Effect of Left Atrial Pulmonary Vein Angiography on Safety and Efficacy for High-Power, Short-Duration Pulmonary Vein Isolation in Patients with Atrial Fibrillation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ablation Procedure
2.2. Pulmonary Vein Angiography
2.3. Follow-Up
2.4. Endpoint
2.5. Statistical Analysis
3. Results
3.1. Baseline Characteristics
3.2. Procedural Data
3.3. Complications
3.4. Clinical Outcome
4. Discussion
4.1. Procedural Data
4.2. Complications
4.3. Clinical Outcome
4.4. Other Forms of Preprocedural PV Imaging
4.5. Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Angiography + (n = 67) | Angiography − (n = 72) | p-Value | |
---|---|---|---|
Age (years) | 66.09 ± 10.54 | 66.40 ± 12.72 | 0.48 |
Male, n (%) | 48 (71.64%) | 39 (53.42%) | 0.04 * |
BMI (kg/m2) | 28.31 ± 5.23 | 28.41 ± 5.17 | 1.00 |
Paroxysmal AF, n (%) | 21 (31.34%) | 29 (40.28%) | 0.29 |
CHA2DS2-VASc score | 2.46 ± 1.40 | 2.42 ± 1.47 | 0.87 |
LV ejection fraction % | 55.23 ± 12.50 | 57.36 ± 9.28 | 0.58 |
LA diameter, mm | 46.88 ± 8.86 | 46.41 ± 8.40 | 0.87 |
Atrial fibrosis % | 23.23 ± 26.81 | 18.92 ± 25.21 | 0.12 |
PV common ostium | 4 (5.97%) | 8 (11.11%) | 0.37 |
Additional PV | 9 (13.43%) | 15 (20.83%) | 0.27 |
Chronic kidney disease, n (%) | 12 (17.91%) | 14 (19.44%) | 0.83 |
Coronary artery disease, n (%) | 17 (25.37%) | 16 (22.22%) | 0.69 |
Hypertension, n (%) | 41 (61.19%) | 46 (63.89%) | 0.86 |
Diabetes, n (%) | 8 (11.94%) | 13 (18.06%) | 0.35 |
Prior stroke/TIA, n (%) | 6 (8.96%) | 1 (1.39%) | 0.06 |
Angiography + (n = 67) | Angiography − (n = 72) | p-Value | |
---|---|---|---|
PV entrance and exit block | 67 (100%) | 72 (100%) | 1.00 |
Additional ablations (substrate and/or CTI) | 13 (19.4%) | 9 (12.5%) | 0.35 |
Procedural duration (min) | 111.8 ± 23.65 | 117.7 ± 27.60 | 0.18 |
Dose area product (cGy*cm2) | 1574 ± 1125 | 976.1 ± 506.9 | 0.01 * |
Fluoroscopy time (min) | 13.9 ± 6.59 | 14.56 ± 6.36 | 0.45 |
Contrast agent (ml) | 37.75 ± 5.92 | 7.17 ± 1.74 | <0.01 * |
Major complication | 0 (0%) | 0 (0%) | 1.00 |
Minor complication | 3 (4.41%) | 3 (4.47%) | 1.00 |
Recurrence of AF in the first year after PVI | 20 (29.85%) | 17 (23.61%) | 0.45 |
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Weyand, S.; Adam, V.; Beuter, M.; Hanger, S.; Heinzmann, D.; Schrezenmeier, W.; Seizer, P. Effect of Left Atrial Pulmonary Vein Angiography on Safety and Efficacy for High-Power, Short-Duration Pulmonary Vein Isolation in Patients with Atrial Fibrillation. J. Clin. Med. 2023, 12, 1094. https://doi.org/10.3390/jcm12031094
Weyand S, Adam V, Beuter M, Hanger S, Heinzmann D, Schrezenmeier W, Seizer P. Effect of Left Atrial Pulmonary Vein Angiography on Safety and Efficacy for High-Power, Short-Duration Pulmonary Vein Isolation in Patients with Atrial Fibrillation. Journal of Clinical Medicine. 2023; 12(3):1094. https://doi.org/10.3390/jcm12031094
Chicago/Turabian StyleWeyand, Sebastian, Viola Adam, Matthias Beuter, Simon Hanger, David Heinzmann, Willibald Schrezenmeier, and Peter Seizer. 2023. "Effect of Left Atrial Pulmonary Vein Angiography on Safety and Efficacy for High-Power, Short-Duration Pulmonary Vein Isolation in Patients with Atrial Fibrillation" Journal of Clinical Medicine 12, no. 3: 1094. https://doi.org/10.3390/jcm12031094
APA StyleWeyand, S., Adam, V., Beuter, M., Hanger, S., Heinzmann, D., Schrezenmeier, W., & Seizer, P. (2023). Effect of Left Atrial Pulmonary Vein Angiography on Safety and Efficacy for High-Power, Short-Duration Pulmonary Vein Isolation in Patients with Atrial Fibrillation. Journal of Clinical Medicine, 12(3), 1094. https://doi.org/10.3390/jcm12031094