Novel Strategies to Fight Metastatic Breast Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 1001
Special Issue Editors
Interests: molecular pathology; cytopathology; breast cancer
Special Issues, Collections and Topics in MDPI journals
Interests: in silico pharmacology; PBPK; drug metabolism; drug combination; drug delivery; peptides; ADME; DMPK; pharmacokinetic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Breast cancer remains the most common malignancy among women and the second cause of cancer-related mortality in females. This highly heterogeneous disease is classified based on molecular and histological characteristics. Considering their molecular classification, tumours are divided into four main subtypes, determined by the expression levels of hormone receptors (HRs), human epidermal growth factor receptor 2 (HER2), and Ki-67. Therefore, depending on the tumour classification, different prognoses and treatment options are conferred. Despite the advances in early tumour detection, surgery, radiotherapy, and chemotherapy, several challenges persist in breast cancer treatment, especially due to drug resistance, resulting in tumour recurrence and metastasis. Recently, several studies have focused on understanding the evolution of breast tumours, exploring, for example, metabolic reprogramming and immune responses with the aim of finding new therapeutic targets.
Thus, continuous investigation in this area, especially in metastatic disease, and searching for new biomarker predictors of metastasis and new targetable pathways/mutations are crucial to improving patients’ outcomes and increasing the application of personalized medicine.
This Special Issue aims to provide a comprehensive update on metastatic breast cancer therapy, emphasizing novel targetable mutations, mechanisms of resistance, and new biomarkers that can predict breast tumour metastasis, allowing for early targeted treatment and disease monitoring. We welcome original articles and reviews addressing these advances.
We look forward to your contributions.
Prof. Dr. Fernando Schmitt
Prof. Dr. Nuno Vale
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast cancer
- metastasis
- targeted therapy
- biomarkers
- personalized medicine
- prognosis
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