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Most Cited

  • Article
  • Open Access
289 Citations
14,966 Views
14 Pages

31 January 2023

Background and aim: Chronic low-grade inflammation is associated with various health outcomes, including cardiovascular diseases (CVDs) and cancers. Systemic immune inflammation index (SII) and system inflammation response index (SIRI) have lately be...

  • Review
  • Open Access
251 Citations
76,120 Views
24 Pages

Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics

  • Samradhi Singh,
  • Namrata Pal,
  • Swasti Shubham,
  • Devojit Kumar Sarma,
  • Vinod Verma,
  • Francesco Marotta and
  • Manoj Kumar

11 February 2023

Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, typically characterized by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries. Lifestyle or diet, environmental pollutants, genetics, gut dysbi...

  • Perspective
  • Open Access
159 Citations
50,960 Views
17 Pages

Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Glp-1 Receptor Agonists: A Multidisciplinary Expert Consensus

  • Juan J. Gorgojo-Martínez,
  • Pedro Mezquita-Raya,
  • Juana Carretero-Gómez,
  • Almudena Castro,
  • Ana Cebrián-Cuenca,
  • Alejandra de Torres-Sánchez,
  • María Dolores García-de-Lucas,
  • Julio Núñez,
  • Juan Carlos Obaya and
  • María José Soler
  • + 2 authors

24 December 2022

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are indicated in type 2 diabetes and obesity for their high efficacy in controlling glycaemia and inducing body weight loss, respectively. Patients may develop gastrointestinal adverse events (GI...

  • Systematic Review
  • Open Access
158 Citations
22,267 Views
13 Pages

A Meta-Analysis of the Global Prevalence of Temporomandibular Disorders

  • Grzegorz Zieliński,
  • Beata Pająk-Zielińska and
  • Michał Ginszt

28 February 2024

Background: This meta-analysis aims to evaluate the proportion of people with TMDs in different studies, considering factors such as geographical region, patient age, and sample size. Methods: The search yielded 6984 articles on the incidence of TMDs...

  • Review
  • Open Access
155 Citations
10,133 Views
24 Pages

Age, Sex and Previous Comorbidities as Risk Factors Not Associated with SARS-CoV-2 Infection for Long COVID-19: A Systematic Review and Meta-Analysis

  • Kin Israel Notarte,
  • Maria Helena Santos de Oliveira,
  • Princess Juneire Peligro,
  • Jacqueline Veronica Velasco,
  • Imee Macaranas,
  • Abbygail Therese Ver,
  • Flos Carmeli Pangilinan,
  • Adriel Pastrana,
  • Nathaniel Goldrich and
  • David Kavteladze
  • + 5 authors

9 December 2022

Identification of predictors of long COVID-19 is essential for managing healthcare plans of patients. This systematic literature review and meta-analysis aimed to identify risk factors not associated with Severe Acute Respiratory Syndrome Coronavirus...

  • Review
  • Open Access
143 Citations
131,558 Views
23 Pages

2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department

  • Matteo Guarino,
  • Benedetta Perna,
  • Alice Eleonora Cesaro,
  • Martina Maritati,
  • Michele Domenico Spampinato,
  • Carlo Contini and
  • Roberto De Giorgio

28 April 2023

Background: Sepsis/septic shock is a life-threatening and time-dependent condition that requires timely management to reduce mortality. This review aims to update physicians with regard to the main pillars of treatment for this insidious condition. M...

  • Review
  • Open Access
141 Citations
24,991 Views
33 Pages

Artificial Intelligence in Dermatology Image Analysis: Current Developments and Future Trends

  • Zhouxiao Li,
  • Konstantin Christoph Koban,
  • Thilo Ludwig Schenck,
  • Riccardo Enzo Giunta,
  • Qingfeng Li and
  • Yangbai Sun

18 November 2022

Background: Thanks to the rapid development of computer-based systems and deep-learning-based algorithms, artificial intelligence (AI) has long been integrated into the healthcare field. AI is also particularly helpful in image recognition, surgical...

  • Review
  • Open Access
136 Citations
34,269 Views
28 Pages

Understanding and Fostering Mental Health and Well-Being among University Faculty: A Narrative Review

  • Dalal Hammoudi Halat,
  • Abderrezzaq Soltani,
  • Roua Dalli,
  • Lama Alsarraj and
  • Ahmed Malki

30 June 2023

In recent years, there has been increasing recognition of mental health concerns in academia, with stress, burnout, anxiety, and depression being reported among faculty members. The demanding work environment, the need to balance personal and profess...

  • Review
  • Open Access
118 Citations
15,669 Views
21 Pages

Past, Present and (Foreseeable) Future of Biological Anti-TNF Alpha Therapy

  • Gian Marco Leone,
  • Katia Mangano,
  • Maria Cristina Petralia,
  • Ferdinando Nicoletti and
  • Paolo Fagone

17 February 2023

Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and used in the clinical treatment of autoimmune disorders. Currently, five a...

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license