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The Function of the MYC Network in Normal and Neoplastic Tissues

A Special Issue of Cancers (ISSN 2072-6694) belonging to the section "Molecular Cancer Biology".

Deadline for manuscript submissions: 1 January 2027 | Viewed by 204

Editors


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Guest Editor
Section of Hematology/Oncology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA
Interests: MYC’s role in metabolism, aging and transcription; therapeutic targeting of MYC
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA
Interests: MYC; oncogene; cancer targeted therapy

Special Issue Information

Dear Colleagues,

The MYC oncoprotein is expressed by virtually all proliferating normal cells and is over-expressed and/or deregulated by the majority of naturally occurring and experimental cancers. Since its discovery over 40 years ago, MYC has been implicated in an ever-expanding number of cellular processes that go awry during cancer development and that converge upon and facilitate proliferation. These processes include, but are not limited to transcription, enhancer function, metabolism, cell cycle control, DNA damage repair, ribosomal biogenesis, translation, apoptosis and senescence, differentiation and aging. MYC’s unique position in cancer pathogenesis, as well as its ability to regulate the immune micro-environment, has also highlighted its importance as a critical therapeutic target. This Special Issue seeks to highlight new and emerging original discoveries pertaining to MYC’s role in normal and neoplastic cellular functions. We are interested in soliciting both original research and comprehensive review articles that will serve as topical resources for the above aspects of MYC function. Also of interest are articles pertaining to other members of the MYC family (e.g., MYCN) or the MYC-like MLX Network.

Prof. Dr. Edward Prochownik
Prof. Dr. Dean W. Felsher
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aging
  • cancer
  • enhancers
  • ribosomes
  • transcription
  • tumor metabolism
  • tumor suppressors
  • Warburg effect

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Published Papers

This special issue is now open for submission.
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