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Journal of Clinical Medicine, Volume 12, Issue 3

2023 February-1 - 513 articles

Cover Story: Pulmonary vein isolation (PVI) is increasingly important for the treatment of the ever-increasing number of patients with atrial fibrillation. Therefore, continuous improvement of the PVI workflow is urgently needed. The aim of this study was to evaluate the impact of omitting pulmonary vein (PV) angiography before ablation on the safety and efficacy of PVI. For this purpose, patients who received PVI with PV angiography were compared with patients who received PVI without PV angiography. Apart from the fact that the fluoroscopy dose and the amount of contrast agent were significantly reduced when PV angiography was omitted, there were no differences between the groups. Thus, it can be useful to avoid PV angiography especially in young patients and those with chronic kidney disease. View this paper
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Articles (513)

  • Article
  • Open Access
2 Citations
4,601 Views
12 Pages

Daytime Variation of Chloral Hydrate-Associated Sedation Outcomes: A Propensity-Matched Cohort Study

  • Yu Cui,
  • Langtao Guo,
  • Li Xu,
  • Qixia Mu,
  • Qunying Wu,
  • Lu Kang,
  • Qin Chen,
  • Yani He and
  • Hong Liu

3 February 2023

Background: Physiological processes influencing a drugs’ efficacy change substantially over the course of the day. However, it is unclear whether there is an association between the sedative success rate of chloral hydrate and the time of day....

(This article belongs to the Section Pharmacology)
  • Review
  • Open Access
22 Citations
5,641 Views
15 Pages

The Relationship between Social Support and Anxiety Symptoms in Informal Carers: A Systematic Review and Meta-Analysis

  • Emilia Priego-Cubero,
  • Vasiliki Orgeta,
  • Catalina López-Martínez and
  • Rafael del-Pino-Casado

3 February 2023

Background: Providing care can be challenging for informal carers and increases the risk of mental health problems, such as experiencing clinical symptoms of anxiety. While strengthening social support for informal carers is a common recommendation t...

(This article belongs to the Section Mental Health)
  • Review
  • Open Access
39 Citations
27,740 Views
21 Pages

Post-Inflammatory Hypopigmentation: Review of the Etiology, Clinical Manifestations, and Treatment Options

  • Medha Rao,
  • Katherine Young,
  • Ladonya Jackson-Cowan,
  • Arianne Kourosh and
  • Nicholas Theodosakis

3 February 2023

Post-inflammatory hypopigmentation is a common acquired pigmentary disorder that is more prominent in skin of color, leading to great cosmetic and psychosocial implications. Often, a diagnosis with a pigmentary disorder can negatively impact an indiv...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
11 Citations
3,573 Views
11 Pages

Relationships between 25-Hydroxyvitamin D Levels and Obstructive Sleep Apnea Severity in Children: An Observational Study

  • Cristian Locci,
  • Antonella Ruiu,
  • Laura Saderi,
  • Giovanni Sotgiu,
  • Stefania Bassu,
  • Marco Zaffanello and
  • Roberto Antonucci

3 February 2023

The prevalence of hypovitaminosis D is increasing worldwide. Vitamin D deficiency is supposed to play a role in sleep disturbances, but the complex relationships between hypovitaminosis D and pediatric obstructive sleep apnea syndrome (OSAS) are stil...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
12 Citations
4,951 Views
17 Pages

Planned Extracorporeal Life Support Employment during Liver Transplantation: The Potential of ECMO and CRRT as Preventive Therapies—Case Reports and Literature Review

  • Cristiana Laici,
  • Amedeo Bianchini,
  • Noemi Miglionico,
  • Niccolò Bambagiotti,
  • Giovanni Vitale,
  • Guido Fallani,
  • Matteo Ravaioli and
  • Antonio Siniscalchi

3 February 2023

Liver Transplantation (LT) has become the gold standard treatment for End-Stage Liver Disease (ESLD). One of the main strategies to manage life-threatening complications, such as cardio-respiratory failure, is Extracorporeal Membrane Oxygenation (ECM...

(This article belongs to the Special Issue Liver Transplantation: Current Challenges and New Perspectives)
  • Article
  • Open Access
8 Citations
7,294 Views
6 Pages

Does Post-COVID-19 Erectile Dysfunction Improve over Time?

  • Alper Gök,
  • Mehmet Altan,
  • Ahmet Emin Doğan,
  • Aşır Eraslan,
  • Fahrettin Şamil Uysal,
  • Ufuk Öztürk,
  • Ardan Muammer Saguner and
  • Muhammet Abdurrahim İmamoğlu

3 February 2023

Background: Some studies have shown that there may be an increase in the frequency of erectile dysfunction after COVID-19. However, no long-term study has investigated whether this is permanent or temporary. In this study, we aimed to examine whether...

(This article belongs to the Section Reproductive Medicine & Andrology)
  • Article
  • Open Access
6 Citations
2,513 Views
11 Pages

Mild Acquired von Willebrand Syndrome and Cholestasis in Pediatric and Adult Patients with Fontan Circulation

  • Katharina Meinel,
  • Felicitas Korak,
  • Martin Dusleag,
  • Tanja Strini,
  • Daniela Baumgartner,
  • Ante Burmas,
  • Hannes Sallmon,
  • Barbara Zieger,
  • Axel Schlagenhauf and
  • Martin Koestenberger

3 February 2023

Background: Hemodynamic alterations in Fontan patients (FP) are associated with hemostatic dysbalance and Fontan-associated liver disease. Studies of other hepatopathologies indicate an interplay between cholestasis, tissue factor (TF), and von Wille...

(This article belongs to the Special Issue Clinical Research Advances in Congenital Heart Disease)
  • Review
  • Open Access
64 Citations
11,833 Views
18 Pages

Stent Thrombosis and Restenosis with Contemporary Drug-Eluting Stents: Predictors and Current Evidence

  • Francesco Condello,
  • Carmen Spaccarotella,
  • Sabato Sorrentino,
  • Ciro Indolfi,
  • Giulio G. Stefanini and
  • Alberto Polimeni

3 February 2023

Iterations in stent technologies, advances in pharmacotherapy, and awareness of the implications of implantation techniques have markedly reduced the risk of stent failure, both in the form of stent thrombosis (ST) and in-stent restenosis (ISR). Howe...

(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Coronary Artery Disease)
  • Review
  • Open Access
30 Citations
15,417 Views
16 Pages

Current Therapeutic Strategies for Patients with Hypopharyngeal Carcinoma: Oncologic and Functional Outcomes

  • Alexandre Bozec,
  • Gilles Poissonnet,
  • Olivier Dassonville and
  • Dorian Culié

3 February 2023

Hypopharyngeal cancer is usually diagnosed at an advanced stage and is associated with a high risk of recurrence and poor survival rates. Although they differ greatly in terms of prognosis, hypopharyngeal cancers are usually treated together with lar...

(This article belongs to the Special Issue Diagnosis, Treatment and Management in Head and Neck Squamous Cell Carcinoma)
  • Essay
  • Open Access
9 Citations
2,744 Views
11 Pages

3 February 2023

Background: Data on the outcomes of restrictive cardiomyopathy (RCM) are limited, when the condition is complicated with arrhythmia. This study was designed to investigate the prevalence of atrial fibrillation (AF), ventricular tachycardia (VT) and b...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
9 Citations
2,718 Views
10 Pages

3 February 2023

Introduction: As has been established, the left ventricle (LV) and the left atrium (LA) form an organic unit of the left heart; however, little is known about the dependence of LV rotational parameters on LA volumes, even in healthy circumstances. Th...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
3 Citations
3,140 Views
10 Pages

Opportunistic Genetic Screening for Familial Hypercholesterolemia in Heart Transplant Patients

  • María Salgado,
  • Beatriz Díaz-Molina,
  • Elías Cuesta-Llavona,
  • Andrea Aparicio,
  • María Fernández,
  • Vanesa Alonso,
  • Pablo Avanzas,
  • Isaac Pascual,
  • David Neuhalfen and
  • Rebeca Lorca
  • + 2 authors

3 February 2023

Heart transplantation remains the gold standard for the treatment of advanced heart failure (HF). Identification of the etiology of HF is mandatory, as the specific pathology can determine subsequent treatment. Early identification of familial hyperc...

(This article belongs to the Special Issue Dyslipidemia and Cardiovascular Disease)
  • Article
  • Open Access
5 Citations
8,145 Views
14 Pages

Echocardiographic Parameters to Predict Malignant Events in Arrhythmic Mitral Valve Prolapse Population

  • Alessandro Vairo,
  • Paolo Desalvo,
  • Andrea Rinaudo,
  • Francesco Piroli,
  • Anna Tribuzio,
  • Andrea Ballatore,
  • Gianluca Marcelli,
  • Lorenzo Pistelli,
  • Veronica Dusi and
  • Carla Giustetto
  • + 8 authors

3 February 2023

Bileaflet Mitral Valve Prolapse (bMVP) has been linked to major arrhythmic events and sudden cardiac death (SCD). Consistent predictors in this field are still lacking. Echocardiography is the best tool for the analysis of the prolapse and its impact...

(This article belongs to the Collection The Development and Application of Echocardiography in Heart Disease)
  • Article
  • Open Access
3 Citations
3,031 Views
10 Pages

3 February 2023

In order to explore the factors affecting patients’ level of activities of daily living (ADL) on discharge after undergoing bipolar hemiarthroplasty or total hip arthroplasty for displaced femoral neck fractures at an acute care hospital, patie...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
11 Citations
4,114 Views
16 Pages

3 February 2023

There is a trend towards the formalization of the rehabilitation process for older rehabilitants in a Challenging Rehabilitation Environment (CRE). This concept involves the comprehensive organization of care, support, and environment on rehabilitati...

(This article belongs to the Section Clinical Rehabilitation)
  • Review
  • Open Access
16 Citations
7,419 Views
27 Pages

3 February 2023

Current descriptions of the history of subtotal cholecystectomy require more details and accuracy. This study presented a narrative review of the articles on partial resections of the gallbladder published between 1898 and 2022. The Scale for the Ass...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Perspective
  • Open Access
19 Citations
7,002 Views
10 Pages

Retinopathy of Prematurity in the 21st Century and the Complex Impact of Supplemental Oxygen

  • Sarah H. Rodriguez,
  • Anna L. Ells,
  • Michael P. Blair,
  • Parag K. Shah,
  • C. Armitage Harper,
  • Maria Ana Martinez-Castellanos,
  • S. Grace Prakalapakorn,
  • Erima Denis,
  • Rebecca C. Lusobya and
  • Lucy Namakula
  • + 5 authors

3 February 2023

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. Not only do the epidemiologic determinants and distributions of patients with ROP vary worldwide, but clinical differences have also been described. The Third Edition of the...

(This article belongs to the Section Ophthalmology)
  • Opinion
  • Open Access
1 Citations
3,585 Views
8 Pages

3 February 2023

Neuroendocrine tumors are a rare type of cancer found in hormone-producing cells throughout the body. Research on disease-specific patient education assessments in this population is lacking. We previously demonstrated the feasibility and validity of...

(This article belongs to the Special Issue Integrating Clinical and Translational Research Networks—Building Team Medicine - Series 2)
  • Article
  • Open Access
1 Citations
8,696 Views
13 Pages

The Study of a Validated Assessment Scale for a Localized Submental Fat Volume

  • Joon-Seok Oh,
  • Jinil Choi,
  • Jong-Woo Choi,
  • Dae-Hyun Lew,
  • Tai-Suk Roh,
  • Seung-Yong Song,
  • Young-Seok Kim,
  • Hojin Park,
  • Sang-Woong Youn and
  • Chan-Yeong Heo
  • + 3 authors

3 February 2023

Background: This aim of this study was to develop an objective tool for rating submental fat applied to Koreans. Methods: The study was conducted between April 2019 and October 2019. A total of 92 subjects were enrolled in the study. Clinical photos...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
7 Citations
2,768 Views
12 Pages

A Nomogram Model Based on Neuroendocrine Markers for Predicting the Prognosis of Neuroendocrine Carcinoma of Cervix

  • Mingzhu Jia,
  • Jiangchuan Pi,
  • Juan Zou,
  • Min Feng,
  • Huiling Chen,
  • Changsheng Lin,
  • Shuqi Yang,
  • Ying Deng and
  • Xue Xiao

3 February 2023

Background: Combining traditional clinical parameters with neuroendocrine markers to construct a nomogram model to predict the postoperative recurrence of neuroendocrine carcinoma of cervix (NECC). Methods: A total of 257 patients were included in th...

(This article belongs to the Special Issue Polycystic Ovary Syndrome: Aetiology, Diagnosis, Treatment and Future Perspectives)
  • Article
  • Open Access
2 Citations
3,510 Views
12 Pages

Cellular and Humoral Responses to Recombinant and Inactivated SARS-CoV-2 Vaccines in CKD Patients: An Observational Study

  • Siliang Zhang,
  • Jiaoxia He,
  • Bin Tang,
  • Qin Zhou,
  • Yudong Hu,
  • Yuan Yu,
  • Jianwei Chen,
  • Yi Liu,
  • Chunmeng Li and
  • Xiaohui Liao
  • + 1 author

3 February 2023

Background: It remains unclear what B cell and humoral responses are mounted by chronic kidney disease (CKD) patients in response to recombinant and inactivated SARS-CoV-2 vaccines. In this study, we aimed to explore the cellular and humoral response...

(This article belongs to the Special Issue COVID-19: Clinical Advances and Challenges)
  • Article
  • Open Access
14 Citations
4,870 Views
15 Pages

Use of Direct Acting Oral Anticoagulants in Elderly Patients with Atrial Fibrillation: A Multicenter, Cross-Sectional Study in Spain

  • Pablo Díez-Villanueva,
  • Juan Cosín-Sales,
  • Vanesa Roldán-Schilling,
  • Vivencio Barrios,
  • Diana Riba-Artés and
  • Olga Gavín-Sebastián

3 February 2023

Non-vitamin K antagonist oral anticoagulants (NOACs) have substantially improved anticoagulation. However, data on NOAC use among elderly patients are scarce. We sought to describe NOAC use among elderly AF patients in Spain. We performed a non-inter...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
25 Citations
4,442 Views
14 Pages

Trends in Unhealthy Lifestyle Factors among Adults with Stroke in the United States between 1999 and 2018

  • Yuting Liu,
  • Haochen Wang,
  • Bingqing Bai,
  • Fengyao Liu,
  • Yilin Chen,
  • Yu Wang,
  • Yanting Liang,
  • Xiaohe Shi,
  • Xueju Yu and
  • Qingshan Geng
  • + 3 authors

3 February 2023

BACKGROUND: Unhealthy lifestyle factors are risk factors for stroke, and they play a key role in stroke secondary prevention. A better understanding of these factors may aid with improvements in public health policy. OBJECTIVE: Our objective was to c...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
1 Citations
2,383 Views
10 Pages

Effect of Supplemental Oxygen on von Willebrand Factor Activity and Ristocetin Cofactor Activity in Patients at Risk for Cardiovascular Complications Undergoing Moderate-to High-Risk Major Noncardiac Surgery—A Secondary Analysis of a Randomized Trial

  • Katharina Horvath,
  • Alexander Taschner,
  • Nikolas Adamowitsch,
  • Markus Falkner von Sonnenburg,
  • Edith Fleischmann,
  • Barbara Kabon,
  • Melanie Fraunschiel,
  • Christian Reiterer and
  • Alexandra Graf

3 February 2023

Increased von Willebrand Factor (vWF) activity mediates platelet adhesion and might be a contributor to the development of thrombotic complications after surgery. Although in vitro studies have shown that hyperoxia induces endovascular damage, the ef...

(This article belongs to the Special Issue Anesthetic Management in Perioperative Period)
  • Review
  • Open Access
62 Citations
19,491 Views
13 Pages

PCOS in Adolescents—Ongoing Riddles in Diagnosis and Treatment

  • Blazej Meczekalski,
  • Olga Niwczyk,
  • Anna Kostrzak,
  • Marzena Maciejewska-Jeske,
  • Gregory Bala and
  • Anna Szeliga

3 February 2023

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. A diagnosis of PCOS is established when a patient exhibits two of three Rotterdam criteria: oligoovulation or anovulation, excess androgen ac...

(This article belongs to the Section Obstetrics & Gynecology)
  • Article
  • Open Access
14 Citations
5,335 Views
14 Pages

Machine Learning Predictive Models for Evaluating Risk Factors Affecting Sperm Count: Predictions Based on Health Screening Indicators

  • Hung-Hsiang Huang,
  • Shang-Ju Hsieh,
  • Ming-Shu Chen,
  • Mao-Jhen Jhou,
  • Tzu-Chi Liu,
  • Hsiang-Li Shen,
  • Chih-Te Yang,
  • Chung-Chih Hung,
  • Ya-Yen Yu and
  • Chi-Jie Lu

3 February 2023

In many countries, especially developed nations, the fertility rate and birth rate have continually declined. Taiwan’s fertility rate has paralleled this trend and reached its nadir in 2022. Therefore, the government uses many strategies to encourage...

(This article belongs to the Section Reproductive Medicine & Andrology)
  • Article
  • Open Access
13 Citations
3,682 Views
17 Pages

3 February 2023

Heart rate asymmetry (HRA) reflects different contributions of heart rate (HR) decelerations and accelerations to heart rate variability (HRV). In this study, we examined various properties of HRA, including its compensation and HRV, in 48-h electroc...

(This article belongs to the Special Issue Cardiovascular Time Series in the Preclinical and Clinical Settings)
  • Article
  • Open Access
7 Citations
3,324 Views
11 Pages

Shoulder Joint Hybrid Assistive Limb Treatment for Chronic Stroke Patients with Upper Limb Dysfunction

  • Masakazu Taketomi,
  • Yukiyo Shimizu,
  • Hideki Kadone,
  • Shigeki Kubota,
  • Yuta Kagai,
  • Yoshitaka Okamoto,
  • Yasushi Hada and
  • Masashi Yamazaki

3 February 2023

Upper extremity dysfunction after stroke affects quality of life. Focusing on the shoulder joint, we investigated the safety and effectiveness of rehabilitation using a shoulder joint hybrid assistive limb (HAL). Eight patients with chronic stroke an...

(This article belongs to the Special Issue Clinical Evaluation, Treatment and Prognostication of Ischemic Stroke Patients)
  • Article
  • Open Access
11 Citations
2,759 Views
10 Pages

Acute Modification of Hemodynamic Forces in Patients with Severe Aortic Stenosis after Transcatheter Aortic Valve Implantation

  • Alessandro Vairo,
  • Lorenzo Zaccaro,
  • Andrea Ballatore,
  • Lorenzo Airale,
  • Fabrizio D’Ascenzo,
  • Gianluca Alunni,
  • Federico Conrotto,
  • Luca Scudeler,
  • Daniela Mascaretti and
  • Gaetano Maria De Ferrari
  • + 5 authors

3 February 2023

Transcatheter aortic valve implantation (TAVI) is the established first-line treatment for patient with severe aortic stenosis not suitable for surgery. Echocardiographic evaluation of hemodynamic forces (HDFs) is a growing field, holding the potenti...

(This article belongs to the Topic Cardiac Imaging: State of the Art)
  • Systematic Review
  • Open Access
14 Citations
5,454 Views
13 Pages

3 February 2023

Recurrent laryngeal nerve (RLN) injury is a well and long-known complication of thyroid and parathyroid surgery that significantly affects the quality of life of patients. Despite the advances in surgical techniques and technology, it still occurs in...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
8 Citations
3,085 Views
11 Pages

A Neural Network for Automated Image Quality Assessment of Optic Disc Photographs

  • Ella Bouris,
  • Tyler Davis,
  • Esteban Morales,
  • Lourdes Grassi,
  • Diana Salazar Vega and
  • Joseph Caprioli

3 February 2023

This study describes the development of a convolutional neural network (CNN) for automated assessment of optic disc photograph quality. Using a code-free deep learning platform, a total of 2377 optic disc photographs were used to develop a deep CNN c...

(This article belongs to the Special Issue Big Data and Artificial Intelligence-Driven Research in Ophthalmology)
  • Article
  • Open Access
6 Citations
4,514 Views
13 Pages

A Standardized Operative Protocol for Fixation of Proximal Humeral Fractures Using a Locking Plate to Minimize Surgery-Related Complications

  • Sebastian Kwisda,
  • Jan-Philipp Imiolczyk,
  • Tankred Imiolczyk,
  • Magdalena Werth and
  • Markus Scheibel

3 February 2023

The current literature suggests that up to 55% of complications after plate osteosynthesis treatment for patients with proximal humerus fractures are attributed to the surgical procedure. The hypothesis of this study was that a standardized surgical...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
5 Citations
3,236 Views
12 Pages

Assessment of Retinal Pigment Epithelium Alterations and Chorioretinal Vascular Network Analyses in Patients under Treatment with BRAF/MEK Inhibitor for Different Malignancies: A Pilot Study

  • Giuseppe Fasolino,
  • Gil Awada,
  • Laura Moschetta,
  • Jorgos Socrates Koulalis,
  • Bart Neyns,
  • Bert Verhelst,
  • Peter Van Elderen,
  • Pieter Nelis,
  • Paul Cardon de Lichtbuer and
  • Marcellinus Ten Tusscher
  • + 1 author

3 February 2023

In the last two decades, an increasing number of so-called molecular-targeted therapies have become available for the treatment of patients with advanced malignancies. These drugs have included inhibitors of proteins in the MAPK pathway, such as BRAF...

(This article belongs to the Section Ophthalmology)
  • Editorial
  • Open Access
7 Citations
2,765 Views
5 Pages

3 February 2023

The impact of the COVID-19 pandemic on mental health has unveiled the complexity of the relationship between psychiatry and the rest of medicine, as clearly shown by the collection of studies published in this Special Issue entitled “Mental Hea...

(This article belongs to the Special Issue Mental Health Challenges during the COVID-19 Pandemic)
  • Article
  • Open Access
1 Citations
2,596 Views
11 Pages

The Impact of Prematurity at Birth on Short-Term Postoperative Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

  • Neil V. Shah,
  • Marine Coste,
  • Adam J. Wolfert,
  • Samuel Gedailovich,
  • Brian Ford,
  • David J. Kim,
  • Nathan S. Kim,
  • Chibuokem P. Ikwuazom,
  • Neil Patel and
  • Bassel G. Diebo
  • + 5 authors

3 February 2023

Prematurity is associated with surgical complications. This study sought to determine the risk of prematurity on 30-day complications, reoperations, and readmissions following ≥7-level PSF for AIS which has not been established. Utilizing the Amer...

(This article belongs to the Special Issue Spinal Disorders: Current Treatment and Future Opportunities: Part II)
  • Article
  • Open Access
2 Citations
2,168 Views
12 Pages

Impact of Endophthalmitis on the Risk of Acute Myocardial Infarction in Ankylosing Spondylitis Patients: A Population-Based Retrospective Cohort Study

  • Ting-Yi Lin,
  • Yi-Fen Lai,
  • Wu-Chien Chien,
  • Yi-Hao Chen,
  • Chi-Hsiang Chung,
  • Jiann-Torng Chen and
  • Ching-Long Chen

3 February 2023

Many studies have demonstrated an increased cardiovascular (CV) risk in ankylosing spondylitis (AS) patients. Nevertheless, the influence of an endophthalmitis episode toward the future risks of acute myocardial infarction (AMI) in AS patients has be...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
5 Citations
2,989 Views
11 Pages

3 February 2023

Hemiarthroplasty and total hip arthroplasty are routinely performed procedures. A comparison of these procedures in tumor patients can be performed based on complications and functional outcomes. To weigh the advantages and disadvantages of both proc...

(This article belongs to the Special Issue State of the Art: The Current Concept of Multidisciplinary Management of Musculoskeletal Tumor)
  • Article
  • Open Access
4 Citations
3,506 Views
15 Pages

2 February 2023

Factors affecting the progression rate and fate of osteoarthritis need to be analyzed when considering patient-specific situation. This study aimed to identify the rate of remarkable progression and fate of primary knee osteoarthritis based on patien...

(This article belongs to the Section Orthopedics)
  • Review
  • Open Access
70 Citations
18,625 Views
18 Pages

Latest Evidence on Post-Prostatectomy Urinary Incontinence

  • Mauro Gacci,
  • Cosimo De Nunzio,
  • Vasileios Sakalis,
  • Malte Rieken,
  • Jean-Nicolas Cornu and
  • Stavros Gravas

2 February 2023

A radical prostatectomy is frequently used as the first-line treatment for men with prostate cancer. Persistent urinary incontinence after surgery is one of the most severe adverse events. We report the results of a comprehensive literature search fo...

(This article belongs to the Special Issue Latest Advances in Urinary Incontinence)
  • Article
  • Open Access
2 Citations
2,307 Views
13 Pages

The Relative Contributions of Occupational and Community Risk Factors for COVID-19 among Hospital Workers: The HOP-COVID Cohort Study

  • Sylvie Bastuji-Garin,
  • Ludivine Brouard,
  • Irma Bourgeon-Ghittori,
  • Sonia Zebachi,
  • Emmanuelle Boutin,
  • Francois Hemery,
  • Frédéric Fourreau,
  • Nadia Oubaya,
  • Quentin De Roux and
  • Jean-Winoc Decousser
  • + 2 authors

2 February 2023

The relative contributions of occupational and community sources of COVID-19 among health-care workers (HCWs) are still subject to debate. In a cohort study at a 2814-bed tertiary medical center (five hospitals) in the Paris area of France, we assess...

(This article belongs to the Special Issue Epidemiology and Clinical Characteristics of COVID-19)
  • Article
  • Open Access
15 Citations
4,995 Views
18 Pages

Predictive Factors of Suicidal Ideation in Spanish University Students: A Health, Preventive, Social, and Cultural Approach

  • Cristina Lázaro-Pérez,
  • Pilar Munuera Gómez,
  • José Ángel Martínez-López and
  • José Gómez-Galán

2 February 2023

Suicide, as the ultimate expression of suicidal ideation, has accompanied human beings throughout history within specific social and cultural contexts. However, in recent decades the increase in suicides, especially in developed countries after the S...

(This article belongs to the Special Issue Triggers of Suicidal Ideation: Multidisciplinary Approach)
  • Systematic Review
  • Open Access
51 Citations
22,576 Views
30 Pages

Clinical Effectiveness of Dry Needling in Patients with Musculoskeletal Pain—An Umbrella Review

  • Marjolein Chys,
  • Kayleigh De Meulemeester,
  • Indra De Greef,
  • Carlos Murillo,
  • Wouter Kindt,
  • Yassir Kouzouz,
  • Bavo Lescroart and
  • Barbara Cagnie

2 February 2023

The number of systematic reviews (SR) summarizing the literature regarding the clinical effects of Dry Needling (DN) has increased rapidly. Yet, rigorous evidence about the clinical effectiveness of this technique is still lacking. The aim of this um...

(This article belongs to the Special Issue Needling Interventions for the Management of Musculoskeletal Pain Syndromes—Volume II)
  • Article
  • Open Access
8 Citations
3,253 Views
9 Pages

Clinical Outcomes with and without Adherence to Evidence-Based Medicine Guidelines for Lumbar Degenerative Spondylolisthesis Fusion Patients

  • Glenn A. Gonzalez,
  • Guilherme Porto,
  • Kevin Hines,
  • Daniel Franco,
  • Thiago S. Montenegro,
  • Aria Mahtabfar,
  • Matthew O’Leary,
  • Jingya Miao,
  • Sara Thalheimer and
  • James Harrop
  • + 2 authors

2 February 2023

Introduction: Degenerative lumbar spondylolisthesis (DS) patients are treated with instrumented fusion, following EBM guidelines, and typically have excellent clinical outcomes. However, not all lumbar fusion procedures adhere to EBM guidelines, typi...

(This article belongs to the Section Orthopedics)
  • Systematic Review
  • Open Access
38 Citations
11,814 Views
18 Pages

Diagnostic Accuracy of Fecal Calprotectin for Predicting Relapse in Inflammatory Bowel Disease: A Meta-Analysis

  • Jin-Tong Shi,
  • Nuo Chen,
  • Jia Xu,
  • Hemant Goyal,
  • Zhi-Qi Wu,
  • Jie-Xin Zhang and
  • Hua-Guo Xu

2 February 2023

Fecal calprotectin (FC) levels correlate with the disease activity of inflammatory bowel diseases (IBD); however, the utility of FC in predicting IBD relapse remains to be determined. We aim to evaluate the efficacy of fecal calprotectin in predictin...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
6 Citations
4,824 Views
11 Pages

2 February 2023

Mild cognitive impairment (MCI) is the preliminary stage of dementia, which is a serious social problem worldwide. This study aimed to investigate whether the Cognitive Composition Test (CCT) is effective for the early diagnosis of MCI. A total of 10...

(This article belongs to the Section Mental Health)
  • Article
  • Open Access
1 Citations
2,092 Views
12 Pages

Is the Postoperative Outcome after Intraarticular Distal Radius Fracture Influenced by Age and Gender? A PROM Study

  • Francesca Von Matthey,
  • Johannes Rüdiger Rammensee,
  • Peter Biberthaler and
  • Helen Abel

2 February 2023

Background: Although the most common fracture of the human body, so far, only few data concerning gender-specific outcomes after distal radius fracture exist. Typically, elderly women suffer from DRF due to a low-energy fall because of osteoporosis....

(This article belongs to the Section Orthopedics)
  • Perspective
  • Open Access
12 Citations
7,217 Views
14 Pages

2 February 2023

Long COVID, the postviral disorder caused by COVID-19, is expected to become one of the leading causes of disability in Europe. The cognitive consequences of long COVID have been described as “brain fog” and characterized by anxiety and d...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
22 Citations
3,473 Views
14 Pages

Large-Scale Genetic Correlation Analysis between Spondyloarthritis and Human Blood Metabolites

  • Mingyi Yang,
  • Jiawen Xu,
  • Feng Zhang,
  • Pan Luo,
  • Ke Xu,
  • Ruoyang Feng and
  • Peng Xu

2 February 2023

The aim was to study the genetic correlation and causal relationship between spondyloarthritis (SpA) and blood metabolites based on the large-scale genome-wide association study (GWAS) summary data. The GWAS summary data (3966 SpA and 448,298 control...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
8 Citations
2,532 Views
14 Pages

Paraoxonase 1 and Chronic Kidney Disease: A Meta-Analysis

  • Jun Watanabe,
  • Kazuhiko Kotani and
  • Alejandro Gugliucci

2 February 2023

Oxidative stress is known to be associated with the pathophysiology of chronic kidney disease (CKD). Paraoxonase 1 (PON1) is an antioxidant enzyme that has been proposed as a biomarker for CKD. While several studies have reported an association betwe...

(This article belongs to the Section Endocrinology & Metabolism)
  • Article
  • Open Access
10 Citations
4,160 Views
9 Pages

Influence of Ascorbic Acid as a Growth and Differentiation Factor on Dental Stem Cells Used in Regenerative Endodontic Therapies

  • Antje Diederich,
  • Hanna Juliane Fründ,
  • Bogusz Trojanowicz,
  • Alexander Navarrete Santos,
  • Anh Duc Nguyen,
  • Cuong Hoang-Vu and
  • Christian Ralf Gernhardt

2 February 2023

Background: Vitamin C is one of the major extracellular nonenzymatic antioxidants involved in the biosynthesis of collagen. It promotes the growth of fibroblasts, wound healing processes, and enhances the survival and differentiation of osteoblasts....

(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Endodontic Diseases)

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J. Clin. Med. - ISSN 2077-0383