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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 20 Aug 2025 | Viewed by 178 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies of Hematologic Malignancies

edited by

Myunggon Ko

submission deadline 20 Aug 2025 | Viewed by 99 | Submission Open

Keywords: hematologic malignancies; molecular mechanisms; genetic and epigenetic aberrations; molecular diagnosis; targeted therapy and biomarkers

(This special issue belongs to the Section Molecular Oncology)

Nrf1/2/3 and Other Antioxidant Transcription Factors in Health and Disease

edited by

Eleonora Stanca

submission deadline 20 Aug 2025 | Viewed by 82 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Aug 2025 | Viewed by 73 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Aug 2025 | Viewed by 67 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Development and Applications of Biodegradable and Bioactive Materials

edited by

Mercedes Ana Peltzer

submission deadline 20 Aug 2025 | Viewed by 48 | Submission Open

Keywords: biopolymers; bioplastics; sustainability; food packaging; medicine and cosmetic; bioactive compounds; wound healing; active and intelligent packaging

(This special issue belongs to the Section Materials Science)

Molecular Studies of Endometriosis and Associated Diseases

edited by Sarah J Holdsworth-Carson

submission deadline 21 Aug 2025 | 4 articles | Viewed by 5019 | Submission Open

Keywords: adenomyosis; autoimmune diseases; cardiometabolic conditions; endometriosis; fatigue; heavy menstrual bleeding; irritable bowel syndrome; migraine; painful bladder syndrome; pelvic floor muscle dysfunction; pelvic inflammatory disease; pelvic pain; peritoneal adhesions; polycystic ovarian syndrome; pregnancy complications; ovarian cancer; uterine fibroids

(This special issue belongs to the Section Molecular Biology)

Advances in Cardiometabolic Phenotypes of Pediatric Obesity

edited by Simona Georgiana Popa

submission deadline 22 Aug 2025 | Viewed by 740 | Submission Open

Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Endothelial Cells in Cancer: Molecular Advance

edited by Dae Joong Kim

submission deadline 22 Aug 2025 | Viewed by 129 | Submission Open

Keywords: tumor angiogenesis; metastasis; VEGFs; FGFs; Ang2; immune surveillance; antigen presentation; EC adhesion molecules; LYVE-1; lymphatic vessel; antigen-presenting cell; lymphocytes; high endothelial venule

(This special issue belongs to the Section Biochemistry)

New Insights into Bioactive Peptides: Design, Synthesis, Structure-Activity Relationship (2nd Edition)

edited by

Marilisa Leone

and

Flavia Anna Mercurio

submission deadline 25 Aug 2025 | 6 articles | Viewed by 7439 | Submission Open

Keywords: peptides; protein-peptide interactions; PPI inhibition and modulation; peptide drugs; peptidomimetics; cyclic peptides; stapled peptides; diagnostic peptides; peptides for drug delivery; multidisciplinary approaches TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biological Research on Plant Bioactive Compounds

edited by

Adriana Trifan

and

Simon Vlad Luca

submission deadline 25 Aug 2025 | 7 articles | Viewed by 6615 | Submission Open

Keywords: plant bioactive compounds; extraction and analysis of plant bioactive compounds; bioactivity and pharmacokinetics of plant compounds; natural products and modern diseases; plant bioactive compounds and by-products; discovery and development of natural plant drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Isolation and Biological Activities of Natural Products: Focus on Molecular Advance

edited by Pedro Ferreira and

Patricia Reboredo-Rodríguez

submission deadline 25 Aug 2025 | 1 articles | Viewed by 810 | Submission Open

Keywords: natural products; sustainable isolation; biological activities; therapeutic potential; structure-activity relationships; omics technologies; bioavailability; functional foods; green chemistry; molecular docking

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Epilepsy: From Molecular Physiology to Pathology

edited by Paolo Mainardi

submission deadline 25 Aug 2025 | Viewed by 439 | Submission Open

Keywords: epilepsy; molecular pathology; disease; therapeutic strategies; celluar advance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Terpenes: Molecular Pharmaceutics and Biotechnology

edited by Lídia Pinheiro and

Célia Faustino

submission deadline 25 Aug 2025 | Viewed by 401 | Submission Open

Keywords: terpenes; antimicrobial; anticancer; anti-inflammatory; drug discovery; drug delivery; flavours; fragrances; biofuels; biocatalysis; bioremediation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Obesity: Different Perspectives Based on Molecular Physiology and Pathology

edited by Hector I. Rocha-Gonzalez

submission deadline 25 Aug 2025 | Viewed by 105 | Submission Open

Keywords: obesity; rational management; perspectives; new ideas; pharmacology; lifestyle modification; molecular advances

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Degradable Polymers: Synthesis, Applications, and Environmental Impact

edited by Ce Sun and

Haiyang Gao

submission deadline 25 Aug 2025 | Viewed by 104 | Submission Open

Keywords: degradable polymer; synthesis; degradation mechanisms; sustainability

(This special issue belongs to the Section Macromolecules)

Molecular Diagnosis and Treatments of Diabetes Mellitus: 2nd Edition

edited by

Mihail Virgil Boldeanu

submission deadline 25 Aug 2025 | Viewed by 89 | Submission Open

Keywords: metabolic disorders; diabetes mellitus; inflammation; neurotransmitter; inflammatory biomarkers; molecular target; molecular diagnostics; therapeutics; insulin resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

CRISPR/Cas Systems and Genome Editing—3rd Edition

edited by

Dmitry Karpov

submission deadline 25 Aug 2025 | Viewed by 77 | Submission Open

Keywords: CRISPR/Cas; bacterial argonauts; transcription regulation; genome editing; genome editing tools

(This special issue belongs to the Section Molecular Genetics and Genomics)

Metabolic Regulators of Bone Health

edited by

Akkouch Adil

submission deadline 25 Aug 2025 | Viewed by 72 | Submission Open

Keywords: bone; osteoporosis; diabetes; obesity; glucose; insulin; lipids; estrogen; microRNA; osteoblasts

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in the Role of Retinoic Acid-Regulated Genes in Cancer Biology

edited by Fuming Tsai

submission deadline 25 Aug 2025 | Viewed by 58 | Submission Open

Keywords: retinoic acid; retinoic acid receptors; retinoic x receptors; tumorigenesis; metastasis; tumor microenvironment; molecular pathways

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Dyslipidemia

edited by

Aleksandra Zeljkovic

and

Jelena Vekić

submission deadline 25 Aug 2025 | Viewed by 56 | Submission Open

Keywords: dyslipidemia; chronic non-communicable diseases; dysregulation of lipid homeostasis; genetic and epigenetic regulation; lipidomics in personalized medicine; lipid biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Lung Cancer: From Genetic Landscape to Treatment

edited by Rossella Bruno

submission deadline 26 Aug 2025 | 1 articles | Viewed by 1547 | Submission Open

Keywords: lung cancer; precision medicine; predictive biomarkers; resistance mechanisms; targeted therapy; immunotherapy; molecular tests; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Recent Research on Optoelectronic Materials

edited by

Meysam Tayebi

submission deadline 28 Aug 2025 | Viewed by 171 | Submission Open

Keywords: photoelectrochemistry; optoelectronic materials; perovskite materials; semiconductor interfaces; molecular-level catalysis; solar fuel conversion; nanostructured materials; light-harvesting systems

(This special issue belongs to the Section Materials Science)

Mechanistic Insights into Pharmacological and Non-Pharmacological Pain Therapies: From Cellular Responses to Therapy Outcomes

edited by

Sungtae Koo

submission deadline 28 Aug 2025 | Viewed by 145 | Submission Open

Keywords: neuromodulation; neural plasticity; glial activation; endogenous pain modulation; neuroinflammation; therapeutic mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Molecular Pharmacology of Neurological Diseases

edited by

Chian Ju Jong

submission deadline 28 Aug 2025 | Viewed by 96 | Submission Open

Keywords: neurological diseases; neurodevelopmental disorders; neurodegenerative diseases; therapeutic agents; drug discovery; molecular pharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Biology of Plant Disease Resistance

edited by Heewan Kang

submission deadline 28 Aug 2025 | Viewed by 71 | Submission Open

Keywords: Bacillus subtilis; antifungal activity; amino acids; defense genes; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

The Neuro and Immune Mechanisms Behind Cannabinoids Effects

edited by

Babak Baban

submission deadline 28 Aug 2025 | Viewed by 61 | Submission Open

Keywords: cannabinoids; neuroinflammation; endocannabinoid system (ECS); non-cannabinoid receptors; immune modulation; synaptic plasticity

(This special issue belongs to the Section Biochemistry)

Molecular Biomarkers for Assessing Marine Ecosystem Health

edited by

Maria Costantini

Valerio Zupo

and

Roberta Esposito

submission deadline 28 Aug 2025 | Viewed by 36 | Submission Open

Keywords: biodiversity; biomarkers; biomonitoring; marine organisms; pollution; metals; microplastics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Immune Regulation During Pregnancy

edited by Sabrina Marie Scroggins

submission deadline 28 Aug 2025 | Viewed by 31 | Submission Open

Keywords: maternal– fetal immunology; multiomics in pregnancy; in utero inflammation; therapeutics; placental biology; neurodevelopment; gestational disorders; epigenetics; microbiome

(This special issue belongs to the Section Molecular Immunology)

Anti-Inflammatory and Anti-Oxidant Effects of Extracts from Plants

edited by

Sheila Leone

and

Lucia Recinella

submission deadline 29 Aug 2025 | 1 articles | Viewed by 354 | Submission Open

Keywords: oxidative stress; inflammation; herbal extracts

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Application and Formulation of Therapeutic Natural Deep Eutectic Solvents

edited by

Kunn Hadinoto Ong

submission deadline 29 Aug 2025 | Viewed by 74 | Submission Open

Keywords: deep eutectic solvent; ionic liquid drug; eutectic mixture; green solvent; pharmaceutical salts

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Thrombosis

edited by

J. Kh. Khizroeva

submission deadline 30 Aug 2025 | 6 articles | Viewed by 14530 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on the Role of the Gut Microbiota in Human Diseases and Health

edited by

Sanda Cretoiu

submission deadline 30 Aug 2025 | 5 articles | Viewed by 10783 | Submission Open

Keywords: microbiota; microbiome; gut microbiome metabolites; dysbiosis; gut– organ axis; gut microbiota pathogens; diet

(This special issue belongs to the Section Molecular Microbiology)

The Role of Extracellular Vesicles in Cancer Diagnosis and Therapy, 2nd Edition

edited by

Nils Ludwig

submission deadline 30 Aug 2025 | 3 articles | Viewed by 6708 | Submission Open

Keywords: extracellular vesicles; exosomes; intercellular communication; liquid biopsy; cancer therapeutics; nanotherapeutics

(This special issue belongs to the Section Molecular Oncology)

From Bench to Bedside: Well-Established and Emerging Preclinical Models in Cardiovascular Research

edited by

Laura Calvillo

and Veronica Dusi

submission deadline 30 Aug 2025 | 1 articles | Viewed by 4086 | Submission Open

Keywords: myocardial infarction; organ ischemia and reperfusion injury; hypertension; cardiovascular dysfunction; cardio-renal syndrome; stroke; arrhythmias; heart disease; heart failure; genetic disorders; translational medicine; organoids; bioreactors; organs on a chip; omics sciences; pharmacology; molecular biology; gene therapy; quantum biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Germline Stem Cells: New Insights

edited by

Thomas Skutella

submission deadline 30 Aug 2025 | 1 articles | Viewed by 3965 | Submission Open

Keywords: signaling pathway; spermatogonia development; oocyte development; microarray analysis; single-cell sequencing; epigenetic mechanisms; germline stem cell

(This special issue belongs to the Section Molecular Biology)

Unraveling the Molecular Mechanisms of Neurodegeneration

edited by

Michela Ferrucci

submission deadline 30 Aug 2025 | 4 articles | Viewed by 3793 | Submission Open

Keywords: protein accumulation; mitochondria; genetic and epigenetic alterations; oxidative stress; apoptosis; autophagy

(This special issue belongs to the Section Molecular Neurobiology)

Immunology of Infectious Disease and Transplantation: A Symbiotic Dance

edited by

Alessandro Perrella

submission deadline 30 Aug 2025 | 2 articles | Viewed by 3667 | Submission Open

Keywords: organ transplantation; infectious disease; immune responses; immunology; personalized medicine; transplantation medicine

(This special issue belongs to the Section Molecular Immunology)

Genetic Analysis Based on CRISPR/Cas9 Technology: 2nd Edition

edited by

Yong-Gu Cho

and

Kwon-Kyoo Kang

submission deadline 30 Aug 2025 | 2 articles | Viewed by 2980 | Submission Open

Keywords: gene targeting (GT); homology-directed repair (HDR); homology-directed gene targeting (HGT); CRISPR/Cas; targeted mutagenesis; precision breeding; genetic analysis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Transition Metal Catalysis: From Synthesis to Late-Stage Functionalization of Aromatics and Heterocycles

edited by

Antonio Del Vecchio

and

Fabio Bellina

submission deadline 30 Aug 2025 | 2 articles | Viewed by 2784 | Submission Open

Keywords: transition metal catalysis; homogeneous catalysis; heterogeneous catalysis; cross-couplings; synthesis of aromatics and heteroaromatics; late-stage functionalization; photo-; electro-; flow; mechanochemistry; medicinal chemistry; material sciences; bioinorganic chemistry; industrial processes

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Transcendental World of Plant Toxic Compounds

edited by

Helena Fernández

submission deadline 30 Aug 2025 | 1 articles | Viewed by 2098 | Submission Open

Keywords: alcaloids; biotic stress; defence; phenols; phytotoxins; secondary metabolism; terpenes

(This special issue belongs to the Section Molecular Plant Sciences)

The Extracellular Matrix in Physiopathology

edited by

Eric Huet

submission deadline 30 Aug 2025 | 1 articles | Viewed by 1738 | Submission Open

Keywords: extracellular matrix; glycosaminoglycans; matrix metalloproteinases; tissue remodeling; cell interactions; physiopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oral Soft Tissue Repair and Oral Diseases: 2nd Edition

edited by

Jacek Matys

submission deadline 30 Aug 2025 | 1 articles | Viewed by 1173 | Submission Open

Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; implant dentistry

(This special issue belongs to the Section Molecular Biology)

Intracellular Trafficking and Catabolism of Free Heme: Physiological Roles and Relevance to Pathological Mechanisms

edited by Junichi Taira

submission deadline 30 Aug 2025 | 1 articles | Viewed by 1013 | Submission Open

Keywords: heme oxygenase; heme metabolism; heme chaperon; free heme (labile heme); cytochrome P450 reductase; reactive oxygen species; carbon monoxide

(This special issue belongs to the Section Biochemistry)

Plants Redox Biology

edited by

Xin Li

submission deadline 30 Aug 2025 | 1 articles | Viewed by 789 | Submission Open

Keywords: plant– environment interaction; stress physiology; plant redox signaling; plant hormones; plant– pathogen interaction; reactive oxygen species (ROS); reactive nitrogen species (RNS); ascorbate; flavonoid; glutathione

(This special issue belongs to the Section Molecular Plant Sciences)

Beyond the Known: Molecular Insights into the World of New Psychoactive Compounds

edited by

Helena Gaspar

and

Rita Pacheco

submission deadline 30 Aug 2025 | 1 articles | Viewed by 760 | Submission Open

Keywords: new psychoactive substances; synthetic drugs; metabolism; toxicology; drug checking; designer drugs

(This special issue belongs to the Section Macromolecules)

Plant-Microbe Interaction: Current Status and Future Directions

edited by

Juan Manuel Ruiz Lozano

submission deadline 30 Aug 2025 | Viewed by 758 | Submission Open

Keywords: beneficial micro-organism; climate change; crop productivity; environmental stress; food production; plant growth; stress mitigation; yield

(This special issue belongs to the Section Molecular Plant Sciences)

Biodegradable Polymers: From Chemical Synthesis to Biodegradable Mechanism

edited by

Ling-Ping Xiao

Oana Lelia Pop

and

Gabrijel Ondrasek

submission deadline 30 Aug 2025 | Viewed by 687 | Submission Open

Keywords: biodegradable polymers; polyolefins; molecular structures; synthesis; chemical modification; hydrolysis kinetics

(This special issue belongs to the Section Macromolecules)

Innovative Technologies in the Study and Understanding of Colorectal Tumorigenesis: Challenges and Opportunities

edited by

Paola Sena

submission deadline 30 Aug 2025 | 1 articles | Viewed by 618 | Submission Open

Keywords: colorectal cancer; genetic analysis; gut microbiome; tumor; circulating components; medicine; immunotherapy; proteomics

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanism of Sympathetic Nerves in Cardiovascular Diseases and Cancer

edited by

Yutang Wang

submission deadline 30 Aug 2025 | Viewed by 489 | Submission Open

Keywords: sympathetic nerve activity; adrenergic receptors; renal denervation; heart disease; stroke; atherosclerosis; hypertension; diabetes; metabolic syndrome; cancer

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 1851-1900 on page 38 of 69.

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