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Membranes, Volume 13, Issue 10

October 2023 - 43 articles

Cover Story: In this article, we have analyzed the structurally unresolved cytoplasmic loop of the human ABCG2 multidrug transporter. This membrane protein plays a crucial role in the absorption and excretion of xeno- and endobiotics, which contributes to cancer drug resistance and the development of gout. Although atomic structure data on ABCG2 have already been published, some flexible regions have not been addressed and can only be examined by generating mutations and studying the cellular expression and mode of trafficking to specific membrane regions using molecular dynamics. We found that a naturally occurring mutation (K360del) of ABCG2 increased cellular trafficking, while other mutations of several lysines or a potential phosphorylation site had no major effect either on the processing or the function of this transporter, despite increasing the loop mobility. View this paper
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Articles (43)

  • Communication
  • Open Access
2 Citations
2,541 Views
9 Pages

23 October 2023

For steric exclusion chromatography (SXC), hydrophilic stationary phases are used to capture the target molecule in the presence of polyethylene glycol. The influence of the structure and pore size of the stationary phase on the process requirements...

  • Feature Paper
  • Review
  • Open Access
14 Citations
6,894 Views
25 Pages

23 October 2023

Ethanol, a versatile chemical extensively employed in several fields, including fuel production, food and beverage, pharmaceutical and healthcare industries, and chemical manufacturing, continues to witness expanding applications. Consequently, there...

  • Article
  • Open Access
1 Citations
2,719 Views
11 Pages

Effect of the Degree of Li3PO4 Vapor Dissociation on the Ionic Conductivity of LiPON Thin Films

  • Alexander Kamenetskikh,
  • Nikolay Gavrilov,
  • Alexey Ershov and
  • Petr Tretnikov

23 October 2023

Thin films of solid-state lithium-ion electrolytes show promise for use in small-sized autonomous power sources for micro- and nanoelectronic elements. The high rate of vacuum-plasma synthesis (~0.5 μm/h) of lithium phosphor-oxynitride (LiPON) fil...

  • Article
  • Open Access
3 Citations
2,704 Views
17 Pages

22 October 2023

The features of organic fouling have been revealed for highly basic anion exchange membranes during prolonged electrodialysis in solutions containing the aromatic amino acid tyrosine. With increased operation time when using MA-41 heterogeneous membr...

  • Article
  • Open Access
9 Citations
2,960 Views
14 Pages

Study of the Physical, Chemical, and Structural Properties of Low- and High-Methoxyl Pectin-Based Film Matrices Including Sunflower Waxes

  • Mayra C. Chalapud,
  • Ma. de la Paz Salgado-Cruz,
  • Erica R. Baümler,
  • Amalia A. Carelli,
  • Eduardo Morales-Sánchez,
  • Georgina Calderón-Domínguez and
  • Alitzel B. García-Hernández

22 October 2023

The development of bio-based materials remains one of the most important alternatives to plastic materials. Although research in this field is growing, reporting various materials and methodologies, it is still necessary to increase exploration. The...

  • Article
  • Open Access
5 Citations
3,206 Views
22 Pages

Molecular Cloning, Expression and Transport Activity of SaNPF6.3/SaNRT1.1, a Novel Protein of the Low-Affinity Nitrate Transporter Family from the Euhalophyte Suaeda altissima (L.) Pall.

  • Olga I. Nedelyaeva,
  • Dmitrii E. Khramov,
  • Lyudmila A. Khalilova,
  • Alena O. Konoshenkova,
  • Anastasia V. Ryabova,
  • Larissa G. Popova,
  • Vadim S. Volkov and
  • Yurii V. Balnokin

22 October 2023

The SaNPF6.3 gene, a putative ortholog of the dual-affinity nitrate (NO3−) transporter gene AtNPF6.3/AtNRT1.1 from Arabidopsis thaliana, was cloned from the euhalophyte Suaeda altissima. The nitrate transporting activity of SaNPF6.3 was studied...

  • Article
  • Open Access
3 Citations
2,774 Views
30 Pages

22 October 2023

Although hollow fiber water gap membrane distillation (HF-WGMD) units offer certain advantages over other MD desalination systems, they still require enhancements in terms of distillate flux and productivity. Therefore, this work proposes a novel con...

  • Article
  • Open Access
4 Citations
2,568 Views
32 Pages

22 October 2023

Membrane distillation (MD) is an attractive process for the concentration of seawater brines. Modelling and simulation of membrane distillation processes requires a better knowledge of the heat transfer coefficients in spacer-filled channels which ar...

  • Review
  • Open Access
7 Citations
3,642 Views
14 Pages

Toxic Effects of Penetrating Cations

  • Svyatoslav Sokolov,
  • Anna Zyrina,
  • Sergey Akimov,
  • Dmitry Knorre and
  • Fedor Severin

22 October 2023

As mitochondria are negatively charged organelles, penetrating cations are used as parts of chimeric molecules to deliver specific compounds into mitochondria. In other words, they are used as electrophilic carriers for such chemical moieties as anti...

  • Review
  • Open Access
11 Citations
3,888 Views
24 Pages

21 October 2023

Since antiquity, humans have known about plants as a medicinal cure. Recently, plant extracts are attracting more attention as a result of their natural origin and wide range of desirable features. Nanotechnology’s progress and innovations enab...

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Membranes - ISSN 2077-0375