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Journal of Clinical Medicine, Volume 12, Issue 3

2023 February-1 - 513 articles

Cover Story: Pulmonary vein isolation (PVI) is increasingly important for the treatment of the ever-increasing number of patients with atrial fibrillation. Therefore, continuous improvement of the PVI workflow is urgently needed. The aim of this study was to evaluate the impact of omitting pulmonary vein (PV) angiography before ablation on the safety and efficacy of PVI. For this purpose, patients who received PVI with PV angiography were compared with patients who received PVI without PV angiography. Apart from the fact that the fluoroscopy dose and the amount of contrast agent were significantly reduced when PV angiography was omitted, there were no differences between the groups. Thus, it can be useful to avoid PV angiography especially in young patients and those with chronic kidney disease. View this paper
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Articles (513)

  • Article
  • Open Access
17 Citations
3,541 Views
11 Pages

Prognostic Role of Monocyte Distribution Width, CRP, Procalcitonin and Lactate as Sepsis Biomarkers in Critically Ill COVID-19 Patients

  • Dejana Bajić,
  • Jovan Matijašević,
  • Ljiljana Andrijević,
  • Bojan Zarić,
  • Mladena Lalić-Popović,
  • Ilija Andrijević,
  • Nemanja Todorović,
  • Andrea Mihajlović,
  • Borislav Tapavički and
  • Jelena Ostojić

2 February 2023

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic and one group of patients has developed a severe form of COVID-19 pneumonia with an urgent need for hospitalization and intensive care unit (ICU) admission. The...

(This article belongs to the Section Intensive Care)
  • Article
  • Open Access
3 Citations
3,743 Views
9 Pages

2 February 2023

This article compares the visual performance of a violet light-filtering colored lens (ZCB00V) and blue light-filtering intraocular lens (IOL; SN60WF) before and after modifying the manufacturing process for glistening suppression. In this retrospect...

(This article belongs to the Special Issue Ophthalmic Optics and Visual Function—Part II)
  • Article
  • Open Access
6 Citations
3,505 Views
14 Pages

Heart Rate Asymmetry in Healthy Children

  • Dominika Zalas,
  • Waldemar Bobkowski,
  • Jarosław Piskorski and
  • Przemysław Guzik

2 February 2023

Heart rate asymmetry (HRA) is a physiological phenomenon characterized by an unequal contribution of heart rate decelerations and accelerations to different heart rate variability (HRV) features. While HRA has been demonstrated in adults’ ECGs...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
7 Citations
2,533 Views
20 Pages

Prediction of Surgical Approach in Mitral Valve Disease by XGBoost Algorithm Based on Echocardiographic Features

  • Xiaoxuan Lin,
  • Lixin Chen,
  • Defu Zhang,
  • Shuyu Luo,
  • Yuanyuan Sheng,
  • Xiaohua Liu,
  • Qian Liu,
  • Jian Li,
  • Bobo Shi and
  • Yingying Liu
  • + 8 authors

2 February 2023

In this study, we aimed to develop a prediction model to assist surgeons in choosing an appropriate surgical approach for mitral valve disease patients. We retrospectively analyzed a total of 143 patients who underwent surgery for mitral valve diseas...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
22 Citations
3,837 Views
13 Pages

The Effect of Transcutaneous Electrical Acupoint Stimulation on High-Risk Patients with PONV Undergoing Laparoscopic Gynecologic Surgery: A Randomized Controlled Trial

  • Jiazhu Qin,
  • Xiaoxiao Ye,
  • Changzhou Ye,
  • Xuliang Huang,
  • Huanhuan Sun,
  • Xinyu Zhao,
  • Yao Tong,
  • Manala Mazomba and
  • Yunchang Mo

2 February 2023

Background: Postoperative nausea and vomiting (PONV) is one of the most common complications after general anesthesia. The traditional comprehensive management of PONV usually uses one or two drugs, but this regimen fails to meet the requirements of...

(This article belongs to the Section Anesthesiology)
  • Case Report
  • Open Access
17 Citations
5,538 Views
9 Pages

2 February 2023

Atopic dermatitis is a chronic inflammatory intensively pruritic skin disease. Patients with moderate-to-severe atopic dermatitis or with difficult-to-treat areas are candidates for systemic therapy, especially when topical therapy is inadequate. Cur...

(This article belongs to the Special Issue Atopic Dermatitis: Research and Clinical Updates and Perspectives)
  • Article
  • Open Access
31 Citations
5,850 Views
11 Pages

Clinical Distribution and Drug Resistance of Pseudomonas aeruginosa in Guangzhou, China from 2017 to 2021

  • Jingwen Lyu,
  • Huimin Chen,
  • Jinwei Bao,
  • Suling Liu,
  • Yiling Chen,
  • Xuxia Cui,
  • Caixia Guo,
  • Bing Gu and
  • Lu Li

2 February 2023

The aim of the current study was to analyse the distribution of antimicrobial drug resistance (AMR) among Pseudomonas aeruginosa (P. aeruginosa, PA) isolates from Guangdong Provincial People’s Hospital (GDPH) from 2017 to 2021, and the impact o...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Review
  • Open Access
11 Citations
5,027 Views
18 Pages

A Review of Modern Imaging Landscape for Prostate Cancer: A Comprehensive Clinical Guide

  • Paul Gravestock,
  • Bhaskar Kumar Somani,
  • Theodoros Tokas and
  • Bhavan Prasad Rai

2 February 2023

The development of prostate cancer imaging is rapidly evolving, with many changes to the way patients are diagnosed, staged, and monitored for recurrence following treatment. New developments, including the potential role of imaging in screening and...

(This article belongs to the Special Issue Prostate Cancer: Recent Advances in Diagnostics and Treatment Planning)
  • Review
  • Open Access
23 Citations
8,304 Views
14 Pages

Old and New Precipitants in Hepatic Encephalopathy: A New Look at a Field in Continuous Evolution

  • Daniele Bellafante,
  • Stefania Gioia,
  • Jessica Faccioli,
  • Oliviero Riggio,
  • Lorenzo Ridola and
  • Silvia Nardelli

2 February 2023

Hepatic encephalopathy (HE) is a common complication in patients with advanced liver disease. It is a brain dysfunction characterized by neurological and psychiatric symptoms that significantly affects quality of life, morbidity and mortality of pati...

(This article belongs to the Topic Recent Advances in Hepatology)
  • Article
  • Open Access
13 Citations
3,307 Views
8 Pages

Trends in Gynecologic Carcinosarcoma Based on Analysis of the Surveillance Epidemiology End Result (SEER) Database

  • Joo Won Lee,
  • Yung-Taek Ouh,
  • Ha Kyun Chang,
  • Kyung-Jin Min,
  • Sanghoon Lee,
  • Jin-Hwa Hong,
  • Jae-Yun Song,
  • Jae-Kwan Lee and
  • Nak Woo Lee

2 February 2023

Carcinosarcomas (malignant mixed Mullerian tumors) of a female genital organ are rare tumors associated with a poor survival. The purpose of this study was to identify site-specific differences in the incidence and prognosis in carcinosarcomas origin...

(This article belongs to the Section Obstetrics & Gynecology)
  • Review
  • Open Access
21 Citations
8,626 Views
11 Pages

Ultrasound in Sepsis and Septic Shock—From Diagnosis to Treatment

  • Gianluca Tullo,
  • Marcello Candelli,
  • Irene Gasparrini,
  • Sara Micci and
  • Francesco Franceschi

2 February 2023

Sepsis and septic shock are among the leading causes of in-hospital mortality worldwide, causing a considerable burden for healthcare. The early identification of sepsis as well as the individuation of the septic focus is pivotal, followed by the pro...

(This article belongs to the Special Issue Ultrasound Technology in Intensive Care: Current and Emerging Treatment)
  • Opinion
  • Open Access
9 Citations
3,323 Views
9 Pages

Cardiac Contractility Modulation Therapy in Patients with Amyloid Cardiomyopathy and Heart Failure, Case Report, Review of the Biophysics of CCM Function, and AMY-CCM Registry Presentation

  • Procolo Marchese,
  • Francesca Gennaro,
  • Giovanni Mazzotta,
  • Claudia Acciarri,
  • Stenio Amabili,
  • Carlo Bonanni,
  • Antonella D’Antonio,
  • Domenico Delfino,
  • Luca Di Vito and
  • Pierfrancesco Grossi
  • + 5 authors

2 February 2023

Cardiac amyloidosis may result in an aggressive form of heart failure (HF). Cardiac contractility modulation (CCM) has been shown to be a concrete therapeutic option in patients with symptomatic HF, but there is no evidence of its application in pati...

(This article belongs to the Special Issue New Advances in Pharmacologic and Non-pharmacologic Therapy in Heart Failure and Heart Transplant)
  • Article
  • Open Access
18 Citations
3,594 Views
14 Pages

Stereotactic MR-Guided Radiotherapy for Liver Metastases: First Results of the Montpellier Prospective Registry Study

  • Karl Bordeau,
  • Morgan Michalet,
  • Aïcha Keskes,
  • Simon Valdenaire,
  • Pierre Debuire,
  • Marie Cantaloube,
  • Morgane Cabaillé,
  • William Jacot,
  • Roxana Draghici and
  • Olivier Riou
  • + 12 authors

2 February 2023

Liver stereotactic body radiotherapy (SBRT) is a local treatment that provides good local control and low toxicity. We present the first clinical results from our prospective registry of stereotactic MR-guided radiotherapy (MRgRT) for liver metastase...

(This article belongs to the Section Nuclear Medicine & Radiology)
  • Article
  • Open Access
10 Citations
6,097 Views
19 Pages

Impacts of COVID-19 Pandemic on Sleep Quality Evaluated by Wrist Actigraphy: A Systematic Review

  • Luiz Felipe Ferreira-Souza,
  • Marize Julianelli-Peçanha,
  • Ana Carolina Coelho-Oliveira,
  • Christianne Martins Corrêa da Silva Bahia,
  • Laisa Liane Paineiras-Domingos,
  • Aline Reis-Silva,
  • Márcia Cristina Moura-Fernandes,
  • Luiza Carla Trindade-Gusmão,
  • Redha Taiar and
  • Mario Bernardo-Filho
  • + 2 authors

2 February 2023

COVID-19 has probably contributed as a risk factor for sleep disturbance. Actigraphy has been used to evaluate sleep complaints in self-isolated populations and frontline doctors during the COVID-19 pandemic. This systematic review aims to summarize...

(This article belongs to the Section Sports Medicine)
  • Article
  • Open Access
14 Citations
8,181 Views
9 Pages

The Use of Ultrasonic Bone Scalpel (UBS) in Unilateral Biportal Endoscopic Spine Surgery (UBESS): Technical Notes and Outcomes

  • Sung Huang Laurent Tsai,
  • Chia-Wei Chang,
  • Tung-Yi Lin,
  • Ying-Chih Wang,
  • Chak-Bor Wong,
  • Abdul Karim Ghaith,
  • Mohammed Ali Alvi,
  • Tsai-Sheng Fu and
  • Mohamad Bydon

2 February 2023

Study Design: Case Series and Technical Note, Objective: UBS has been extensively used in open surgery. However, the use of UBS during UBESS has not been reported in the literature. The aim of this study was to describe a new spinal surgical techniqu...

(This article belongs to the Special Issue Advances in Minimally Invasive Spine Surgery)
  • Article
  • Open Access
13 Citations
3,764 Views
12 Pages

Clinical Predictors and Prognosis of Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) without ST-Segment Elevation in Older Adults

  • Ana Gabaldon-Perez,
  • Clara Bonanad,
  • Sergio Garcia-Blas,
  • Víctor Marcos-Garcés,
  • Jessika Gonzalez D’Gregorio,
  • Agustín Fernandez-Cisnal,
  • Ernesto Valero,
  • Gema Minana,
  • Héctor Merenciano-González and
  • Juan Sanchis
  • + 3 authors

2 February 2023

A non-neglectable percentage of patients with non-ST elevation myocardial infarction (NSTEMI) show non-obstructive coronary arteries (MINOCA). Specific data in older patients are scarce. We aimed to identify the clinical predictors of MINOCA in older...

(This article belongs to the Special Issue Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA): Current Status, Challenges and Future Directions)
  • Article
  • Open Access
14 Citations
3,726 Views
9 Pages

Prospective Assessment of Cerebral Microbleeds with Low-Field Magnetic Resonance Imaging (0.55 Tesla MRI)

  • Thilo Rusche,
  • Hanns-Christian Breit,
  • Michael Bach,
  • Jakob Wasserthal,
  • Julian Gehweiler,
  • Sebastian Manneck,
  • Johanna M. Lieb,
  • Gian Marco De Marchis,
  • Marios Psychogios and
  • Peter B. Sporns

2 February 2023

Purpose: Accurate detection of cerebral microbleeds (CMBs) on susceptibility-weighted (SWI) magnetic resonance imaging (MRI) is crucial for the characterization of many neurological diseases. Low-field MRI offers greater access at lower costs and low...

(This article belongs to the Special Issue New Advances in Diagnostic Radiology of Ischemic Stroke)
  • Article
  • Open Access
6 Citations
2,805 Views
11 Pages

Actigraphic Sensors Describe Stroke Severity in the Acute Phase: Implementing Multi-Parametric Monitoring in Stroke Unit

  • Giuseppe Reale,
  • Chiara Iacovelli,
  • Marco Rabuffetti,
  • Paolo Manganotti,
  • Lucio Marinelli,
  • Simona Sacco,
  • Giovanni Furlanis,
  • Miloš Ajčević,
  • Aurelia Zauli and
  • Pietro Caliandro
  • + 8 authors

2 February 2023

Actigraphy is a tool used to describe limb motor activity. Some actigraphic parameters, namely Motor Activity (MA) and Asymmetry Index (AR), correlate with stroke severity. However, a long-lasting actigraphic monitoring was never performed previously...

(This article belongs to the Topic Diagnosis and Management of Acute Ischemic Stroke)
  • Review
  • Open Access
36 Citations
10,559 Views
15 Pages

1 February 2023

Psoriasis is a chronic inflammatory skin disease with a high prevalence of cardiovascular disease (CVD), obesity, dyslipidemia, hypertension, diabetes mellitus, and metabolic syndrome. Among them, CVD is the most common cause of morbidity and mortali...

(This article belongs to the Special Issue Psoriasis and Psoriatic Arthritis: How to Treat in the Era of Biologics and Small Molecule Inhibitors: 2nd Edition)
  • Article
  • Open Access
13 Citations
3,530 Views
14 Pages

miR-197-3p Promotes Osteosarcoma Stemness and Chemoresistance by Inhibiting SPOPL

  • Jingyong Zhang,
  • Shubao Wang,
  • Yang Bai,
  • Aasi Mohammad Ali,
  • Jiewen Deng,
  • Yushi Chen,
  • Yonghui Fu and
  • Ming He

1 February 2023

First-line treatment for osteosarcoma includes chemotherapy and surgery. However, the five-year survival rate of refractory osteosarcoma remains unsatisfactory. Osteosarcoma cancer stem cells, possessing stemness and chemoresistance, are one of the c...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
90 Citations
19,082 Views
11 Pages

Tinnitus and Its Relation to Depression, Anxiety, and Stress—A Population-Based Cohort Study

  • Berit Hackenberg,
  • Julia Döge,
  • Karoline O’Brien,
  • Andrea Bohnert,
  • Karl J. Lackner,
  • Manfred E. Beutel,
  • Matthias Michal,
  • Thomas Münzel,
  • Philipp S. Wild and
  • Katharina Bahr
  • + 4 authors

1 February 2023

Tinnitus is a common symptom reported in otolaryngologic practice. Although the pathophysiology of tinnitus has not been fully understood, clinical studies suggest that psychological symptoms of depression, anxiety, and somatization are increased in...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
2 Citations
2,849 Views
13 Pages

Predict the Effects of Dolutegravir (DTG) Plus Lamivudine (3TC) on Immunological Responses in People Living with HIV (PLWHIV)

  • Jesús Troya,
  • Roberto Pedrero-Tomé,
  • Luis Buzón,
  • Carlos Dueñas and
  • on behalf of the SPADE Study Group

1 February 2023

Background: Immune recovery in people living with HIV (PLWHIV) is a residual aspect of antiretroviral treatment (ART) in most patients, but in a non-negligible proportion of them, the CD4+ lymphocytes count, or CD4/CD8 ratio remains suboptimal. Metho...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
1 Citations
2,248 Views
7 Pages

Influence of Prostate Cancer on Thulium Vapoenucleation of the Prostate—A Multicentre Analysis

  • Tobias Lamersdorf,
  • Christopher Netsch,
  • Benedikt Becker,
  • Christian Wülfing,
  • Petra Anheuser,
  • Oliver Engel,
  • Andreas J. Gross and
  • Clemens Mathias Rosenbaum

1 February 2023

Purpose: Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are common in elderly men. Data on the laser-based surgery known as thulium vapoenucleation of the prostate (ThuVEP) in PCa patients are rare. Our objective was to analyse the feas...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
15 Citations
5,465 Views
12 Pages

Efficacy and Treatment Satisfaction of Different Systemic Therapies in Children and Adolescents with Moderate-to-Severe Atopic Dermatitis: A Real-World Study

  • Sebastian Kiefer,
  • Anke König,
  • Viviane Gerger,
  • Christine Rummenigge,
  • Anne Christine Müller,
  • Thomas Jung,
  • Alexandra Frank,
  • Georgios Tassopoulos,
  • Emilie Laurent and
  • Andreas Pinter
  • + 1 author

1 February 2023

For the treatment of moderate-to-severe atopic dermatitis in children and adolescents, the monoclonal antibody dupilumab and the selective JAK-1 inhibitor upadacitinib are two modern systemic therapies approved for long-term treatment. Both drugs hav...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
25 Citations
5,462 Views
11 Pages

Serum KL-6 as a Biomarker of Progression at Any Time in Fibrotic Interstitial Lung Disease

  • Lutz B. Jehn,
  • Ulrich Costabel,
  • Eda Boerner,
  • Julia Wälscher,
  • Dirk Theegarten,
  • Christian Taube and
  • Francesco Bonella

1 February 2023

The development of a progressive phenotype of interstitial lung disease (ILD) is still unpredictable. Whereas tools to predict mortality in ILD exist, scores to predict disease progression are missing. The aim of this study was to investigate whether...

(This article belongs to the Section Respiratory Medicine)
  • Review
  • Open Access
9 Citations
3,561 Views
17 Pages

Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions

  • Mariachiara Zuccarini,
  • Letizia Pruccoli,
  • Martina Balducci,
  • Patricia Giuliani,
  • Francesco Caciagli,
  • Renata Ciccarelli and
  • Patrizia Di Iorio

1 February 2023

The production of reactive oxygen species (ROS) in the brain is homeostatically controlled and contributes to normal neural functions. Inefficiency of control mechanisms in brain aging or pathological conditions leads to ROS overproduction with oxida...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
9 Citations
2,372 Views
12 Pages

Safety and Efficacy of Surgery for Metastatic Tumor to the Pancreas: A Single-Center Experience

  • Lucia Moletta,
  • Alberto Friziero,
  • Simone Serafini,
  • Valeria Grillo,
  • Elisa Sefora Pierobon,
  • Giovanni Capovilla,
  • Michele Valmasoni and
  • Cosimo Sperti

1 February 2023

Pancreatic metastases from other neoplasms are rare. The role of surgery for this clinical entity is unclear. The aim of this study was to investigate the role of resection in patients with pancreatic secondary lesions. We observed 44 patients with p...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
9 Citations
3,197 Views
10 Pages

One-Stage Immediate Alloplastic Breast Reconstruction in Large and Ptotic Breasts: An Institutional Algorithm

  • Silvia Rampazzo,
  • Noemi Spissu,
  • Michela Pinna,
  • Germana A. M. Sini,
  • Emilio Trignano,
  • Rita Nonnis,
  • Claudia Sanna,
  • Manuela Rodio,
  • Matilde Tettamanzi and
  • Corrado Rubino

1 February 2023

Immediate implant-based breast reconstruction in patients with large and ptotic breasts may be challenging due to skin redundancy. The use of a reduction mammoplasty pattern for the mastectomy skin excision has proven to be a reliable option for thes...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
8 Citations
13,842 Views
13 Pages

1 February 2023

Facial skin aging is an important psychophysical and social concern, especially in women. We compared facial parameters reflecting aging of the skin in 1999 and 2010 in 86 female volunteers. Then, all subjects applied three Galactomyces ferment filtr...

(This article belongs to the Special Issue 10th Anniversary of JCM – New Era in Dermatology)
  • Article
  • Open Access
8 Citations
4,128 Views
11 Pages

1 February 2023

Currently, there is uncertainty about the predictive factors for metastatic epidural spinal cord compression (MESCC) and consecutive symptomatology in tumor patients. Prognostic algorithms for identifying patients at risk for paralysis are missing. T...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
31 Citations
4,587 Views
11 Pages

1 February 2023

Objective: We aimed to develop and validate a predictive machine learning (ML) model for cardiac surgery associated with acute kidney injury (CSA-AKI) based on a multicenter randomized control trial (RCT) and a Medical Information Mart for Intensive...

(This article belongs to the Section Anesthesiology)
  • Review
  • Open Access
13 Citations
5,758 Views
14 Pages

Electric Cardioversion vs. Pharmacological with or without Electric Cardioversion for Stable New-Onset Atrial Fibrillation: A Systematic Review and Meta-Analysis

  • Paritosh Prasai,
  • Dhan Bahadur Shrestha,
  • Eltaib Saad,
  • Angkawipa Trongtorsak,
  • Aarya Adhikari,
  • Suman Gaire,
  • Prakash Raj Oli,
  • Jurgen Shtembari,
  • Pabitra Adhikari and
  • Ghanshyam Shantha
  • + 3 authors

1 February 2023

Background: There is no clear consensus on the preference for pharmacological cardioversion (PC) in comparison to electric cardioversion (EC) for hemodynamically stable new-onset atrial fibrillation (NOAF) patients presenting to the emergency departm...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
10 Citations
8,471 Views
12 Pages

Effect of Hypochlorous Acid on Blepharitis through Ultrasonic Atomization: A Randomized Clinical Trial

  • Hong Zhang,
  • Yuqing Wu,
  • Xichen Wan,
  • Yan Shen,
  • Qihua Le,
  • Pei Yang,
  • Shuyun Zhou,
  • Xujiao Zhou,
  • Feng Zhou and
  • Jiaxu Hong
  • + 1 author

1 February 2023

Purpose: To evaluate the efficacy and safety of eyelid hygiene using topical 0.01% hypochlorous acid (HOCL) through ultrasonic atomization after 2 weeks in patients with blepharitis. Design: Randomized controlled trial. Methods: Patients with blephar...

(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Ocular Surface Diseases)
  • Article
  • Open Access
7 Citations
2,725 Views
9 Pages

1 February 2023

Closed reduction and percutaneous internal fixation (CRPIF) for acetabular fractures was introduced as a less invasive alternative to open reduction and internal fixation (ORIF) for moderately displaced fractures. Currently, comparisons of ORIF and C...

(This article belongs to the Special Issue Fractures of the Pelvis and Acetabulum: Novel Insights in Diagnostics and Treatment)
  • Article
  • Open Access
2 Citations
7,827 Views
13 Pages

1 February 2023

The optimal number of examined lymph nodes (ELNs) for gastric signet ring cell carcinoma recommended by National Comprehensive Cancer Network guidelines remains unclear. This study aimed to determine the optimal number of ELNs and investigate its pro...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
5 Citations
2,656 Views
10 Pages

1 February 2023

This study aims to evaluate the efficacy of anti-factor Xa activity (aFXa) in predicting ecchymosis after total knee arthroplasty (TKA). One hundred and two unilateral primary TKA patients were recruited consecutively in this prospective observationa...

(This article belongs to the Section Orthopedics)
  • Review
  • Open Access
27 Citations
8,831 Views
12 Pages

Risk of New-Onset Diabetes Mellitus as a Post-COVID-19 Condition and Possible Mechanisms: A Scoping Review

  • Prabal Chourasia,
  • Lokesh Goyal,
  • Dhruv Kansal,
  • Sasmit Roy,
  • Rohit Singh,
  • Indrajeet Mahata,
  • Abu Baker Sheikh and
  • Rahul Shekhar

1 February 2023

Long-term effects of COVID-19 are becoming more apparent even as the severity of acute infection is decreasing due to vaccinations and treatment. In this scoping review, we explored the current literature for the relationship between COVID-19 infecti...

(This article belongs to the Section Epidemiology & Public Health)
  • Systematic Review
  • Open Access
4 Citations
3,493 Views
14 Pages

A Practical Approach to Systemic Mastocytosis Complications in Cardiac Surgery: A Case Report and Systematic Review of the Literature

  • Mathieu N. Suleiman,
  • Valeska Brueckl,
  • Jörg Fechner,
  • Ann-Sophie Kaemmerer,
  • Florian Wilk,
  • Michael Weyand and
  • Frank Harig

1 February 2023

(1) Background: Systemic mastocytosis is a rare, non-curable disease with potential life-threatening complications in patients receiving cardiac surgery. (2) Methods: This systematic review of the literature was prompted by the case of a life-threate...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
8 Citations
3,126 Views
9 Pages

Clinical Evaluation of the Efficacy of Femtosecond Laser-Assisted Anterior Lamellar Keratoplasty

  • Adam Wylęgała,
  • Anna M. Roszkowska,
  • Joanna Kokot,
  • Dariusz Dobrowolski and
  • Edward Wylęgała

1 February 2023

Background: To evaluate the clinical outcome, efficacy, and safety of femtosecond laser-assisted anterior lamellar keratoplasty. Material and Methods: In this prospective study, 21 males and 10 females aged from 15 to 62 years (mean 38.5) with differ...

(This article belongs to the Special Issue Refractive Surgery—Where Are We Now?)
  • Article
  • Open Access
8 Citations
3,634 Views
9 Pages

Endovascular Thrombectomy with or without Intravenous Thrombolysis for Anterior Circulation Large Vessel Occlusion in the Imperial College London Thrombectomy Registry

  • Lucio D’Anna,
  • Matteo Foschi,
  • Michele Russo,
  • Tsering Dolkar,
  • Orsolya Vittay,
  • Luke Dixon,
  • Paul Bentley,
  • Zoe Brown,
  • Charles Hall and
  • Soma Banerjee
  • + 12 authors

1 February 2023

Background and purpose. Mechanical thrombectomy (MT) is the standard of care for eligible patients with a large vessel occlusion (LVO) acute ischemic stroke. Among patients undergoing MT there has been uncertainty regarding the role of intravenous th...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
7 Citations
4,014 Views
18 Pages

Can Measuring the ‘Dual Anchors of Aorta’ Enhance the Success Rate of TAVR?—A Single-Center Experience

  • Yang Chen,
  • Md Misbahul Ferdous,
  • Lakshme Kottu,
  • Jie Zhao,
  • Hong-Liang Zhang,
  • Mo-Yang Wang,
  • Guan-Nan Niu,
  • Qing-Rong Liu,
  • Zheng Zhou and
  • Yong-Jian Wu
  • + 9 authors

1 February 2023

Introduction: Chronic severe aortic regurgitation (AR) has a poor long-term prognosis, especially among old-age patients. Considering their advancing age, the surgical approach of aortic valve replacement may not always be the best alternative modali...

(This article belongs to the Section Vascular Medicine)
  • Article
  • Open Access
3 Citations
5,893 Views
18 Pages

An Exploratory Analysis on the 2D:4D Digit Ratio and Its Relationship with Social Responsiveness in Adults with Prader–Willi Syndrome

  • Sara Gámez,
  • Jesus Cobo,
  • Meritxell Fernández-Lafitte,
  • Ramón Coronas,
  • Isabel Parra,
  • Joan Carles Oliva,
  • Aida Àlvarez,
  • Susanna Esteba-Castillo,
  • Olga Giménez-Palop and
  • Assumpta Caixàs
  • + 2 authors

1 February 2023

Prader–Willi syndrome (PWS) is a genetic disorder produced by a lack of expression of paternally derived genes in the 15q11–13 region. Research has generally focused on its genetic and behavioral expression, but only a few studies have ex...

(This article belongs to the Special Issue Endocrinology and Metabolic Diseases: Prader-Willi Syndrome)
  • Systematic Review
  • Open Access
18 Citations
5,607 Views
13 Pages

1 February 2023

Beneficial off-target effects of the Bacillus Calmette-Guérin (BCG) vaccination might offer general protection from respiratory tract infections. We conducted a systematic review and meta-analysis of published randomized controlled trials (RCT...

(This article belongs to the Special Issue Vaccine against COVID-19: Current State of the Art and Future Perspectives)
  • Article
  • Open Access
2 Citations
2,973 Views
10 Pages

Greater Tuberosity Fractures after RTSA: A Matched Group Analysis

  • Farah Selman,
  • Philipp Kriechling,
  • Lukas Ernstbrunner,
  • Karl Wieser and
  • Paul Borbas

1 February 2023

Periprosthetic fractures, such as acromial and spine fractures, are known complications following implantation of reverse shoulder arthroplasty (RTSA). The entity of greater tuberosity fractures (GTF) has rarely been studied in the literature. The pu...

(This article belongs to the Special Issue Reverse Total Shoulder Arthroplasty for Proximal Humeral Fracture Sequelae: Outcome, Challenges and Designs)
  • Article
  • Open Access
24 Citations
4,329 Views
12 Pages

Intraoperative Low-Dose S-Ketamine Reduces Depressive Symptoms in Patients with Crohn’s Disease Undergoing Bowel Resection: A Randomized Controlled Trial

  • Zhen Zhang,
  • Wen-Hao Zhang,
  • Yin-Xiao Lu,
  • Bo-Xuan Lu,
  • Yi-Bo Wang,
  • Li-Ying Cui,
  • Hao Cheng,
  • Zhen-Yu Yuan,
  • Jie Zhang and
  • Qing Ji
  • + 2 authors

1 February 2023

Background: Patients with Crohn’s disease (CD) undergoing bowel resection often suffer from depression and acute pain, which severely impairs their recovery. We aimed to investigate the effects of S-ketamine preconditioning on postoperative dep...

(This article belongs to the Section Anesthesiology)
  • Review
  • Open Access
8 Citations
6,131 Views
12 Pages

Malaysian Society of Allergy and Immunology Consensus Statement on Sublingual Immunotherapy in Allergic Rhinitis

  • Baharudin Abdullah,
  • Ruby Pawankar,
  • Amir Hamzah Abdul Latiff,
  • Kent Chee Keen Woo,
  • Eike Wüstenberg,
  • Mohamad Azizul Fitri Khalid,
  • Yeoh Zhi Xiang,
  • Salina Husain,
  • Nurashikin Mohammad and
  • Norasnieda Md Shukri

1 February 2023

Allergic rhinitis (AR) is an IgE-mediated inflammatory disease of the upper airway. AR affects the patients’ quality of life, is a known risk factor for asthma and a socio-economic burden. Allergen-specific immunotherapy (AIT), comprising subli...

(This article belongs to the Special Issue Allergen Immunotherapy in Allergic Diseases)
  • Article
  • Open Access
5 Citations
5,677 Views
15 Pages

The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD): Changes in Preferred Treatment Strategies and Medications over 20 Years and Five Editions

  • Seung-Ho Jang,
  • Won-Myong Bahk,
  • Young Sup Woo,
  • Jeong Seok Seo,
  • Young-Min Park,
  • Won Kim,
  • Jong-Hyun Jeong,
  • Se-Hoon Shim,
  • Jung Goo Lee and
  • Kyung Joon Min
  • + 1 author

1 February 2023

Background. The Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) is an expert consensus guideline for depressive disorder created in 2002, and since then, four revisions (2006, 2012, 2017, 2021) have been published. In this study...

(This article belongs to the Section Mental Health)
  • Review
  • Open Access
17 Citations
4,520 Views
12 Pages

Ticagrelor Resistance in Cardiovascular Disease and Ischemic Stroke

  • Song He,
  • Yapeng Lin,
  • Quandan Tan,
  • Fengkai Mao,
  • Kejie Chen,
  • Junli Hao,
  • Weidong Le and
  • Jie Yang

1 February 2023

Ticagrelor, acting as a reversible platelet aggregation inhibitor of P2Y12 receptors (P2Y12R), is regarded as one of the first-line antiplatelet drugs for acute cardiovascular diseases. Though the probability of ticagrelor resistance is much lower th...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
8 Citations
3,158 Views
11 Pages

1 February 2023

Previously promising short-term H-Wave® device stimulation (HWDS) outcomes prompted this retrospective cohort study of the longer-term effects on legacy workers’ compensation chronic pain claimants. A detailed chart-review of 157 consecutiv...

(This article belongs to the Section Orthopedics)
  • Review
  • Open Access
44 Citations
6,287 Views
25 Pages

Association between Type 1 Diabetes Mellitus and Periodontal Diseases

  • Rosana Costa,
  • Blanca Ríos-Carrasco,
  • Luís Monteiro,
  • Paula López-Jarana,
  • Filipa Carneiro and
  • Marta Relvas

1 February 2023

Gingivitis and periodontitis are chronic inflammatory diseases that affect the supporting tissues of the teeth. Although induced by the presence of bacterial biofilms, other factor, such as tobacco smoking, drugs, and various systemic diseases, are k...

(This article belongs to the Special Issue Oral Health and Dental Care in Older Adults)

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J. Clin. Med. - ISSN 2077-0383