 Jul 2025 | Viewed by 629 | Submission Open

Keywords: hyperelastic structures; biological properties; molecular properties; nonlinear elasticity; soft structures; material modeling

(This special issue belongs to the Section Materials Science)

The Role of Bioactive Compounds in Human Health and Disease: 3rd Edition

edited by

Guan-Jhong Huang

submission deadline 30 Jul 2025 | 1 articles | Viewed by 571 | Submission Open

Keywords: cancer; inflammation; cardiovascular diseases; plants; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Dynamics Simulations of Protein Structures

edited by Alfonso Trezza

submission deadline 30 Jul 2025 | 1 articles | Viewed by 556 | Submission Open

Keywords: molecular dynamics simulations; protein structure analysis; computational methods in structural biology; bioinformatics and drug discovery; protein– ligand interactions

(This special issue belongs to the Section Molecular Biophysics)

Molecular Interactions and Advanced Computational Methods for Biomolecular Systems

edited by

Amar Singh

submission deadline 30 Jul 2025 | 1 articles | Viewed by 549 | Submission Open

Keywords: molecular interactions; biological systems; computational biology; protein– protein interactions; protein docking; bioinformatics; structural modeling; multiscale modeling techniques

(This special issue belongs to the Section Molecular Biophysics)

Energy Metabolism and Obesity: 2nd Edition

edited by

Po-Shiuan Hsieh

submission deadline 30 Jul 2025 | Viewed by 514 | Submission Open

Keywords: energy metabolism; obesity; insulin resistance; glucose and lipid metabolism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Drugs Targeting Cancer Signaling Pathways: Dissecting Mechanisms to Unlock New Therapeutic Targets

edited by Souleymane Abdoul-Azize

submission deadline 30 Jul 2025 | 1 articles | Viewed by 497 | Submission Open

Keywords: small-molecule drugs; signal transduction; therapeutic targets; therapeutic resistance; oncogenic signaling; novel biomarkers; cancer therapy; cancer signaling pathways; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Diabetic Retinopathy—Innovation in Diagnosis and Treatment

edited by

Peter Koulen

submission deadline 30 Jul 2025 | Viewed by 486 | Submission Open

Keywords: diabetes mellitus; diabetic macular edema; diagnostics; drug development; neovascularization; neurodegeneration; neuroprotection; retina; therapeutics; vascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Linking Obesity to Atherosclerosis Pathogenesis

edited by

Weibin Shi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 481 | Submission Open

Keywords: obesity; overweight; atherosclerosis; coronary artery disease; obesity paradox; body mass index; visceral fat

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms in Kidney Disease

edited by

Tzong-Shyuan Lee

submission deadline 30 Jul 2025 | 1 articles | Viewed by 473 | Submission Open

Keywords: kidney disease; inflammation; redox; senescence; cell death; fibrosis; signaling pathway; uremic syndrome; cardiorenal syndrome; gut– kidney axis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Applications of Gold Nanoparticles in Cancer Theranostics

edited by John Chetley Ford and

Junwei Shi

submission deadline 30 Jul 2025 | Viewed by 379 | Submission Open

Keywords: gold nanoparticles (AuNPs); multifunctional nanoplatform; targeted cancer therapy; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

Neurological Disorders: From Molecular Mechanisms to Nanomedicine

edited by

Aruna Sharma

submission deadline 30 Jul 2025 | Viewed by 350 | Submission Open

Keywords: stroke; brain and spinal cord trauma; Alzheimer’ s disease; Parkinson’ s disease; nanodrug formulation; stem cells; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Sepsis and Septic Shock: From Molecular Mechanisms to Novel Therapies—2nd Edition

edited by

Markus A. Weigand

and Michael Adamzik

submission deadline 30 Jul 2025 | Viewed by 342 | Submission Open

Keywords: sepsis; septic shock; mechanistic insight; epigenetics; immunometabolism; biomarkers; therapy approach; stratification; precision diagnostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology and Diagnosis on Biliary and Pancreatic Cancers

edited by Francesco Vasuri and Luca Saragoni

submission deadline 30 Jul 2025 | Viewed by 276 | Submission Open

Keywords: biliary cancer; pancreatic cancer; histological diagnoses; cytological diagnoses; chromosome aneuploidy; specific genetic mutations

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms Study of Functional Foods and Nutrients in Human Health Interventions

edited by

Rui Jiao

submission deadline 30 Jul 2025 | 1 articles | Viewed by 208 | Submission Open

Keywords: functional foods; molecular mechanisms; nutrient bioavailability; chronic disease prevention; health interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Protein Design and Engineering in Biochemistry

edited by Om Prakash Narayan

submission deadline 30 Jul 2025 | Viewed by 203 | Submission Open

Keywords: protein engineering; molecular biology; biochemical tools; computational protein design; directed evolution; CRISPR/Cas9; synthetic biology; biomaterials; protein therapeutics; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 351-400 on page 8 of 69.

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