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DNA, Chromatin and Genome Structure

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 25

Special Issue Editors


E-Mail Website
Guest Editor
DNA Resonance Research Foundation, 6294 Caminito del Oeste, San Diego, CA 92111, USA
Interests: computational genomics; transposable elements; chromatin folding; chromatin dynamics; self-organization of chromatin; electromagnetic interactions in chromatin; DNA sequence-specific chromatin folding; sequence-specific spectral resonance in DNA; functions of noncoding parts of the genome

E-Mail Website
Guest Editor
1. DNA Resonance Research Foundation, 6294 Caminito del Oeste, San Diego, CA 92111, USA
2. Institute of Pharmacy and Biotechnology (IPhB), RUDN University (RUDN), 6 Miklukho-Maklaya Str, Moscow 117198, Russian
Interests: sequence-dependent DNA secondary and ternary structure; microcicles; DNA topology; DNA-nano and microobjects interaction
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Special Issue Information

Dear Colleagues,

This Special Issue commemorates the 60th anniversary of the decipherment of the genetic code by Marshall Nirenberg and colleagues—a breakthrough that launched modern molecular biology. 

DNA Structure

This section addresses DNA structure and dynamics, DNA topology, non-B DNA structures (G-quadruplexes, Z-DNA), R-loops, RNA-DNA triplexes, and extrachromosomal DNA (eccDNA). Molecular modeling of DNA and DNA hydration is also of interest. 

Chromatin Structure and Function

Topics include nucleosome positioning, chromatin conformation (Hi-C, Micro-C, 3C), chromatin compaction, TADs and chromatin loops. Chromatin functions—transcription regulation, gene regulation, DNA replication, and DNA repair—are equally relevant. Contributions on molecular modeling of chromatin are also welcome. 

Genome Organization

This theme encompasses 3D genome organization, transposable elements, chromosomal rearrangements, telomeres, centromeres, introns, noncoding DNA, and epigenetics.We invite experimental and computational contributions spanning structural biology, genomics, epigenetics, and medical genetics.

Dr. Myakishev-Rempel Max
Dr. Alexandre Vetcher
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • DNA structure and dynamics
  • non-B DNA structures (G-quadruplexes, Z-DNA)
  • DNA topology
  • R-loops
  • RNA-DNA triplexes
  • extrachromosomal DNA (eccDNA)
  • chromatin conformation (Hi-C, Micro-C, 3C)
  • chromatin compaction
  • TADs and chromatin loops
  • three-dimensional genome organization
  • transcription regulation
  • gene regulation
  • DNA replication
  • DNA repair
  • transposable elements
  • chromosomal rearrangements
  • epigenetics
  • molecular modeling of DNA
  • molecular modeling of DNA hydration
  • molecular modeling of chromatin
  • telomeres
  • centromeres
  • introns
  • noncoding DNA

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Published Papers

This special issue is now open for submission.
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