Genetic Alterations and Features in the Development of Gastrointestinal Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 83
Special Issue Editor
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) cancers develop through the multifaceted interplay of genetic alterations, epigenetic changes, and environmental influences. Beyond somatic mutations and chromosomal instability, factors such as diet, nutrition, chronic infections (e.g., Helicobacter pylori, hepatitis viruses), and gut microbiome dysbiosis significantly contribute to tumorigenesis and progression. These elements can modulate inflammation, immune response, and even mutational landscapes. This Special Issue welcomes original research and reviews exploring the molecular, microbial, infectious, and lifestyle-related determinants of GI cancers. By integrating basic, translational, and clinical perspectives, we aim to advance precision prevention, diagnostics, and therapy in this diverse and impactful disease group.
Dr. Alexandra Voutsina
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- gastrointestinal cancers
- genetic alteration
- epigenetic regulation
- the mechanism of tumorigenesis
- precision treatment
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