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Epigenetic Markers of Cancer Diseases

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 130

Special Issue Editors


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Guest Editor
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Interests: epigenetic biomarkers; DNA methylation profiling; chromatin remodeling; neuroendocrine tumors; precision oncology; translational cancer research; epigenetic therapeutics; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Interests: neuroendocrine tumors; radiation therapy; pathology; cytology; genomics; epigenetics; pediatric oncology; targeted therapy

Special Issue Information

Dear Colleagues,

Epigenetic changes drive cancer initiation and progression at every stage. DNA methylation, histone modifications, and expression patterns alter gene activity without changing the genetic code itself. These changes silence tumor suppressors and activate oncogenes, creating conditions that favor tumor growth.

Over the past two decades, research has revealed how specific epigenetic markers serve as reliable indicators of cancer risk, early detection, and disease progression. These markers hold real diagnostic and prognostic value across multiple cancer types. They offer clinicians a window into tumor behavior that traditional genetic testing alone cannot provide.

Epigenetic modifications are also reversible. This biological feature makes them attractive targets for therapeutic intervention. Drugs such as DNA methyltransferase inhibitors and histone deacetylase inhibitors have already shown clinical promise in hematologic malignancies and are under active investigation in solid tumors.

This Special Issue invites original research, reviews, and commentary focused on epigenetic markers across all cancer types. We welcome submissions covering biomarker discovery, diagnostic applications, therapeutic targeting, and clinical translation of epigenetic findings.

We encourage researchers across oncology, molecular biology, and clinical medicine to contribute. Your work will help advance our collective understanding of how epigenetics shapes cancer biology and patient outcomes.

We look forward to receiving your contributions.

Dr. Himanshu Narayan Singh
Guest Editor

Dr. Jessica Puzzuoli
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epigenetics
  • DNA methylation
  • histone modifications
  • tumor suppressor genes
  • oncogenes
  • cancer biomarkers
  • early detection
  • disease progression
  • epigenetic therapy
  • DNA methyltransferase inhibitors
  • histone deacetylase inhibitors
  • liquid biopsy
  • cancer risk assessment
  • clinical translation

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This special issue is now open for submission.
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