mRNA/miRNAs Network in Diabetes and Its Complications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 May 2026 | Viewed by 3043
Special Issue Editor
Special Issue Information
Dear Colleagues,
The importance of early diagnosis of diseases has been demonstrated, especially for a complex metabolic disease like diabetes mellitus (DM), for which there is a significant relative risk of complications and for which the identification of high-risk individuals could prevent progression. Early detection of the percentage of insulin-producing cells preceding loss of function would allow for effective therapeutic interventions that could delay or slow down the onset of complications. mRNA and microRNAs (miRNAs, miRs), due to their stability and presence in various body fluids, are different kinds of biomarkers that could be used for both the diagnosis and follow-up of the complications of DM. Thus, many studies have focused on the identification and validation of such mRNA/miRNA interaction networks that may prove useful in diagnosing or treating diabetes and diabetic complications. Exosome-mediated metabolic responses have also been recognized as potential targets for therapy.
In summary, the new therapeutic strategies for diabetes significantly advance our ability to treat this disease. There is hope for patients, including immunotherapy, gene therapy, and artificial pancreas systems. Adipose tissue biology and the role of mRNA/miRNA networks that act as bidirectional switches for cell therapy in damaged pancreatic tissue are also addressed.
Dr. Daniela Lixandru
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- RNA/miRNAs
- exosomes
- regenerative medicine
- translational medicine
- adipose tissue biology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
