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Research on System Biology Methods and Tools for Integrating Omics Data

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 33

Special Issue Editor


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Guest Editor
School of Life Sciences, Sun Yat-sen University, Guangzhou, China
Interests: bioinformatics; high-throughput sequencing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rapid development of high-throughput omics technologies, including genomics, transcriptomics, proteomics, metabolomics, and epigenomics, has generated increasingly complex and high-dimensional biological datasets. Traditional analytical approaches are often insufficient to uncover the full biological meaning hidden within these layers. Systems biology offers a comprehensive and integrative framework for analyzing multi-omics data, enabling researchers to model biological systems, elucidate regulatory networks, and explore disease mechanisms from a holistic perspective.

This Special Issue focuses on innovative systems biology methodologies and computational tools designed to integrate diverse omics datasets. We will highlight recent advances in integrative data analysis, network-based approaches, dynamic system modeling, and artificial intelligence-driven techniques that facilitate identifying biomarkers, therapeutic targets, and mechanistic understanding in complex biological systems.

We welcome submissions of original research articles, reviews, and software/tool descriptions that contribute to advancing multi-omics data integration, particularly in the contexts of biomedical research, biotechnology, and precision medicine.

Dr. Yuanyan Xiong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • systems biology
  • multi-omics integration
  • network analysis
  • computational biology
  • bioinformatics tools
  • machine learning
  • precision medicine

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Published Papers

This special issue is now open for submission.
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