The Role of Sphingolipids in Cancer Progression
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 30 October 2026 | Viewed by 109
Special Issue Editor
Interests: sphingolipid metabolism; drug mechanism-of-action; neuroblastoma; polyamines; pediatric cancer; pre-clinical translational studies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Our understanding of the role of sphingolipids in the progression of cancer is ever-evolving. With the advent of techniques such as spatial transcriptomics, proteomics and metabolomics, we will undoubtedly discover novel roles for well-characterized sphingolipids, such as sphingosine-1-phosphate and ceramide, and the enzymes that catalyze their generation. However, it is also likely that less studied sphingolipids and sphingolipid metabolizing enzymes will be increasingly recognized as important modulators of cancer progression. This Special Issue is designed to highlight methods and strategies that reveal these rare sphingolipids/enzymes and their role(s) in the development, progression and metastasis of cancer. A better understanding of how sphingolipids influence tumor development will hopefully lead to the identification of novel sphingolipid targets and novel therapeutic strategies to block tumorigenesis and/or tumor progression.
Dr. Jeremy Hengst
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- sphingolipids
- tumorigenesis
- tumor progression
- metastasis
- spatial transcriptomics
- spatial metabolomics
- spatial proteomics
- transcriptomics
- metabolomics
- proteomics
- drug development
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