DNA, Chromatin and Genome Structure

Dear Colleagues,

This Special Issue commemorates the 60th anniversary of the decipherment of the genetic code by Marshall Nirenberg and colleagues—a breakthrough that launched modern molecular biology. 

DNA Structure

This section addresses DNA structure and dynamics, DNA topology, non-B DNA structures (G-quadruplexes, Z-DNA), R-loops, RNA-DNA triplexes, and extrachromosomal DNA (eccDNA). Molecular modeling of DNA and DNA hydration is also of interest. 

Chromatin Structure and Function

Topics include nucleosome positioning, chromatin conformation (Hi-C, Micro-C, 3C), chromatin compaction, TADs and chromatin loops. Chromatin functions—transcription regulation, gene regulation, DNA replication, and DNA repair—are equally relevant. Contributions on molecular modeling of chromatin are also welcome. 

Genome Organization

This theme encompasses 3D genome organization, transposable elements, chromosomal rearrangements, telomeres, centromeres, introns, noncoding DNA, and epigenetics.We invite experimental and computational contributions spanning structural biology, genomics, epigenetics, and medical genetics.

Dr. Myakishev-Rempel Max
Dr. Alexandre Vetcher
Guest Editors

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