Emerging Strategies Targeting Solid Tumors and the Tumor Microenvironment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editors
Interests: carbonic anhydrase; carbonic anhydrase inhibitors; activators; synthesis
Interests: cancer cell biology; microRNAs; pediatric brain tumors; metabolic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Cancer is a complex and heterogeneous disease that represents a significant global health burden, being one of the main causes of death worldwide. Despite significant improvements in our understanding of cancer etiology and the markers and cellular mechanisms behind its progression and aggressiveness, cancer remains a significant threat. In recent years, innovative and personalized therapeutic approaches have increased life expectancy for patients with cancer, but continuous efforts from researchers worldwide are still essential to tackling malignancies.
The aim of this Special Issue is to synthesize the latest contributions describing potential new therapeutic approaches to treating cancer. These strategies may include, but are not limited to, small-molecule agents, nanotechnologies, antibody–drug conjugates (ADCs), theragnostic agents, non-coding RNAs and drug repurposing. We are also interested in pharmacological studies aimed at identifying biochemical and metabolic pathways that could potentially be targeted to arrest cancer progression. Both original articles and reviews are welcome.
We believe that this overview of current pharmacological and medicinal chemistry approaches to treating tumor diseases will be of great interest to the scientific community.
We look forward to receiving your contributions!
Prof. Dr. Emanuela Berrino
Dr. Giuseppina Catanzaro
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- tumor microenvironment
- medicinal chemistry
- drug design
- structure–activity relationships
- nanotechnologies
- antibody–drug conjugates
- non-coding RNAs
- epigenetic
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