Genetic Alterations and Features in the Development of Gastrointestinal Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 29
Special Issue Editor
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) cancers develop through the multifaceted interplay of genetic alterations, epigenetic changes, and environmental influences. Beyond somatic mutations and chromosomal instability, factors such as diet, nutrition, chronic infections (e.g., Helicobacter pylori, hepatitis viruses), and gut microbiome dysbiosis significantly contribute to tumorigenesis and progression. These elements can modulate inflammation, immune response, and even mutational landscapes. This Special Issue welcomes original research and reviews exploring the molecular, microbial, infectious, and lifestyle-related determinants of GI cancers. By integrating basic, translational, and clinical perspectives, we aim to advance precision prevention, diagnostics, and therapy in this diverse and impactful disease group.
Dr. Alexandra Voutsina
Guest Editor
Manuscript Submission Information
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Keywords
- gastrointestinal cancers
- genetic alteration
- epigenetic regulation
- the mechanism of tumorigenesis
- precision treatment
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