Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 30 June 2026
Special Issue Editors
2. Biomedical Research Institute, Foundation of Research and Technology-Hellas, 45110 Ioannina, Greece
Interests: cancer epigenetics; cancer stem cells; drug resistance; breast cancer; liquid biopsies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
For this Special Issue, fundamental research endeavors to describe the molecular mechanisms driving breast cancer are warranted to ultimately develop tailored therapeutic options for this devastating disease. Recent advances in genomics and transcriptomics methodologies, such as single-cell RNA-seq and spatial transcriptomics and epigenomics, allow for the study of breast cancer cell subpopulations and their complex interactions at an unprecedented temporal and spatial resolution. The above could have important ramifications for identifying treatment-resistant populations as well as cancer cell vulnerabilities that could be precisely and effectively targeted.
We are pleased to invite you to contribute your research output towards elucidating the composition of subpopulations that constitute the complex breast tumor ecosystem, their transcriptional programs and interactions, and their responses and vulnerabilities to therapeutic regimes.
In this Special Issue, original research articles and reviews are welcome to be submitted. Research areas may include, but are not limited to, the following: transcriptomics analysis of primary breast tumor samples or cell lines at the bulk, single-cell, or spatial transcriptomics level; studies including the analysis of DNA regulatory landscapes with technologies such as ATAC-seq and ChIP-seq; and, finally, alternative approaches, applying other “omics” methodologies such as proteomics and metabolomics that contribute to a holistic systems-level understanding of the tumor milieu.
We look forward to receiving your valuable contributions.
Dr. Angeliki Magklara
Dr. Spyros Foutadakis
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast cancer
- tumor heterogeneity
- tumor microenvironment
- transcriptional regulation
- single-cell RNA-seq
- spatial transcriptomics
- genomics
- epigenomics
- proteomics
- metabolomics
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