Melanoma: From Molecular Pathology to Therapeutic Approaches, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 1178
Special Issue Editor
Interests: genomics; epigenomics; melanomas; human cancer; PAX genes; transcriptomic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
While melanoma is one of the most aggressive and devastating cancer types, major advances in both melanoma targeted therapy as well as immunotherapy over the past two decades have revolutionised melanoma treatment. These advances have been driven by technical innovation, which is aimed at targeting molecular pathological biomarkers, facilitating the death of melanoma cells.
However, despite these therapeutic advances, a significant proportion of melanoma patients do not benefit from these treatments, which is due to either innate or acquired treatment resistance in the melanomas.
In this Special Issue, we welcome authors to submit original research and review articles that contribute to a better understanding of molecular pathological biomarkers and mechanisms leading to treatment resistance in melanoma. Topics of interest include, but are not limited to, the following:
- Intrinsic therapeutic resistance mechanisms, immune pathways, or tumor microenvironmental factors affecting cutaneous, mucosal, uveal, or other melanoma types.
- Novel small molecules or environmental factors affecting treatment resistance or therapeutic response in melanoma.
- Individual “omics” or “integrated omics” studies of molecular (nucleotide variant, gene expression, or epigenetic) mechanisms involved in melanoma treatment response.
- Relationships between gene expression and epigenetic mechanisms of therapeutic response in melanoma.
- New therapeutic strategies (including combination therapeutic approaches) targeting melanoma tissues.
Prof. Dr. Michael Eccles
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- melanoma
- pathology
- therapeutic approaches
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